Indication
Zithromax DT (generically known as Azithromycin) is a prescription medication commonly used to treat a variety of bacterial infections such as respiratory tract infections, skin infections, and sexually transmitted infections. However, note that it may not be effective against viral infections such as the common cold or flu.
Zithromax DT belongs to the class of macrolide antibiotics. It works by inhibiting the growth of bacteria, thereby preventing the spread of infection. Azithromycin binds to the bacterial ribosome and inhibits the synthesis of proteins, which is essential for bacterial growth and replication. This can lead to the death of the bacteria and the resolution of the infection.
Use and Dosage
Azithromycin dispersible tablets are taken orally either with or without food. In the event of stomach upset, take the tablet with food. Typically, it is taken once per week on the same day each week. The tablets are designed to dissolve quickly in water for easy administration, particularly for children who have difficulty swallowing tablets. To use Zithromax DT dispersible tablets, you should first dissolve the tablet in a glass of water before drinking the mixture.
Antacids containing aluminum or magnesium may decrease the absorption of azithromycin if taken at the same time. If you take an antacid that contains aluminum or magnesium, wait at least 2 hours before or after taking azithromycin.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Side Effects
Common Side Effects of Zithromax DT (Azithromycin):
- Diarrhea
- Headache
- Nausea
- Stomach pain
- Vomiting
Serious Side Effects of Zithromax DT (Azithromycin):
- Blisters or peeling
- Dark-colored urine
- Dizziness
- Extreme tiredness
- Fainting
- Fast, pounding, or irregular heartbeat
- Fever and pus-filled, blister-like sores, redness, and swelling of the skin
- Flu-like symptoms
- Hives
- Hoarseness
- Itching
- Lack of energy
- Loss of appetite
- Pain in the upper right part of the stomach
- Pink and swollen eyes
- Rash with or without a fever
- Severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
- Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- Unusual bleeding or bruising
- Unusual muscle weakness or difficulty with muscle control
- Vomiting or irritability while feeding (in infants less than 6 weeks old)
- Wheezing or difficulty breathing or swallowing
- Yellowing of the skin or eyes
Forms and Strength
Zithromax DT (Azithromycin) is available in the following forms and strength:
Azithromycin: Dispersible Tablet
- 100 mg
Cautions
- Allergic reactions: Patients who are allergic to azithromycin or any of its ingredients should avoid taking the medication.
- Decreased liver function: Azithromycin can cause temporary liver dysfunction in some cases, and caution should be exercised when prescribing to patients with preexisting liver problems.
- Heart issues: In 2013, the FDA (Food and Drug Administration) issued a warning about the potential risk of fatal heart arrhythmias associated with azithromycin use, especially in patients with underlying risk factors such as QT interval prolongation, low potassium or magnesium levels, or bradycardia.
- Drug interactions: Azithromycin can interact with other medications, especially those that affect the heart rhythm or the liver, so caution should be exercised when taking other medications while on azithromycin.
- Potential for antibiotic resistance: Overuse and misuse of antibiotics like azithromycin can lead to the development of antibiotic-resistant bacteria, which makes treatment more difficult and can be dangerous.
- GI side effects: Azithromycin can cause gastrointestinal (GI) side effects such as abdominal pain, diarrhea, and nausea.
- Kidney problems: Azithromycin can cause temporary kidney problems in some cases, so caution is advised when prescribing to patients with preexisting kidney disease.
- Fetal harm during pregnancy: Azithromycin is considered a pregnancy category B drug, which means it is considered safe to use during pregnancy. However, caution is advised, and it should only be used during pregnancy if the benefits outweigh the risks.
- Breastfeeding: Azithromycin is excreted in breast milk and caution should be exercised when administering to nursing mothers.
- Myasthenia gravis: Azithromycin can exacerbate symptoms of myasthenia gravis, a neuromuscular disorder, so caution is advised when prescribing to patients with this condition.
Frequently Asked Questions (FAQ)
Can Zithromax DT be given to pets?
Yes, Zithromax DT can be given to pets such as cats and dogs for certain bacterial infections. However, it should only be administered under the guidance of a licensed veterinarian.
How long does it take for Zithromax DT to work?
The effectiveness of Zithromax DT depends on the type and severity of the infection being treated. Some infections may start to improve within a few days, while others may take several days or even weeks.
Is Azithromycin safe for infants?
Mass azithromycin treatment in infants aged 15 months did not result in significant adverse events.
Is azithromycin a strong antibiotic?
Azithromycin is used to prevent and treat a very serious type of infection (mycobacteria or MAC). It is a macrolide-type antibiotic. It works by stopping the growth of bacteria. This medication will not work for viral infections (such as common cold, flu).
Resources
- https://www.petplace.com/article/drug-library/drug-library/library/azithromycin-zithromax-for-cats-and-dogs
- https://www.webmd.com/drugs/2/drug-1527-2223/azithromycin-oral/azithromycin-600-mg-oral/details
- https://medlineplus.gov/druginfo/meds/a697037.html
- https://www.everydayhealth.com/drugs/azithromycin
- https://www.drugs.com/azithromycin.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/050710s44-050711s41-050784s28lbl.pdf
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