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Tolak Cream contains the active ingredient fluorouracil. It is a prescription medication applied to the skin to treat actinic keratosis.
Tolak Cream is used to treat actinic keratoses, which are rough, scaly patches of skin caused by long-term sun exposure.
These spots are considered precancerous because some may eventually develop into a type of skin cancer called squamous cell carcinoma.
Actinic keratoses commonly appear on sun-exposed areas such as the:
Tolak helps remove abnormal skin cells before they have a chance to progress further.
Fluorouracil belongs to a group of medications called antimetabolites.
It works by interfering with the way abnormal skin cells make and use DNA.
Actinic keratosis cells divide more rapidly than normal skin cells, so they are more sensitive to the effects of fluorouracil.
As Tolak begins to destroy abnormal cells, the treated skin may become:
These skin reactions are common during treatment and can be a sign that the medication is affecting the abnormal cells.
Your healthcare provider can tell you what level of skin reaction is expected and when you should contact them.
Tolak is intended for actinic keratosis and should not be used on other skin conditions unless your healthcare provider specifically recommends it.
It is not a general treatment for every type of rash, mole, or skin cancer.
After treatment, your healthcare provider may examine the treated skin to make sure the actinic keratoses have cleared and to check for any suspicious areas that need further evaluation.
Continue protecting your skin from the sun, since additional actinic keratoses can develop over time.
Tolak Cream is applied directly to areas of actinic keratosis on the face, ears, or scalp.
The usual schedule is:
Apply once daily for 4 weeks, or for the length of time your healthcare provider recommends.
Gently wash the area you are going to treat.
Rinse the skin and pat it completely dry before applying the medication.
Apply a thin layer of Tolak Cream over the affected area.
Use your fingertips to gently massage the cream evenly into the skin.
Use only enough cream to cover the area being treated.
Wash your hands thoroughly after applying Tolak, unless your hands are the area being treated.
Avoid transferring the cream to another person or to other areas of your body.
Tolak is for external skin use only.
Do not apply it:
If Tolak accidentally gets into your eyes, rinse them with plenty of water and seek medical advice.
Do not cover the treated skin with a tight or airtight bandage unless your healthcare provider specifically tells you to.
Covering the area can increase absorption of fluorouracil and may increase side effects.
Tolak can make treated skin more sensitive to sunlight.
Limit sun exposure during treatment and immediately afterward. Wear protective clothing and follow your healthcare provider’s advice about sun protection.
Treated skin may sunburn more easily.
The treated skin commonly becomes:
These reactions can become more noticeable as treatment continues and may remain for several weeks after treatment ends.
Contact your healthcare provider if the reaction becomes severe or difficult to tolerate.
If you miss an application, apply Tolak when you remember unless it is almost time for your next scheduled application.
If your next dose is approaching, skip the missed application and continue with your regular schedule.
Do not apply extra cream to make up for a missed dose.
Use Tolak once daily for the full 4-week treatment period as tolerated, unless your healthcare provider tells you to stop earlier.
Do not use more cream, apply it more frequently, or continue treatment longer than prescribed.
Tolak Cream (Fluorouracil) is available in the following forms and strength:
Tolak can harm a developing baby and should not be used during pregnancy.
Tell your healthcare provider if you are pregnant, think you may be pregnant, or plan to become pregnant before using Tolak.
Do not use Tolak if you have dihydropyrimidine dehydrogenase (DPD) deficiency.
People with this enzyme deficiency may not break down fluorouracil properly, which can lead to severe or potentially life-threatening toxicity.
Tolak is for use on the skin only.
Do not apply it:
If Tolak gets into your eyes, rinse them thoroughly with water and contact your healthcare provider if irritation continues.
Tolak can make treated skin much more sensitive to sunlight.
Avoid unnecessary sun exposure, tanning beds, and sun lamps during treatment and shortly afterward.
Wear protective clothing and follow your healthcare provider’s advice about sunscreen.
Redness, crusting, burning, and irritation are common during treatment, but severe reactions can sometimes occur.
