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Compazine

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Prescription Prescription Required FormationFormulation: Tablet

Prochlorperazine

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Comprazine (active ingredient: prochlorperazine) is a prescription medication used to treat nausea and vomiting, vertigo, and certain psychiatric conditions. It belongs to a class of medications known as phenothiazines.

Comprazine works by affecting specific chemical messengers in the brain, helping to control symptoms such as nausea, dizziness, and certain mental health symptoms.

What Is Comprazine Used For?

Nausea and Vomiting

Comprazine is commonly prescribed to prevent or treat severe nausea and vomiting caused by a variety of conditions, including:

  • Chemotherapy treatments
  • Surgery
  • Migraine headaches
  • Other medical conditions associated with nausea and vomiting

By helping control these symptoms, Comprazine can improve comfort and reduce the risk of dehydration and other complications.

Vertigo

Comprazine is also used to manage vertigo, a sensation that you or your surroundings are spinning or moving.

Vertigo may be caused by conditions affecting the vestibular system, which helps control balance and spatial orientation. Symptoms may include:

  • Dizziness
  • Spinning sensations
  • Loss of balance
  • Nausea associated with dizziness

Comprazine can help reduce these symptoms and improve overall comfort.

Psychiatric Disorders

In some cases, Comprazine may be prescribed to help manage certain psychiatric conditions, including:

  • Schizophrenia
  • Generalized anxiety disorder (GAD)

When used for psychiatric conditions, Comprazine may help reduce symptoms such as agitation, anxiety, and disturbances in thinking or perception.

How Does Comprazine Work?

Comprazine belongs to a group of medications called phenothiazines.

It works primarily by blocking dopamine receptors in the brain. Dopamine is a neurotransmitter involved in several functions, including mood, movement, and the body’s vomiting response.

By blocking dopamine receptors, Comprazine helps:

  • Reduce nausea and vomiting
  • Control symptoms of vertigo
  • Manage certain psychiatric symptoms

Comprazine also affects serotonin activity, which contributes to its anti-nausea and anti-vomiting effects.

Benefits of Comprazine

When used as prescribed, Comprazine may help:

  • Prevent or treat nausea and vomiting
  • Reduce dizziness and vertigo symptoms
  • Improve balance-related discomfort
  • Manage symptoms of certain psychiatric disorders
  • Improve overall comfort and quality of life

Important Reminder

Comprazine should be used exactly as prescribed by your healthcare provider. Because it affects brain chemicals, it may cause side effects such as drowsiness, dizziness, or movement-related symptoms in some individuals. Regular follow-up with your healthcare provider can help ensure the medication is working safely and effectively.

Compazine is available as an oral tablet and is commonly prescribed in 5 mg tablets. Depending on the condition being treated, it is usually taken three or four times daily, with or without food.

Take Compazine exactly as prescribed by your healthcare provider. Do not take more or less than the recommended dose, and do not continue taking it longer than instructed. If the medication causes stomach upset, taking it with food may help.

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a missed dose.

Recommended Dosage

The appropriate dosage of Compazine depends on the condition being treated, the severity of symptoms, and your individual response to the medication.

Severe Nausea and Vomiting

For the treatment of severe nausea and vomiting, the usual dosage is:

  • 5 mg to 10 mg by mouth every 6 to 8 hours
  • Maximum daily dose: 40 mg

Non-Psychotic Anxiety

For the short-term treatment of non-psychotic anxiety, the typical dosage is:

  • 5 mg to 10 mg by mouth three times daily

Psychosis

For psychotic disorders, the usual dosage is:

  • 10 mg to 25 mg by mouth three times daily

Your healthcare provider may adjust the dose based on your symptoms and treatment response.

Schizophrenia

For schizophrenia, the typical dosage is:

  • 10 mg to 25 mg by mouth three times daily

The dose may be adjusted over time to achieve the best balance between symptom control and side effects.

Important Dosing Tips

  • Take Compazine exactly as prescribed.
  • Take doses at evenly spaced intervals throughout the day.
  • Do not exceed the prescribed daily dose.
  • Do not stop the medication without consulting your healthcare provider.
  • If you miss a dose, do not double up on your next dose.

Regular follow-up appointments can help ensure that Compazine is working effectively and safely for your condition.

Common Side Effects of Compazine (Prochlorperazine):

  • Agitation, feeling jittery, trouble sleeping
  • Constipation
  • Dizziness
  • Drowsiness
  • Dry mouth, stuffy nose
  • Headache
  • Increased appetite
  • Itching, rash, redness, or discoloration of the skin
  • Nausea
  • Weight gain

Serious Side Effects of Compazine (Prochlorperazine):

  • Blurred vision
  • Increased sensitivity of the skin to sunlight
  • Irregular menstrual periods
  • Jitteriness
  • Trouble sleeping
  • Impotence, abnormal ejaculation.

Compazine (Prochlorperazine) is available in the following forms and strengths:

Compazine: Tablet

  • 5 mg

Prochlorperazine: Tablet

  • 5 mg
  • 10 mg

Before taking Compazine, inform your healthcare provider about your medical history, allergies, and all medications you are taking. Certain conditions may increase your risk of serious side effects.

