Thorazine (Chlorpromazine)

Indications

Thorazine, also known as Chlorpromazine, is an antipsychotic medication used to treat psychotic disorders such as schizophrenia or manic depression, and certain mental/mood disorders. It works by blocking certain chemicals in the brain to help reduce symptoms such as hallucinations, delusions, and agitation.

Chlorpromazine is a powerful antipsychotic medication used to treat severe mental illnesses such as schizophrenia and bipolar disorder. It can be used to treat nausea and vomiting, anxiety before surgery, and other conditions.

Uses and Dosage

Chlorpromazine is available in tablet form and is taken orally with or without food as prescribed by the healthcare provider, usually 2-4 times a day. The dosage is determined based on the individual's medical condition, age, and response to treatment, and in children, it is also based on weight. To minimize the possibility of side effects, the healthcare provider may start the patient on a low dose and gradually increase it. Follow the healthcare provider's instructions meticulously.

The dose varies depending on the condition you are taking chlorpromazine for. In general, the typical dose ranges from 10 mg to 50 mg by mouth two to four times a day. If you are taking chlorpromazine for restlessness and anxiety before surgery, the typical dose is 25 mg to 50 mg by mouth once, 2 to 3 hours before your procedure.

Side effect

Common Side Effects of Thorazine (Chlorpromazine):

• Anxiety
• Blurred vision
• Breast swelling or discharge
• Changes in menstrual periods
• Constipation
• Dizziness
• Drowsiness
• Dry mouth
• Impotence
• Sleep problems (insomnia)
• Stuffy nose
• Swelling in hands or feet
• Trouble having an orgasm
• Weight gain

Serious Side Effects of Thorazine (Chlorpromazine):

• Big appetite
• Breast growth and milk production
• Fever
• Sexual dysfunction
• Skin and eye color changes
• Weight gain
• Yellowing of the skin and eyes (jaundice)

Form and Strength

Thorazine (Chlorpromazine) is available in the following forms and strength:

Chlorpromazine: Tablet

• 25 mg
• 50 mg
• 100 mg

Caution

• Chlorpromazine can cause serious side effects, including tardive dyskinesia, a movement disorder that can cause uncontrollable facial movements.
• Elderly patients with dementia-related psychosis who are treated with chlorpromazine are at an increased risk of death.
• Chlorpromazine can cause serious side effects, including tardive dyskinesia, a movement disorder that can cause uncontrollable facial movements.
• Caution is advised in patients with hepatic impairment.
• Chlorpromazine may interact with other medications, keep a list of all products being used and inform the healthcare provider.
• Chlorpromazine can cause a rare but life-threatening condition called neuroleptic malignant syndrome (NMS). Symptoms include high fever, fast heart rate, full body stiffness, and confusion.
• Chlorpromazine may cause drowsiness, blurred vision, and dizziness. Avoid driving, operating machinery, or undertaking any activities that require alertness or clear vision until it is safe to do so.
• Alcohol and marijuana (cannabis) can increase the risk of dizziness or drowsiness, and the consumption of alcoholic beverages should be avoided while taking chlorpromazine. It is important to inform the healthcare provider if marijuana (cannabis) is being used.
• Before taking chlorpromazine, tell your doctor or pharmacist if you are allergic to it; or to other phenothiazine drugs (such as perphenazine, thioridazine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Frequently Asked Questions (FAQ)

Can Thorazine cause addiction or dependence?

Thorazine does not typically cause addiction or dependence if taken as prescribed, but it may cause withdrawal symptoms if abruptly stopped.

How long does it take for Thorazine to start working?

It can take several days or weeks for Thorazine to reach its full effect, but some improvement may be noticed within the first few days of starting treatment.

Can I drink alcohol while taking Thorazine?

Patients taking Thorazine should avoid alcohol as it may increase the risk of side effects such as drowsiness or dizziness.

Is Thorazine safe for use during pregnancy or breastfeeding?

Patients should consult with their physician before taking Thorazine during pregnancy or breastfeeding, as it may pose risks to the developing fetus or nursing infant.

Can Thorazine be used to treat anxiety or depression?

While Thorazine is primarily used to treat psychotic disorders, it may also be used to treat anxiety or depression in some cases.

Resources

• https://www.webmd.com/drugs/2/drug-9543/thorazine-oral/details
• https://www.goodrx.com/chlorpromazine/what-is#side-effects
• https://www.verywellmind.com/thorazine-chlorpromazine-side-effects-379006
• https://www.rxlist.com/thorazine-side-effects-drug-center.htm
• https://my.clevelandclinic.org/health/drugs/18811-chlorpromazine-tablets