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Actigall (active ingredient: ursodiol) is a prescription medication used to treat certain conditions involving the gallbladder and liver.
Actigall belongs to a group of medications called bile acid derivatives. It works by reducing the amount of cholesterol produced by the body and decreasing the absorption of cholesterol from the digestive tract. This helps lower the cholesterol content of bile, which can aid in dissolving certain types of gallstones and improving bile flow in liver conditions.
Actigall is used to help dissolve certain types of cholesterol gallstones in people who are not candidates for gallbladder removal surgery or who prefer a non-surgical treatment option.
It is most effective for:
Gallstones form when substances in bile, particularly cholesterol, become concentrated and harden into stones. By reducing the cholesterol content of bile, Actigall can gradually help dissolve these stones over time.
How Actigall Helps with Gallstones
Because gallstone dissolution occurs gradually, treatment may need to continue for several months or longer before significant results are seen.
Actigall is also used to treat primary biliary cholangitis (PBC), a chronic liver disease that affects the small bile ducts within the liver.
In PBC, the bile ducts become damaged over time, causing bile to build up in the liver. This can lead to inflammation, liver damage, and reduced liver function if left untreated.
Symptoms of Primary Biliary Cholangitis
Symptoms may include:
How Actigall Helps with PBC
Actigall contains ursodiol, a naturally occurring bile acid that changes the composition of bile.
For gallstones, ursodiol lowers the amount of cholesterol in bile, allowing cholesterol gallstones to gradually dissolve over time.
For primary biliary cholangitis, ursodiol helps improve bile flow through the liver and bile ducts. This reduces bile accumulation, decreases liver inflammation, and helps protect the liver from further damage.
When taken regularly as prescribed, Actigall can help manage symptoms, improve liver function, and support long-term treatment goals for both gallstone disease and primary biliary cholangitis.
Actigall is taken by mouth and should be used exactly as prescribed by your healthcare provider. Taking the medication consistently and following the recommended dosing schedule can help ensure the best possible results.
For the treatment of gallstones, ursodiol is usually taken two or three times daily with food or immediately after a meal. Taking the medication with food may help improve absorption and reduce stomach discomfort.
For the treatment of primary biliary cholangitis (PBC), ursodiol is typically taken two to four times daily with food, depending on the dose prescribed by your healthcare provider.
Swallow the tablets whole with a full glass of water. Do not crush, chew, or break the tablets unless your healthcare provider instructs you otherwise.
While taking ursodiol, your healthcare provider may recommend limiting foods that are high in cholesterol or calories, as these foods can contribute to gallstone formation. Certain medications, such as antacids, may also affect how well ursodiol works. Talk to your healthcare provider or pharmacist before taking antacids or other new medications while using Actigall.
If you have questions about how to take your medication, ask your healthcare provider or pharmacist for guidance.
Gallstone Dissolution
The recommended dosage for dissolving cholesterol gallstones is typically:
Your healthcare provider will calculate the appropriate dose based on your body weight and individual treatment needs.
Primary Biliary Cholangitis (PBC)
For the treatment of primary biliary cholangitis, the dosage is also generally based on body weight and is divided into multiple daily doses as directed by your healthcare provider.
Missed Dose
If you miss a dose of Actigall, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular dosing schedule.
Do not take two doses at the same time or take extra medication to make up for a missed dose, as this may increase the risk of side effects.
Taking Actigall consistently and following your healthcare provider’s instructions can help maximize its effectiveness and support long-term treatment success.
Actigall (Ursodiol) is available in the following forms and strength:
Before starting Actigall (ursodiol), tell your healthcare provider about your complete medical history, especially if you have liver disease, kidney disease, pancreatitis, or other digestive system disorders. These conditions may affect whether ursodiol is appropriate for you or may require closer monitoring during treatment.
People with liver or kidney problems may need a lower dose of ursodiol, while others may not be suitable candidates for treatment. Your healthcare provider will determine the safest and most effective treatment plan based on your individual health needs.
