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Prescription Prescription Required FormationFormulation: Tablet


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Prescription Prescription Required FormationFormulation: Tablet

Loxapine Succinate

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Loxapac is a medication mainly used to treat the symptoms of schizophrenia, such as hallucinations, delusions, and disordered thinking. It may also be used to treat depression and bipolar disorder.

Loxapac contains an active ingredient called Loxapine Succinate. Loxapine is in a group of medications called conventional antipsychotics. It works by decreasing abnormal excitement in the brain.

Use and Dosage

Loxapine comes as a capsule to take by mouth usually taken two to four times a day. Try to take loxapine at around the same time every day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand. Take loxapine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

The recommended dosage of Loxapine Succinate can vary depending on the individual's age, medical condition, and the severity of their symptoms. Typically, the initial dose for adults is between 20 to 50 milligrams per day, divided into two to four doses per day, and gradually increased by the doctor over the course of 7 to 10 days until symptoms are well-controlled. The therapeutic and maintenance range is typically 60 to 100 mg daily, but some patients may require lower or higher doses. However, follow the dosage instructions provided by your doctor and do not adjust your dosage or stop taking the medication without consulting them first.

Loxapine may control your symptoms but will not cure your condition. It may take several weeks or longer for you to feel the full benefit of loxapine. Continue to take loxapine even if you feel well. Do not stop taking loxapine without talking to your doctor.

Side Effects

Common Side Effects of Loxapac (Loxapine Succinate):

  • Dizziness, problems with balance or walking
  • Swelling in your face
  • Itching or rash
  • Tremors, muscle twitching or stiffness
  • Numbness
  • Weakness
  • Blurred vision
  • Feeling restless or agitated
  • Nausea, vomiting, or constipation
  • Dry mouth, stuffy nose
  • Insomnia

Serious Side Effects of Loxapac (Loxapine Succinate):

  • A light-headed feeling (like you might pass out)
  • Agitation or trouble sleeping
  • Confusion
  • Slurred speech
  • Cough
  • Fast heart rate
  • Fast or uneven heartbeats
  • Fever
  • High fever
  • Little or no urinating
  • Mouth sores
  • Seizure (convulsions)
  • Severe constipation
  • Skin sores
  • Sore throat
  • Sweating
  • Tremors
  • Trouble breathing
  • Uncontrolled muscle movements in your arms, legs, or your face (ex: chewing, lip smacking, frowning, tongue movement, blinking, or eye movement)
  • Very stiff (rigid) muscles

Forms and Strength

Loxapac (Loxapine Succinate) is available in the following forms and strength:

Loxapac: Tablet

  • 2.5 mg
  • 10 mg
  • 25 mg


  • Loxapac should be used with caution in patients who have liver or kidney problems.
  • Loxapac may cause drowsiness or dizziness, which can affect the ability to operate machinery or drive a vehicle.
  • Loxapac may cause a decrease in blood pressure, so patients should be monitored regularly.
  • Loxapac may cause tardive dyskinesia, a condition where repetitive movements of the face and tongue occur.
  • Loxapac may cause neuroleptic malignant syndrome, a life-threatening condition that includes symptoms such as high fever, muscle rigidity, and rapid heartbeat.
  • Loxapac should be used with caution in patients who have a history of seizures or who are at risk for seizures.
  • Loxapac should not be used to treat behavioral problems in older adult patients who have dementia, as it may increase the risk of death.
  • Some medications or substances may interact with Loxapine Succonate, speak with a doctor before taking any other medications or supplements while on the medication.
  • Loxapac may cause weight gain and metabolic changes, such as high blood sugar and high cholesterol.
  • Loxapac should be used with caution in patients who have a history of heart disease or who are at risk for heart disease.
  • Loxapac may cause increased sensitivity to sunlight, so patients should avoid excessive exposure to sunlight or artificial UV rays.
  • Loxapac may cause respiratory depression, especially when used in combination with other medications that affect breathing.
  • Loxapac may cause sedation or confusion in elderly patients, and they may be at increased risk for falls or other accidents.
  • Loxapac should be used with caution in pregnant women or women who are breastfeeding, as its effects on the fetus or nursing infant are not known.
  • Loxapac may cause a reduction in white blood cell count, which can increase the risk of infections.

Frequently Asked Questions (FAQ)

How long does it take for Loxapac to work?

The time it takes for Loxapac to work can vary depending on the patient's condition and response to the medication.

Can Loxapac be stopped suddenly?

No, Loxapac should not be stopped suddenly as this can cause withdrawal symptoms such as nausea, vomiting, and insomnia.

Is it safe to drink alcohol while taking Loxapac?

No, don’t drink alcohol while taking Loxapac as it can increase the risk of side effects such as dizziness, drowsiness, and difficulty concentrating.

Can Loxapac be addictive?

Loxapac is not considered addictive, but it should still be used with caution as it can cause withdrawal symptoms.

How should Loxapac be stored?

Loxapac should be stored at room temperature, away from light and moisture. It should be kept out of the reach of children and pets.


Additional information

Generic name:

Loxapine Succinate




2.5mg, 10mg, 25mg

Quantities Available:



Additional Information Book

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Loxapac (Loxapine Succinate). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Loxapac (Loxapine Succinate).