Timoptic XE Ophthalmic Gel (Timolol Maleate)

Prescription Prescription Required     Customer Reviews
Timoptic XE Ophthalmic Gel Brand
Dosage Quantity & Price
Timolol Maleate (Generic alternate to Timoptic XE Ophthalmic Gel) Generic
Dosage Quantity & Price
  • We are Certified
  • Cipa Certified Canadian
  • Norton Shopping Guarantee
  • 5 Star Excellence award from Shopper Approved for collecting at least 100 5 star reviews

Table of contents:

Timoptic-XE is an ophthalmic medication that treats high pressure inside the eye due to glaucoma (open angle-type) or other eye diseases (such as ocular hypertension). It contains the active ingredient timolol maleate and is available in sterile ophthalmic gel forming solution with concentrations of 0.25% and 0.5%.

Timoptic-XE works as a non-selective beta-adrenergic receptor blocking agent, which decreases the amount of fluid in the eye, thus reducing pressure. It works by decreasing the amount of fluid within the eye.

Use and Dosage

Use Timoptic XE Ophthalmic Gel in the affected eye(s) once per day. To ensure efficacy, apply other eye medications at least 10 minutes before the timolol gel solution.

Before applying eye drops, wash your hands thoroughly. To avoid any chance of the dropper tip becoming contaminated, do not let it touch your eye or any other surface. Remove contact lenses prior to using the eye drops. Your doctor can inform you how long to wait after using the gel before placing your contact lenses. With the cap securely fastened, turn the eye drop bottle over and shake it briefly before every use. It is not necessary to shake the container more than one time.

Tilt your head back, look upward, and pull down your lower eyelid to create a pouch. Hold the dropper directly over your eye and put one drop into your eye. Look downward and gently close your eyes for one to two minutes. Place one finger on the corner of your eye near your nose and apply gentle pressure. Do not blink or rub your eye as this will prevent the medication from draining out. Repeat these steps in your other eye if instructed to do so.

Do not rinse the dropper. After each use, replace the dropper cap. To receive the maximum benefit of Timoptic XE Ophthalmic Gel, use it frequently, at the same time every day, as advised by your doctor. Continue using this medication even if you feel better. Most people with glaucoma or high pressure in the eyes do not experience any symptoms.

Side Effects

Common Side Effects of Timoptic XE Ophthalmic Gel (Timolol Maleate):

  • Blurred vision
  • Cough
  • Diarrhea
  • Dizziness
  • Double vision
  • Drooping eyelid
  • Drowsiness
  • Dry mouth
  • Dry or watery eyes
  • Eye discomfort or pain
  • Feeling as if something is in the eye
  • Headache
  • Loss of appetite
  • Nausea
  • Numbness/tingling/cold feeling in your hands or feet
  • Psoriasis
  • Ringing in your ears
  • Seeing halos around lights
  • Sensitivity to light
  • Skin rash or worsening
  • Sleep problems (insomnia)
  • Stomach upset
  • Stuffy nose
  • Temporary blurred vision
  • Temporary burning/stinging/itching/redness of the eye
  • Upset stomach
  • Weakness

Serious Side Effects of Timoptic XE Ophthalmic Gel (Timolol Maleate):

  • Blurred vision
  • Chest pain
  • Confusion
  • Crusting or drainage of the eye
  • Depression
  • Difficulty breathing
  • Eye pain
  • Eye swelling
  • Hallucinations
  • Hives
  • Lightheadedness
  • Muscle weakness
  • Numbness or cold feeling in your hands and feet
  • Redness or severe discomfort of the eyes
  • Seeing halos around the lights
  • Severe stinging or burning after using the medication
  • Slow heartbeats
  • Swelling of your face lips tongue or throat
  • Tunnel vision
  • Unusual thoughts or behavior
  • Wheezing

Forms and Strength

Timoptic XE Ophthalmic Gel (Timolol Maleate) is available in the following forms and strength:

Timoptic XE Ophthalmic Gel: Ophthalmic Gel

  • 0.25%
  • 0.5%

Timolol Maleate: Ophthalmic Gel

  • 0.25%


  • People with certain medical conditions such as asthma, chronic obstructive pulmonary disease (COPD), diabetes, or heart diseases should use this medication with caution and under the supervision of a healthcare provider.
  • Timoptic XE Ophthalmic Gel may cause blurred vision, so people should use caution while driving or operating machinery until they know how this medication affects them.
  • Timoptic XE Ophthalmic Gel can interact with other medications that are used to treat high blood pressure or heart conditions. Inform a healthcare provider of all medications being taken to avoid drug interactions.
  • People with a history of severe allergic reactions to Timoptic XE Ophthalmic Gel or other beta-blockers should not use it.
  • Timoptic XE Ophthalmic Gel should not be used by women who are pregnant or breastfeeding without consulting a healthcare provider first.
  • The long-term safety of Timoptic XE Ophthalmic Gel in children has not been established, so it should only be used in children under the supervision of a healthcare provider.
  • People who wear contact lenses should remove them before using it, as the preservatives in the medication can be absorbed by the lenses and cause eye irritation.
  • Timoptic XE may cause a decrease in blood pressure or worsen existing heart failure. People with heart problems should use it with caution and under the supervision of a healthcare provider.
  • Timoptic XE may cause an increase in low-density lipoprotein (LDL) cholesterol levels in some people. Healthcare providers should monitor cholesterol levels in individuals using this medication.
  • Timoptic XE may mask symptoms of hypoglycemia in people with diabetes. Healthcare providers should monitor blood sugar levels carefully in individuals using the gel.
  • Timoptic XE may worsen symptoms in people with asthma or COPD. People with respiratory problems should use it with caution and under the supervision of a healthcare provider.
  • People with a history of eye surgery or eye trauma should use it with caution and under the supervision of a healthcare provider.
  • Timoptic XE may cause a rebound effect in some people when it is discontinued. Healthcare providers should gradually taper the medication before discontinuing it to avoid this effect.
  • Timoptic XE may cause skin reactions in some people. If a rash or itching occurs, discontinue use, and contact a healthcare provider.
  • Timolol maleate is a non-selective beta-adrenergic receptor blocking agent, which means it can affect other parts of the body in addition to the eyes. Therefore, it may be contraindicated in people with certain medical conditions, such as asthma, heart failure, heart block, and bradycardia.

Frequently Asked Questions (FAQ)

Does Timoptic XE Ophthalmic Gel lower eye pressure?

Yes, Timoptic XE Ophthalmic Gel (Timolol Maleate) is used to lower intraocular pressure (IOP) in people with ocular hypertension and chronic open-angle glaucoma.

How long does it take for Timoptic XE Ophthalmic Gel to work?

Timoptic XE Ophthalmic Gel begins working within 20-30 minutes after it is applied to the eye, and the maximum effect is usually achieved within 1-2 hours.

Is Timoptic XE Ophthalmic Gel safe during pregnancy or breastfeeding?

The safety of Timoptic XE Ophthalmic Gel during pregnancy and breastfeeding has not been established. Speak with your healthcare provider if you are pregnant or breastfeeding before using the gel.

How often should I use Timoptic XE Ophthalmic Gel?

One drop in the affected eye(s) once daily.


It's important to purchase Timoptic XE Ophthalmic Gel from verified Canadian pharmacy.

Additional information

Generic name:

Timolol Maleate, Timolol maleate


Ophthalmic Gel


0.25%, 0.50%

Quantities Available:

5mL, 7.5mL, 10mL, 15mL