Actigall may interact with certain medications, which could affect how well the medication works or increase the risk of side effects. Be sure to tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, and herbal supplements you take.
Examples of medications that may interact with ursodiol include:
Your healthcare provider or pharmacist can help determine whether any medication adjustments are needed.
Actigall is not appropriate for all types of gallstones. People with calcified gallstones or certain other gallbladder conditions may not benefit from treatment. Your healthcare provider will determine whether ursodiol is suitable based on the type of gallstones you have.
Like all medications, ursodiol can cause side effects. Common side effects may include:
Contact your healthcare provider if these side effects become severe, persistent, or bothersome.
Although uncommon, ursodiol may affect liver or bile duct function. In rare cases, serious liver-related complications have been reported. Your healthcare provider may recommend periodic blood tests to monitor your liver function during treatment.
Seek medical attention if you develop symptoms that may indicate liver problems, such as:
If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider before taking Actigall. Your healthcare provider can help you understand the potential benefits and risks of treatment and determine whether the medication is appropriate for your situation.
Do not take Actigall if you have a known allergy or hypersensitivity to ursodiol or any of the ingredients in the medication. Seek immediate medical attention if you experience symptoms of an allergic reaction, including rash, itching, swelling, severe dizziness, or difficulty breathing.
Regular follow-up appointments and monitoring may be recommended to help ensure that Actigall remains safe and effective throughout your treatment.
Gallstone dissolution is a gradual process and requires patience. Depending on the size and type of your gallstones, it may take several months to up to two years for the stones to dissolve completely. Your healthcare provider may monitor your progress with imaging tests to determine how well the treatment is working. Continue taking Actigall exactly as prescribed, even if you do not notice immediate improvement.
Actigall may not be appropriate for everyone. You should not take ursodiol if you have a blocked bile duct, acute inflammation of the gallbladder, or a known allergy to ursodiol, bile acids, or any of the ingredients in the medication. People with liver disease or kidney disease may require closer monitoring or dose adjustments during treatment. Before starting Actigall, discuss your complete medical history with your healthcare provider so they can determine whether this medication is safe and appropriate for your specific condition.
Store Actigall at room temperature and keep it away from excessive heat, moisture, and direct light. Keep the medication in its original container and out of the reach of children and pets. Proper storage helps maintain the safety and effectiveness of the medication.
If you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed, talk to your healthcare provider before taking Actigall. Your healthcare provider can review the potential benefits and risks of treatment and determine whether ursodiol is an appropriate option for you during pregnancy or breastfeeding.
Yes. In addition to dissolving certain cholesterol gallstones, ursodiol may also be used to help prevent gallstones from forming in people who are at increased risk. For example, ursodiol may be prescribed for some individuals who are experiencing rapid weight loss, as rapid weight loss can increase the risk of gallstone formation. Your healthcare provider can determine whether preventive treatment is appropriate for your situation.
| Generic name: | Ursodiol |
|---|---|
| Formulation: | Capsule, Sustained Release Tablet, Tablet |
| Strength(s): | 250mg, 300mg, 500mg |
| Quantities Available: | 60, 90, 100, 120, 180, 400 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Actigall (ursodiol) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time. This is a common practice for prescription medications to ensure continuous treatment without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Actigall is commonly prescribed in dosages of 250 mg per capsule, taken once or twice daily depending on the condition being treated.
For a 90-day supply, if you’re taking it once daily, you would order 90 capsules (90 days x 1 capsule per day). If you’re taking it twice daily, you would order 180 capsules (90 days x 2 capsules per day).
Yes, we do sell ursodiol on our website. You can enjoy low prices and convenient ordering. However, please note that you will need a valid prescription from your healthcare provider to purchase ursodiol. We require this to dispense the medication safely and legally. You can easily provide your prescription by mailing, faxing, or uploading it through your online account during the ordering process.
Yes, we ship Actigall (ursodiol) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Actigall (Ursodiol). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Actigall (Ursodiol).
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