Prescription Required
Formulation: ER Capsule
Prescription Required
Formulation: ER Capsule
(Generic Alternative)
Select the prescribed dosage
Select the quantity to see the price.
* This price includes a dispensing fee, medical review fee, and packing fee.
Shipped and delivered directly to your doorstep
Apriso contains the active ingredient mesalamine. It is a prescription extended-release medication used to help maintain remission from ulcerative colitis in adults.
Maintenance treatment helps keep the condition under control after active symptoms have improved. Apriso is not specifically approved to treat an active ulcerative colitis flare.
Ulcerative colitis is a long-term inflammatory bowel disease that affects the inner lining of the large intestine, also called the colon, and the rectum.
The inflammation usually begins in the rectum and may spread into other parts of the colon. The affected lining may become swollen, irritated, and covered with small sores.
During an active flare, symptoms may include:
Symptoms may improve for a period and then return later.
Remission means that the symptoms and inflammation of ulcerative colitis have significantly improved or are no longer active.
Apriso is used to help maintain this period of remission. It may reduce the chance that symptoms and inflammation will return.
Continue taking Apriso every day as prescribed, even when you feel well. Ulcerative colitis can become active again without causing obvious symptoms at first.
Apriso is approved for maintaining remission in adults. It is not specifically approved to bring an active flare under control.
During a flare, a healthcare provider may recommend a different mesalamine formulation, corticosteroid, biologic medication, or another treatment depending on the severity and location of the inflammation.
Do not increase your Apriso dose or use leftover medications to treat worsening symptoms without medical guidance.
Apriso belongs to a group of medications called aminosalicylates.
The exact way mesalamine works is not completely understood. It is believed to reduce the production and activity of substances that cause inflammation inside the colon.
This may help:
Apriso acts mainly within the colon rather than throughout the entire body.
Apriso is supplied as an extended-release capsule.
The capsule contains granules designed to release mesalamine gradually as the medication moves through the digestive system. This allows the medicine to reach the colon, where ulcerative colitis causes inflammation.
The capsules must be swallowed whole. Cutting, crushing, chewing, or breaking them may interfere with the extended-release design.
When Apriso is working effectively, it may help you remain free from symptoms such as:
You may not feel a noticeable effect while taking maintenance treatment. Feeling well can be a sign that the medication is successfully keeping the condition under control.
Ulcerative colitis is a long-term condition, so Apriso may be prescribed for an extended period.
Continue taking it until your healthcare provider recommends a change. Stopping maintenance treatment without medical advice may increase the chance of another flare.
The length of treatment depends on your symptoms, history of flare-ups, response to therapy, and risk of side effects.
Mesalamine can sometimes affect kidney function. Your healthcare provider should assess your kidneys before treatment and periodically while you are taking Apriso.
Monitoring may include:
Regular follow-up is important even when your ulcerative colitis appears well controlled.
Contact your healthcare provider if you develop:
These symptoms may mean the condition is becoming active again or that another medical problem is present.
Rarely, mesalamine may cause an acute intolerance reaction that can resemble an ulcerative colitis flare.
Possible symptoms include worsening abdominal pain, bloody diarrhea, fever, headache, or rash. Contact your healthcare provider promptly if your symptoms suddenly become worse after starting Apriso.
Apriso may be one part of a broader ulcerative colitis treatment plan.
Other parts may include:
Apriso helps maintain control of ulcerative colitis, but it does not permanently cure the condition.
Use it consistently and contact your healthcare provider if symptoms return, become worse, or change from your usual pattern.
Take Apriso exactly as prescribed by your healthcare provider.
Apriso is an extended-release form of mesalamine used to maintain remission from ulcerative colitis in adults. It is taken by mouth once daily in the morning.
The usual adult dose is 1.5 grams once daily.
This equals four 0.375-gram capsules taken together in the morning as one complete dose. Do not divide the four capsules into several doses unless your healthcare provider gives you different instructions.
Apriso may be taken with or without food.
Try to take the capsules at approximately the same time every morning. Following a regular schedule can make it easier to remember your dose.
You may choose to take Apriso with breakfast or on an empty stomach, but follow any specific instructions given by your healthcare provider.
Swallow each capsule whole with water.
Do not:
Apriso uses a delayed- and extended-release design to deliver mesalamine gradually into the digestive tract. Damaging the capsule may interfere with how and where the medication is released.
Tell your healthcare provider or pharmacist if you have difficulty swallowing the capsules whole.
Do not open the capsule or mix its contents with food unless your healthcare provider confirms that this is safe for your exact product. Different mesalamine brands have different administration instructions and should not be used in the same way.
Drink an adequate amount of water and other fluids during treatment unless your healthcare provider has advised you to limit fluids.
Mesalamine may contribute to kidney stones in some people. Staying properly hydrated may help reduce this risk.
Contact your healthcare provider if you develop severe pain in your side or lower back, blood in the urine, nausea, vomiting, or difficulty urinating.
Avoid taking Apriso at the same time as antacids unless your healthcare provider or pharmacist says the combination is appropriate.
Antacids may change the acidity of the digestive tract and interfere with the way Apriso releases mesalamine.
Ask your pharmacist how much time to leave between Apriso and an antacid if both treatments are needed.
Apriso is approved for maintaining remission from ulcerative colitis in adults.
Its safety and effectiveness have not been established for children under the current prescribing information. A healthcare provider may choose another mesalamine product with dosing instructions designed for children.
Do not give Apriso to a child unless it has been specifically prescribed for that child.
Apriso is used after ulcerative colitis symptoms have improved and the condition is in remission.
It helps keep inflammation under control and may reduce the risk of symptoms returning. It is not specifically approved to treat an active ulcerative colitis flare.