Allergic Reactions

Do not take Compazine if you are allergic to prochlorperazine or other related phenothiazine medications, including:

  • Chlorpromazine
  • Fluphenazine
  • Perphenazine
  • Promethazine
  • Thioridazine
  • Trifluoperazine

Seek immediate medical attention if you develop signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing.

Dizziness and Fainting

Compazine may cause:

  • Dizziness
  • Lightheadedness
  • Fainting, especially when standing up quickly

To help reduce these effects, rise slowly when getting up from a sitting or lying position. If dizziness becomes severe, persistent, or causes falls, contact your healthcare provider.

Use in Children

Consult a healthcare provider before giving prochlorperazine to a child or teenager who has:

  • Fever
  • Flu-like symptoms
  • Vomiting
  • Diarrhea

Compazine is not approved for use in children younger than 2 years of age or in children who weigh less than 20 pounds (9 kg).

Use in Older Adults With Dementia

Older adults with dementia-related psychosis who are treated with antipsychotic medications such as prochlorperazine may have an increased risk of death.

Compazine is not approved for the treatment of dementia-related psychosis.

Alcohol and Central Nervous System Depressants

Compazine should not be used in individuals who are:

  • In a comatose state
  • Under the influence of significant amounts of alcohol
  • Taking large amounts of central nervous system (CNS) depressants

Examples of CNS depressants include:

  • Alcohol
  • Barbiturates
  • Narcotic pain medications
  • Certain sedatives and sleeping pills

Combining these substances with Compazine may increase the risk of excessive sedation, breathing problems, and other serious side effects.

Tardive Dyskinesia

Long-term use of antipsychotic medications, including prochlorperazine, may increase the risk of tardive dyskinesia, a potentially irreversible movement disorder.

Symptoms may include:

  • Repetitive facial movements
  • Lip smacking
  • Tongue movements
  • Uncontrolled movements of the arms, legs, or body

If signs or symptoms of tardive dyskinesia develop, your healthcare provider may consider discontinuing the medication. However, in some cases, continued treatment may be necessary if the benefits outweigh the risks.

When to Contact Your Healthcare Provider

Contact your healthcare provider if you experience:

  • Severe dizziness or fainting
  • Uncontrolled muscle movements
  • Signs of an allergic reaction
  • Excessive drowsiness
  • Difficulty breathing
  • New or worsening symptoms

Regular monitoring can help ensure that Compazine is used safely and effectively while minimizing the risk of serious side effects.

Are There Any Drug Interactions I Should Be Aware Of?

Yes. Compazine may interact with a number of medications, which can increase the risk of side effects or affect how either medication works. Before starting treatment, be sure to tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, herbal supplements, and natural health products you use. Some medications that may interact with Compazine include monoamine oxidase inhibitors (MAOIs), levodopa, antifungal medications, lithium, diuretics (water pills), selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and antihistamines. Your healthcare provider can determine whether any dosage adjustments, medication changes, or additional monitoring are needed to help reduce the risk of drug interactions.

Is It Safe to Take Compazine During Pregnancy?

The safety of Compazine during pregnancy has not been fully established. Prochlorperazine has been classified as a Pregnancy Category C medication, meaning that there is limited information regarding its use during pregnancy. If you are pregnant, planning to become pregnant, or think you may be pregnant, discuss the potential risks and benefits of treatment with your healthcare provider before taking Compazine. Your healthcare provider can help determine whether the medication is appropriate for your situation.

What Should I Do If I Experience an Allergic Reaction to Compazine?

If you develop signs of an allergic reaction while taking Compazine (prochlorperazine), stop using the medication and seek immediate medical attention. Symptoms of an allergic reaction may include rash, hives, itching, swelling of the face, lips, tongue, or throat, difficulty breathing, or severe dizziness. A serious allergic reaction can be a medical emergency and may require prompt treatment, so contact emergency medical services or seek urgent care right away if these symptoms occur.

How Long Should I Use Compazine?

The length of treatment depends on the condition being treated, the severity of your symptoms, and how well you respond to the medication. In general, Compazine should be used for the shortest duration necessary to effectively control symptoms. Your healthcare provider will determine how long treatment should continue and may adjust your therapy based on your progress and any side effects you experience. Do not stop taking Compazine or change your dosage without first consulting your healthcare provider.

REVIEWS

Additional Information Book
Generic name:

Prochlorperazine

Formulation:

Tablet

Strength(s):

5mg, 10mg

Quantities Available:

84, 100

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Comprazine can I order at once from a Canadian pharmacy?

When ordering Comprazine (prochlorperazine) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Comprazine is available in 5 mg tablets. The maximum oral dose is usually 40 mg per day, divided into smaller doses taken throughout the day. For a 90-day supply, you would order 720 tablets (8 tablets per day x 90 days).

Do you sell prochlorperazine?

Yes, we offer prochlorperazine on our website at low prices. However, please note that you will need a valid prescription from your healthcare provider to purchase this medication. We require a prescription to dispense the medication safely. You can conveniently provide your prescription by mailing, faxing, or uploading it through your online account.

Do you offer shipping of Compazine (prochlorperazine) to the United States?

Yes, we ship Compazine (prochlorperazine) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Compazine (Prochlorperazine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Compazine (Prochlorperazine).