Indications
Uribel is a prescription medication that is used to relieve discomfort, pain, frequent urge to urinate, and cramps/spasms of the urinary tract caused by a urinary tract infection or irritation. Uribel is a combination medication composed of five drugs, namely hyoscyamine, methenamine, methylene blue, phenyl salicylate, and sodium phosphate.
Hyoscyamine is an antispasmodic drug that relaxes the muscles of the urinary tract to relieve cramps/spasms, while methenamine and sodium phosphate work as urinary antiseptics that help to prevent the growth of bacteria in the urine. Methylene blue and phenyl salicylate work together to relieve inflammation and pain in the urinary tract.
Uses and Dosage
Uribel is available in capsule form and should be taken by mouth. The usual dosage for Uribel is one capsule taken 4 times a day for 7 to 10 days. The dosage may vary depending on your medical condition and response to treatment.
Take each dose with a full glass of water (8 ounces/240 milliliters) and avoid lying down for at least 10 minutes after taking the medication. Unless otherwise directed by a doctor, drink plenty of fluids while being treated with Uribel. If stomach upset occurs, Uribel can be taken with food.
Taking antacids along with Uribel may decrease the effectiveness of the medication, so it is recommended to take Uribel at least one hour before antacids. Additionally, consuming large amounts of caffeine-containing beverages like coffee or tea, eating large amounts of chocolate, or taking nonprescription products that contain caffeine may increase the side effects of Uribel.
If the condition does not improve after a few days or if signs of a urinary tract infection develop (such as painful urination), it is important to inform a healthcare professional.
Side Effect
Common Side Effects of Uribel (Methenamine/ Methylene Blue/ Sodium Phosphate Monobasic/ Phenyl Salicylate/ Hyoscyamine):
- Blue to blue-green urine or stool
- Blurred vision
- Cannot empty your bladder fully
- Difficult urination
- Dizziness
- Drowsiness
- Dry mouth
- Nausea
- Rapid heartbeat
- Redness of your skin (flushing)
- Vomiting
Serious Side Effects of Uribel (Methenamine/ Methylene Blue/ Sodium Phosphate Monobasic/ Phenyl Salicylate/ Hyoscyamine):
- Allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- Blurred vision
- Breathing problems
- Dizziness
- Rapid pulse
- Trouble passing urine or change in the amount of urine
Form and Strength
Uribel (Methenamine/ Methylene Blue/ Sodium Phosphate Monobasic/ Phenyl Salicylate/ Hyoscyamine) is available in the following forms and strength:
Uribel: Capsule
- 118/10/40.8/36/0.12mg
Caution
- Allergic reactions: Uribel may cause an allergic reaction in people who are sensitive to any of its ingredients. If you experience any symptoms of an allergic reaction, such as difficulty breathing, rash, or swelling, seek medical attention immediately.
- Drug interactions: inform your healthcare provider about all the other medications you are taking, including prescription drugs, over-the-counter medications, and dietary supplements. Some drugs may interact with Uribel, causing adverse reactions or making Uribel less effective.
- Pregnancy and breastfeeding: Uribel is not recommended for use during pregnancy or breastfeeding, as the safety of the medication has not been established in these populations.
- Medical conditions: People with certain medical conditions, such as glaucoma, myasthenia gravis, an enlarged prostate gland, or liver disease, may need to be cautious when taking Uribel, as the medication may worsen these conditions or interact with other medications used to treat them.
- Urine discoloration: Uribel may cause your urine to turn blue or green in color, which is normal and not harmful.
- Driving and operating machinery: Uribel may cause dizziness, drowsiness, or blurred vision. It is important to avoid activities that require alertness, such as driving or operating machinery, until you know how Uribel affects you.
- Renal and hepatic impairment: Uribel should be used with caution in patients with renal and hepatic impairment, as it may lead to worsening of their condition or increase the risk of adverse effects.
- Overdose: Taking more than the recommended dose of Uribel may lead to serious adverse events, such as confusion, agitation, hallucinations, and seizures. If you suspect an overdose, seek medical attention immediately.
- Storage: Uribel should be stored in a cool, dry place, away from moisture and heat, and out of the reach of children.
Frequently Asked Questions (FAQ)
Where should I store Uribel?
Uribel should be stored in a cool, dry place away from moisture and heat, and out of reach of children.
Will Uribel make my urine change color?
Uribel might turn your urine or stool blue or blue-green because of the methylene blue component of the medication. This is not harmful, and it should go away after you stop taking the medication.
Can Uribel be used during pregnancy or breastfeeding?
Uribel is not recommended for use during pregnancy or breastfeeding, as its safety in these populations has not been established.
Resources
- https://www.drugs.com/mtm/uribel.html
- https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fa2cc334-bd86-46cc-bc6a-12c71303f963
- https://www.mayoclinic.org/drugs-supplements/hyoscyamine-methenamine-methylene-blue-phenyl-salicylate-and-sodium-phosphate-oral-route/description/drg-20075036
- https://uribelinfo.com/
- https://www.goodrx.com/uribel/what-is
- https://www.webmd.com/drugs/2/drug-154228/uribel-oral/details
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