Continue taking Apriso every day even if you feel well. Feeling well does not always mean that inflammation cannot return.
Mesalamine is available in several tablets, capsules, suppositories, and enemas.
These products are not always interchangeable. They may release the medication in different areas of the digestive tract and may have different:
Do not substitute another mesalamine product for Apriso without approval from your healthcare provider or pharmacist.
Take a missed dose as soon as you remember unless it is almost time for your next scheduled morning dose.
If the next dose is due soon, skip the missed dose and return to your regular schedule.
Do not take two doses together or take extra capsules to make up for a missed dose.
Do not automatically take another dose if you vomit after taking Apriso.
Contact your healthcare provider or pharmacist for advice, especially if you can see intact capsules in the vomit. Taking another full dose without guidance could result in too much medication.
Ulcerative colitis is a long-term condition, so maintenance treatment may continue for months or longer.
Do not stop taking Apriso because your symptoms have disappeared. Stopping treatment without medical guidance may increase the chance of another flare.
Your healthcare provider will decide how long you should continue based on your history, symptoms, test results, and response to treatment.
Mesalamine may affect kidney function in some people.
Your healthcare provider should evaluate your kidney function before treatment begins and periodically while you are taking Apriso.
Monitoring may involve blood or urine tests. Tell your healthcare provider if you have kidney disease or take other medications that may affect the kidneys.
Attend all scheduled follow-up appointments, even when you have no symptoms.
Your healthcare provider may monitor:
Additional testing may include blood tests, stool tests, or a colonoscopy.
Contact your healthcare provider if you develop:
Do not increase the Apriso dose on your own. Another medication may be needed to treat an active flare.
Take four 0.375-gram capsules together once daily in the morning. Swallow each capsule whole, avoid taking it with antacids, and drink enough fluids.
Continue taking Apriso even when you feel well. Do not change the dose, switch mesalamine products, or stop treatment without speaking with your healthcare provider.
Apriso (Mesalamine) is available in the following forms and strength:
Apriso may affect kidney function. Rare but serious kidney problems may include kidney inflammation, reduced kidney function, or kidney failure.
The risk may be higher if you already have kidney disease or take other medications that can affect the kidneys.
Your healthcare provider should check your kidney function before treatment begins and periodically while you are taking Apriso.
Contact your healthcare provider if you develop:
Some people may develop a sudden intolerance reaction to mesalamine. The symptoms can resemble an ulcerative colitis flare.
Possible symptoms include:
Stop taking Apriso and contact your healthcare provider promptly if these symptoms develop. Medical assessment is needed to determine whether they are caused by the medication or active ulcerative colitis.
Tell your healthcare provider if you have liver disease or abnormal liver test results before taking Apriso.
People with liver problems may require closer monitoring because mesalamine can rarely worsen liver function.
Contact your healthcare provider if you develop yellowing of the skin or eyes, dark urine, severe nausea, unusual tiredness, or pain in the upper-right side of the abdomen.
Older adults may be more sensitive to some of the effects of Apriso, especially if they have reduced kidney function or other medical conditions.
Rare blood disorders have been reported with mesalamine. Your healthcare provider may order blood tests to monitor your blood cell counts during treatment.
Contact your healthcare provider if you develop:
Attend all scheduled appointments and laboratory tests while taking Apriso.
Your healthcare provider may monitor your kidney function, liver function, blood-cell counts, ulcerative colitis symptoms, and response to treatment. Do not stop Apriso or change your dose without medical guidance unless you develop symptoms of a serious reaction.
Apriso is taken by mouth as an extended-release capsule. The usual adult dose is taken once daily in the morning, with or without food. Swallow the capsules whole with water. Do not crush, chew, split, or open them. Take Apriso at approximately the same time each day and follow the exact instructions on your prescription label.
Tell your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Mesalamine may be used during pregnancy or breastfeeding when a healthcare provider decides that the benefits are greater than the possible risks. Small amounts may pass into breast milk. A breastfed baby should be monitored for diarrhea or other unusual symptoms. Do not start or stop Apriso without medical guidance.
Take the missed dose as soon as you remember. However, skip it if it is almost time for your next scheduled dose. Continue with your regular morning schedule. Do not take two doses at once or take extra capsules to make up for a missed dose.
Apriso may interact with certain medications. Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, supplements, and herbal products you use. Extra caution may be needed with medications that affect the kidneys. Antacids may also interfere with how Apriso releases mesalamine. Do not start, stop, or change another medication without speaking with your healthcare provider.
Apriso is used to maintain remission from ulcerative colitis. This means it helps prevent symptoms from returning after the condition is already under control. You may not notice an immediate effect because the goal is to keep you feeling well and reduce the risk of another flare. Continue taking Apriso every day as prescribed. Contact your healthcare provider if diarrhoea, bleeding, abdominal pain, or bowel urgency returns.
| Generic name: | Mesalamine |
|---|---|
| Formulation: | ER Capsule |
| Strength(s): | 0.375g |
| Quantities Available: | 120 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Apriso (mesalamine) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time. This quantity is often sufficient for managing chronic conditions like ulcerative colitis, which require ongoing maintenance therapy.
Here’s what you need to know:
Dosage and Quantity: Apriso is usually prescribed as 1.5 grams daily, which is equivalent to 4 capsules taken once daily. For a 90-day supply, you would order 360 capsules (4 capsules per day x 90 days).
Yes, we sell mesalamine at our pharmacy, and you can enjoy competitive prices. However, to purchase mesalamine, you will need a valid prescription from your healthcare provider. We require this to dispense the medication safely and appropriately. You can provide your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Apriso (mesalamine) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Apriso (Mesalamine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Apriso (Mesalamine).
REVIEWS