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Emend (active ingredient: aprepitant) is a prescription medication used to help prevent nausea and vomiting caused by certain medical treatments. It is used in adults and, for some conditions, in children 12 years of age and older.
Unlike medications that treat nausea after it starts, Emend is taken before treatment to help prevent nausea and vomiting from occurring.
Emend is approved for the following uses:
Emend is used to help prevent nausea and vomiting caused by cancer chemotherapy in adults and children 12 years of age and older.
Some chemotherapy medications can trigger nausea and vomiting immediately after treatment (acute nausea and vomiting) or several days later (delayed nausea and vomiting). Both can make it difficult to eat, drink, and continue cancer treatment.
Emend helps prevent:
It is commonly used as part of a combination of anti-nausea medications for people receiving highly emetogenic chemotherapy (HEC) or moderately emetogenic chemotherapy (MEC), which are chemotherapy treatments that have a high or moderate likelihood of causing nausea and vomiting.
Emend is also approved to help prevent postoperative nausea and vomiting (PONV) in adults.
Some people experience nausea or vomiting after surgery because of anesthesia or pain medications. Taking Emend before surgery can help reduce the risk of these symptoms, making recovery more comfortable.
Emend belongs to a group of medications called neurokinin-1 (NK1) receptor antagonists.
It works by blocking the action of substance P, a natural chemical in the brain that plays an important role in triggering the nausea and vomiting reflex.
By blocking substance P from attaching to NK1 receptors, Emend helps prevent the signals that cause nausea and vomiting before they occur.
Because Emend works through a different pathway than many other anti-nausea medications, it is often prescribed together with other antiemetics, such as corticosteroids and serotonin (5-HT₃) receptor antagonists, to provide better protection against nausea and vomiting caused by chemotherapy or surgery.
When taken as prescribed, Emend can help:
Emend capsules should be taken by mouth exactly as prescribed by your healthcare provider. The capsules may be taken with or without food and should be swallowed whole. Do not crush, chew, or open the capsules.
For the prevention of chemotherapy-induced nausea and vomiting (CINV), Emend is usually started 1 hour before your chemotherapy treatment. The medication is then continued for the next 2 days to help prevent delayed nausea and vomiting.
If you are receiving chemotherapy on Day 2 or Day 3, take your dose 1 hour before your chemotherapy session. If you are not receiving chemotherapy on those days, take your dose once daily in the morning, unless your healthcare provider instructs you otherwise.
Your healthcare provider will determine the appropriate dose based on:
Always follow your prescribed dosing schedule, and do not take more or less than the recommended dose.
Adults and Children 12 Years of Age and Older
For the prevention of chemotherapy-induced nausea and vomiting, the typical dosing schedule is:
Children 6 Months to 11 Years of Age
For children, the dose is based on body weight.
The typical dosing schedule is:
Your child’s healthcare provider will calculate the correct dose based on their weight and ensure it does not exceed the recommended maximum dose.
Emend (Aprepitant) is available in the following forms and strength:
Before taking Emend, tell your healthcare provider about your complete medical history and all medications you are taking. This helps ensure the medication is safe for you and reduces the risk of side effects and drug interactions.
Before starting Emend, let your healthcare provider know if you have or have ever had:
Because Emend is processed by the liver, your healthcare provider may monitor you more closely or adjust your treatment if you have liver problems.
Also provide a complete list of all the medications you take, including:
Emend can interact with many medications, which may affect how well they work or increase the risk of side effects.
Do not take Emend if you are allergic to aprepitant, fosaprepitant, or any of the other ingredients in the medication.
Like many medications, Emend contains inactive ingredients that may cause allergic reactions in some people.
Seek immediate medical attention if you develop symptoms of a serious allergic reaction, including:
If you have a history of medication allergies, tell your healthcare provider or pharmacist before starting treatment.
If you are pregnant, planning to become pregnant, or breastfeeding, tell your healthcare provider before taking Emend.