Contact your healthcare provider if you develop:
A reaction that spreads beyond the treated area
Stop using Tolak and seek medical attention if you develop signs of a serious allergic reaction, such as hives, severe rash, swelling of the face or throat, or difficulty breathing.
Tolak contains peanut oil.
Tell your healthcare provider if you have a peanut allergy before using the cream.
Tolak should only be used on the areas of actinic keratosis your healthcare provider has told you to treat.
Do not use it on:
unless your healthcare provider specifically recommends it.
Do not cover treated skin with an airtight or occlusive dressing unless your healthcare provider tells you to.
Covering the area can increase fluorouracil absorption and may increase the risk of side effects.
Tell your healthcare provider if you are breastfeeding.
Your healthcare provider will decide whether Tolak is appropriate and which areas of the body should be avoided during treatment.
Keep Tolak out of the reach of children and pets.
Fluorouracil can be dangerous if swallowed or accidentally exposed to areas where it was not intended to be used.
Yes. Skin reactions are very common during treatment. You may develop redness, dryness, scaling, crusting, itching, burning, swelling, or skin erosion. These reactions may continue for several weeks after treatment ends.
The treated skin may remain irritated for several weeks after you finish the 4-week treatment course. Healing time varies depending on how strongly your skin reacts and how large an area was treated. Contact your healthcare provider if the reaction becomes severe or does not begin to improve.
No. Tolak Cream should not be used during pregnancy because fluorouracil can harm a developing baby. Women who can become pregnant should use effective birth control during treatment and for 1 month after the last application.
It is not known whether enough fluorouracil from Tolak Cream passes into breast milk to affect a nursing infant. Talk with your healthcare provider before breastfeeding while using Tolak. Together, you can decide whether to use Tolak or breastfeed.
Sun exposure should be limited during treatment and immediately afterward. Tolak can make treated skin more sensitive to ultraviolet light, which may increase irritation or sunburn. Wear protective clothing and follow your healthcare provider’s instructions about sun protection.
No. Do not apply Tolak on the eyelids, around the eyes, or directly in the eyes. Also avoid the nose, mouth, vagina, and other mucous membranes. If Tolak accidentally gets into your eyes, rinse them thoroughly with water and seek medical advice.
If you miss an application, apply Tolak when you remember unless it is almost time for your next scheduled dose. If your next application is approaching, skip the missed dose and continue with your normal schedule. Do not apply extra cream to make up for a missed dose.
Do not cover the treated area with an airtight or occlusive dressing unless your healthcare provider specifically tells you to. Covering the skin may increase absorption of fluorouracil and raise the risk of side effects.
Tolak is specifically approved for actinic keratoses on the face, ears, and scalp. Its safety and effectiveness have not been established for other areas of the body or for other skin conditions.
Yes. Tolak Cream contains peanut oil as an inactive ingredient. Tell your healthcare provider if you have a peanut allergy or have previously had a serious reaction to peanut products.
Store Tolak Cream at room temperature, generally between 20°C and 25°C (68°F to 77°F). Do not freeze it. Keep the tube tightly closed and out of the reach of children and pets. Fluorouracil can be dangerous if swallowed by pets.
| Generic name: | Fluorouracil |
|---|---|
| Formulation: | Cream |
| Strength(s): | 4% |
| Quantities Available: | 40g |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Tolak Cream (fluorouracil) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Tolak Cream is commonly prescribed to be applied once or twice daily to the affected area. For a 90-day supply, the quantity you will order would depend on the size of the tubes and the specific treatment plan recommended by your healthcare provider.
No, we do not sell fluorouracil directly, but you can still enjoy low prices on Tolak Cream, which contains fluorouracil as an active ingredient. You will need a valid prescription from your healthcare provider to purchase Tolak Cream. We require this to dispense the medication safely and appropriately. You can mail, fax, or upload your prescription through your online account.
Yes, we ship Tolak Cream (fluorouracil) to both the United States and Puerto Rico.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Tolak Cream (Fluorouracil). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Tolak Cream (Fluorouracil).
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