Ludiomil (Maprotiline) Shopper Approved

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Prescription Prescription Required FormationFormulation: Tablet


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Ludiomil is a tetracyclic antidepressant (TeCA) used to treat depression. It can be used to treat major depressive disorder, depressive neurosis, manic depressive illness, or anxiety related to depression. It contains an active ingredient called Maprotiline. Maprotiline belongs to a class of medications called tetracyclic antidepressants. It works by affecting the balance of certain natural chemicals (neurotransmitters) in the brain.

Ludiomil is indicated for the treatment of depressive illness in patients with depressive neurosis (dysthymic disorder) and manic-depressive disorders. It is usually taken by mouth as a tablet, and the dosage can vary depending on the individual's condition and response to treatment.

Use and Dosage

Ludiomil is a medication that comes in tablet form and is taken by mouth as prescribed by a doctor, usually 1 to 3 times daily. If taking it once a day, take it at bedtime to reduce daytime sleepiness.

The dosage depends on the individual's medical condition and response to treatment. To minimize the risk of side effects, the doctor may start with a low dose and increase it gradually. Follow the doctor's instructions carefully and take the tablet regularly at the same time(s) each day for the best results. Don't change the dose or frequency of use without consulting the doctor.

Even if the symptoms improve, do not stop taking Ludiomil abruptly. Suddenly stopping the medication may worsen the underlying condition and cause withdrawal symptoms, such as mood changes, headache, and fatigue. To stop Ludiomil, the doctor may gradually reduce the dose over time. If new or worsening symptoms arise, inform the doctor promptly.

It may take up to 3 weeks before Ludiomil starts to have a noticeable effect. Notify the doctor if the condition persists or worsens despite treatment, or if thoughts of self-harm or suicide occur.

Side Effects

Common Side Effects of Ludiomil (Maprotiline):

  • Blurred vision
  • Constipation
  • Difficulty urinating
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Itching
  • Redness
  • Skin rash
  • Swelling

Serious Side Effects of Ludiomil (Maprotiline):

  • Breast enlargement in males and females
  • Confusion (especially in the elderly)
  • Constipation
  • Difficulty in urination
  • Fainting
  • Hallucinations (seeing, hearing, or feeling things that are not there)
  • Inappropriate secretion of milk in females
  • Irregular heartbeat (pounding, racing, skipping)
  • Nausea or vomiting
  • Seizures
  • Shakiness or trembling
  • Sore throat and fever
  • Swelling of testicles
  • Unusual excitement
  • Weight loss
  • Yellow eyes or skin

Forms and Strength

Ludiomil (Maprotiline) is available in the following forms and strength:

Ludiomil: Tablet

  • 25 mg
  • 75 mg


  • Ludiomil must be used with caution in individuals with a history of seizures or epilepsy.
  • The possibility of suicide in seriously depressed patients is a major concern while taking Ludiomil. Ludiomil must be used with caution in children with depression.
  • Ludiomil can cause sedation and impair mental and/or physical abilities required for tasks such as driving or operating machinery.
  • Individuals who are taking Ludiomil must inform their doctor of any pre-existing medical conditions such as liver or kidney disease.
  • Use of Ludiomil must be avoided or carefully monitored in individuals who have a history of heart disease, high blood pressure, or irregular heartbeats.
  • Ludiomil may cause agitation or restlessness.
  • Ludiomil may interact with certain medications, including MAO inhibitors and antipsychotic medications.
  • Individuals taking Ludiomil should avoid alcohol and other sedatives.
  • Ludiomil must not be discontinued suddenly, as it may cause withdrawal symptoms.

Frequently Asked Questions (FAQ)

Can Ludiomil be addictive?

Ludiomil is not considered to be addictive in the same way that drugs of abuse are, but it can lead to physical dependence if it is abruptly stopped after prolonged use.

How long does it take for Ludiomil to start working?

Ludiomil can take several weeks for Ludiomil to start working, and it may take up to 8 weeks for a full response to be seen.

Can I drink alcohol while taking Ludiomil?

Avoid alcohol while taking Ludiomil, as it can increase the risk of side effects such as drowsiness, dizziness, or impaired mental and physical abilities.


Additional information

Generic name:





25mg, 75mg

Quantities Available:

84, 90


Additional Information Book

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Ludiomil (Maprotiline). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Ludiomil (Maprotiline).