The effects of Emend during pregnancy are not fully known. It should only be used during pregnancy if your healthcare provider determines that the potential benefits outweigh the potential risks to the developing baby.
It is also not known whether Emend passes into breast milk. If you are breastfeeding or plan to breastfeed, discuss the risks and benefits of treatment with your healthcare provider before using this medication.
Emend may cause dizziness or tiredness in some people.
Until you know how the medication affects you:
It is also recommended to limit or avoid alcohol while taking Emend, as alcohol may increase dizziness, drowsiness, or other side effects.
For the prevention of chemotherapy-induced nausea and vomiting, Emend is usually taken 1 hour before chemotherapy. The typical adult dose is 125 mg on Day 1, followed by 80 mg once daily on Days 2 and 3, or as directed by your healthcare provider. Always take Emend exactly as prescribed. Do not change your dose or stop taking the medication without first consulting your healthcare provider.
Emend can interact with many medications, so it is important to tell your healthcare provider about all prescription medications, over-the-counter medicines, vitamins, and herbal supplements you are taking. In particular, avoid taking St. John’s wort, as it can reduce the effectiveness of Emend. Emend may also interact with certain medications, including blood thinners, some seizure medications, and other drugs that affect liver enzymes. Your healthcare provider will determine whether any dose adjustments or alternative medications are needed.
Do not use Emend if you are allergic to aprepitant or any of the other ingredients in the medication. You should also avoid taking Emend if your healthcare provider has advised against its use because of a serious medical condition or a potential drug interaction. Before starting treatment, tell your healthcare provider if you have liver disease, as Emend is processed by the liver. If you have severe liver impairment, your healthcare provider may monitor you more closely during treatment to help ensure the medication is safe and effective for you.
When taken as prescribed, Emend is generally considered safe and well tolerated. However, like all medications, it may cause side effects. Common side effects include headache, tiredness or fatigue, constipation, weakness, and nausea. Although serious side effects are uncommon, they can occur and may include liver problems, severe allergic reactions, and, in rare cases, seizures. Contact your healthcare provider immediately if you experience symptoms of a serious allergic reaction, severe abdominal pain, yellowing of the skin or eyes (jaundice), dark-colored urine, or any other unusual or severe symptoms while taking Emend.
Emend begins working within a few hours after you take your dose. Because it is taken before chemotherapy or surgery, it helps prevent nausea and vomiting before they begin. Its protective effects may last for several days, helping reduce both acute nausea and vomiting (within the first 24 hours) and delayed nausea and vomiting, which can occur up to 5 days after chemotherapy.
Yes, you can take other medications while taking Emend, but you should always tell your healthcare provider about all prescription medications, over-the-counter medicines, vitamins, and herbal supplements you are taking. Some medications can interact with Emend, making either medication less effective or increasing the risk of side effects. Before starting treatment, your healthcare provider or pharmacist can review your medications and check for any potential drug interactions to help ensure your treatment is safe and effective.
Yes. A generic version of Emend containing the active ingredient aprepitant is available. Generic aprepitant has the same active ingredient, strength, safety, and effectiveness as the brand-name medication and may be a more affordable treatment option.
| Generic name: | Aprepitant |
|---|---|
| Formulation: | Capsule |
| Strength(s): | 80mg, 125mg |
| Quantities Available: | 2, 6, 12 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Emend (aprepitant) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of symptoms without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Emend is available in dosages of 80 mg and 125 mg. The dosage and duration of treatment may vary based on factors such as the specific chemotherapy regimen and the healthcare provider’s instructions.
For example:
Yes, we sell aprepitant! You can enjoy low prices on your medication by ordering from our website. To place an order, you will need a valid prescription from your healthcare provider, which we require to dispense the medication safely and accurately. You can submit your prescription by mail, fax, or by uploading it through your online account.
Yes, we ship Emend (aprepitant) to both the United States and Puerto Rico.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Emend (Aprepitant). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Emend (Aprepitant).
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