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Formulation: Tablet
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Formulation: Tablet
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Xeljanz (active ingredient: tofacitinib) is a prescription medication used to treat several chronic inflammatory and autoimmune conditions. It helps reduce inflammation by affecting specific pathways in the immune system that contribute to disease activity.
Xeljanz belongs to a class of medications known as Janus kinase (JAK) inhibitors. These medications work by blocking signals involved in the immune response, helping to reduce inflammation, pain, swelling, and tissue damage.
Xeljanz is indicated for adults with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response to, or cannot tolerate, methotrexate.
Rheumatoid arthritis is an autoimmune disease that causes inflammation of the joints, leading to symptoms such as:
By reducing inflammation, Xeljanz can help improve symptoms and physical function.
Xeljanz is also used to treat adults with active psoriatic arthritis (PsA) who have had an inadequate response to, or cannot tolerate, methotrexate or other disease-modifying antirheumatic drugs (DMARDs).
Psoriatic arthritis can cause:
Treatment with Xeljanz may help reduce disease activity and improve daily functioning.
Xeljanz is indicated for adults with moderately to severely active ulcerative colitis who have had an inadequate response to, lost response to, or cannot tolerate tumor necrosis factor (TNF) blocker therapy.
Ulcerative colitis is a chronic inflammatory bowel disease that can cause:
Xeljanz helps reduce inflammation in the digestive tract and may help control symptoms.
Xeljanz is also used to treat adults with active ankylosing spondylitis who have had an inadequate response to one or more TNF blockers.
Ankylosing spondylitis is an inflammatory condition that primarily affects the spine and can cause:
By lowering inflammation, Xeljanz may help improve mobility and reduce symptoms.
Xeljanz contains tofacitinib, a Janus kinase (JAK) inhibitor. JAK enzymes play an important role in transmitting signals that trigger inflammation and immune system activity.
By blocking these signals, Xeljanz helps:
Because Xeljanz affects the immune system, regular monitoring and follow-up appointments are important throughout treatment.
Xeljanz is available as immediate-release tablets and extended-release (ER) tablets. It should be taken exactly as prescribed by your healthcare provider and may be taken with or without food.
Swallow Xeljanz tablets whole. Do not crush, chew, or split the tablets unless instructed by your healthcare provider. Extended-release (ER) tablets should be swallowed whole and must not be crushed, split, or chewed, as this may affect how the medication is released into the body.
For best results, take Xeljanz at approximately the same time each day. Because dosage requirements vary depending on the condition being treated and the formulation prescribed, always follow your healthcare provider’s instructions and do not take more or less than prescribed.
Rheumatoid Arthritis and Psoriatic Arthritis
For adults with rheumatoid arthritis or psoriatic arthritis, the typical dose of immediate-release Xeljanz is:
An extended-release formulation is also available and may be prescribed as:
Ulcerative Colitis
For adults with ulcerative colitis, the dosage may vary depending on the stage of treatment.
A common dosing schedule includes:
Polyarticular Course Juvenile Idiopathic Arthritis
For eligible patients with polyarticular course juvenile idiopathic arthritis, the typical dose is:
Because Xeljanz affects the immune system, your healthcare provider may periodically monitor your blood counts, liver function, and other laboratory values to help ensure the medication remains safe and effective.
Xeljanz (Tofacitinib) is available in the following forms and strength:
Before taking Xeljanz (tofacitinib), tell your healthcare provider about your complete medical history, including any infections, heart conditions, immune system disorders, allergies, or history of cancer.
Xeljanz should not be used during pregnancy unless specifically recommended by your healthcare provider. It may harm an unborn baby.
It is not known whether tofacitinib passes into breast milk. Because of the potential risk to a nursing infant, breastfeeding is generally not recommended while taking Xeljanz. Talk to your healthcare provider if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.
Xeljanz affects the immune system and may increase the risk of serious infections, including infections that can become life-threatening.
Your risk may be higher if you:
Contact your healthcare provider immediately if you develop symptoms of an infection, such as:
Avoid close contact with people who have contagious illnesses, such as chickenpox, measles, or influenza.
Xeljanz carries a boxed warning for an increased risk of major cardiovascular events, including:
Tell your healthcare provider if you have heart disease or risk factors such as:
Your healthcare provider will determine whether Xeljanz is an appropriate treatment option for you.
Xeljanz may increase the risk of certain cancers in some patients.
Tell your healthcare provider if you:
Regular medical monitoring may be recommended during treatment.
Do not take Xeljanz if you are allergic to tofacitinib or any of the ingredients in the medication.
Seek immediate medical attention if you develop symptoms of a serious allergic reaction, including:
If you are unsure about the ingredients in Xeljanz, ask your pharmacist or review the Medication Guide.
Like all medications, Xeljanz may cause side effects. Your healthcare provider will prescribe the lowest effective dose needed to manage your condition while helping to reduce the risk of adverse effects.
Regular follow-up appointments and laboratory testing are important to monitor your response to treatment and identify any potential complications early.
Yes. Xeljanz works by suppressing certain immune system pathways that contribute to inflammation. While this can help control autoimmune conditions, it may also reduce your body’s ability to fight infections. Because of this, it is important to watch for signs of infection and contact your healthcare provider if you develop symptoms such as fever, chills, or a persistent cough.
Yes. Xeljanz is approved for the treatment of active psoriatic arthritis in adults who have had an inadequate response to, or cannot tolerate, certain other treatments, such as methotrexate or other disease-modifying antirheumatic drugs (DMARDs).
Yes. Xeljanz is approved as an adjunctive agent for the treatment of moderately to severely active ulcerative colitis in adults who have had an inadequate response to, lost response to, or cannot tolerate tumor necrosis factor (TNF) blocker therapy.
Xeljanz may be used with certain other medications prescribed for autoimmune and inflammatory conditions. However, combining medications can increase the risk of side effects, including serious infections. Before starting treatment, tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, and herbal supplements you take. Your healthcare provider can help determine whether combination therapy is appropriate for you.
The dosing schedule for Xeljanz depends on the condition being treated and the specific formulation prescribed. For many patients taking immediate-release Xeljanz tablets, the typical dose is 5 mg by mouth twice daily. Always take Xeljanz exactly as prescribed by your healthcare provider and follow their dosing instructions carefully to help ensure the medication is safe and effective.
| Generic name: | Tofacitinib |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 5mg, 10mg |
| Quantities Available: | 56, 60, 112, 120 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Xeljanz (tofacitinib) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Xeljanz is commonly prescribed in dosages of 5 mg or 10 mg, taken twice daily. For a 90-day supply, this means you would order 180 tablets (90 days x 2 tablets per day).
Yes, we do offer tofacitinib on our website! You can enjoy our low prices when purchasing this medication. However, please note that you’ll need a valid prescription from your healthcare provider in order for us to dispense the medication. You can conveniently provide your prescription by mailing, faxing, or uploading it through your online account.
Yes, we ship Xeljanz (tofacitinib) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Xeljanz (Tofacitinib). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Xeljanz (Tofacitinib).
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