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Orilissa (Elagolix Sodium) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet

Orilissa

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Prescription Prescription Required FormationFormulation: Tablet

Elagolix Sodium

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Orilissa (active ingredient: elagolix) is a prescription medication used to manage moderate to severe pain caused by endometriosis in premenopausal women.

Endometriosis is a condition where tissue similar to the lining of the uterus grows outside the uterus. This tissue can respond to hormone changes during the menstrual cycle and may cause pain, inflammation, painful periods, pelvic pain, or pain during sex.

Endometriosis Pain

Orilissa helps reduce pain related to endometriosis by lowering certain hormone levels in the body. It may help with symptoms such as pelvic pain, painful menstrual cramps, and pain associated with endometriosis.

Orilissa does not cure endometriosis, but it may help make symptoms more manageable while it is being taken.

How Orilissa Works

Orilissa belongs to a class of medications called gonadotropin-releasing hormone antagonists, also known as GnRH antagonists.

It works by reducing signals from the brain that tell the ovaries to make estrogen and progesterone. Lowering these hormone levels can reduce stimulation of endometriosis tissue, which may help decrease inflammation and pain.

Because Orilissa lowers estrogen levels, it may also cause hormone-related side effects. Your healthcare provider will decide whether Orilissa is appropriate for you based on your symptoms, medical history, and treatment goals.

Orilissa helps reduce endometriosis-related pain by lowering certain hormone levels in the body, especially estrogen. Lower estrogen levels may help decrease the activity of endometriosis tissue and reduce pain symptoms.

Orilissa may help with common endometriosis symptoms such as:

  • Painful menstrual periods
  • Pelvic pain between periods
  • Pain during sex

Orilissa does not cure endometriosis, but it may help make symptoms more manageable while you are taking it.

Recommended Dosage

There are two common dosing options for Orilissa:

  • 150 mg once daily. This dose may be used for up to 24 months.
  • 200 mg twice daily. This higher dose may be used for up to 6 months.

The dose your healthcare provider chooses depends on your symptoms, medical history, liver function, risk of bone loss, and treatment goals. Treatment duration is limited because Orilissa lowers estrogen, which can reduce bone mineral density over time.

How to Take Orilissa

Take Orilissa by mouth exactly as prescribed. It may be taken with or without food.

If you take Orilissa once daily, take it at about the same time each day. If you take it twice daily, take one dose in the morning and one dose in the evening, as directed by your healthcare provider.

Important Reminder

Do not take more Orilissa than prescribed, and do not use it longer than recommended. Before starting Orilissa, tell your healthcare provider if you are pregnant, have liver problems, have osteoporosis, or have a history of bone loss.

Common Side Effects of Orilissa (elagolix):

  • Hot flashes
  • Night sweats
  • Headache
  • Nausea
  • Trouble sleeping
  • Missed or absent periods
  • Anxiety
  • Joint pain
  • Depression
  • Mood changes

Serious Side Effects of Orilissa (elagolix):

  • Bone loss
  • Mood changes and suicidal thoughts 
  • Liver-related symptoms:
    • Yellowing of the skin or eyes
    • Dark urine
    • Severe tiredness
    • Nausea
    • Vomiting
    • Pain in the upper right side of the stomach
  • Changes in menstrual bleeding

Orilissa (elagolix) is available in the following forms and strength:

Orilissa: Tablet

  • 150 mg
  • 200 mg

Before taking Orilissa, tell your healthcare provider about your medical history, pregnancy status, bone health, liver health, and all medications or supplements you take. Orilissa can affect hormone levels, so certain precautions are important before and during treatment.

Pregnancy

Do not take Orilissa if you are pregnant, trying to become pregnant, or think you may be pregnant. Orilissa may increase the risk of early pregnancy loss. If you think you may be pregnant while taking Orilissa, stop taking it and contact your healthcare provider right away.

Orilissa can also change your menstrual bleeding pattern, which may make it harder to recognize pregnancy. Your healthcare provider may recommend pregnancy testing before treatment and may discuss non-hormonal birth control options while you are taking Orilissa.

Bone Loss

Orilissa lowers estrogen levels, which can lead to decreased bone mineral density, also called bone loss. Bone loss may improve after stopping Orilissa, but complete recovery may not always occur. Because of this risk, your healthcare provider may limit how long you take Orilissa.

Tell your healthcare provider if you have osteoporosis, a history of bone loss, a family history of osteoporosis, or other risk factors for weak bones.

Liver Problems

Orilissa may not be safe for people with certain liver problems. It is not recommended for people with severe liver impairment. Tell your healthcare provider if you have liver disease or a history of abnormal liver tests before starting Orilissa.

Contact your healthcare provider if you develop symptoms such as yellowing of the skin or eyes, dark urine, severe tiredness, nausea, vomiting, or pain in the upper right side of the stomach.

Mood Changes

Orilissa may cause or worsen mood changes, depression, or suicidal thoughts. Tell your healthcare provider if you have a history of depression, mood disorders, or suicidal thoughts before taking Orilissa. Seek medical help right away if you notice new or worsening depression, anxiety, unusual mood changes, or thoughts of self-harm.

Drug Interactions

Orilissa can interact with certain medications. Some drugs may increase Orilissa levels in the body, while Orilissa may affect how other medications work. It should not be used with certain OATP1B1 inhibitors that can significantly increase elagolix exposure.

Before starting Orilissa, tell your healthcare provider about all prescription medications, over-the-counter medicines, vitamins, supplements, and herbal products you take.

Allergic Reactions

Do not take Orilissa if you have had a serious allergic reaction to elagolix or any ingredient in the medication. Get emergency medical help if you develop symptoms such as rash, hives, swelling of the face or throat, severe dizziness, or trouble breathing.

Important Reminder

Take Orilissa exactly as prescribed and do not use it longer than recommended. Your healthcare provider will choose the dose and treatment length based on your symptoms, liver function, bone health, and overall risk factors.

How long does Orilissa take to work?

Some people may notice improvement within the first few weeks, but response can vary. Continue taking Orilissa exactly as prescribed, and let your healthcare provider know if your pain does not improve or becomes worse.

Can Orilissa affect your period?

Yes. Orilissa can change your menstrual bleeding pattern. Your periods may become lighter, irregular, less frequent, or stop while taking the medication. Because of these changes, it may be harder to know if you are pregnant. Contact your healthcare provider if you think you may be pregnant.

Can you get pregnant while taking Orilissa?

Yes, pregnancy is still possible while taking Orilissa. However, Orilissa should not be used during pregnancy because it may increase the risk of early pregnancy loss. Your healthcare provider may recommend using effective non-hormonal birth control during treatment and for a short time after stopping Orilissa.

Can Orilissa cause bone loss?

Yes. Orilissa can lower estrogen levels, which may reduce bone mineral density over time. Because of this risk, treatment duration is limited. Tell your healthcare provider if you have osteoporosis, a history of bone loss, or risk factors for weak bones.

Can Orilissa be taken with other medications?

Orilissa may interact with certain medications. Before starting Orilissa, tell your healthcare provider about all prescription medicines, over-the-counter drugs, vitamins, supplements, and herbal products you take.

Can I stop taking Orilissa suddenly?

Do not stop taking Orilissa without speaking with your healthcare provider first. If you are having side effects or feel the medication is not helping, your provider can help decide whether to continue, adjust, or stop treatment safely.

REVIEWS

Additional Information Book
Generic name:

Elagolix Sodium

Formulation:

Tablet

Strength(s):

150mg, 200mg

Quantities Available:

28, 56, 84

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Orilissa can I order at once from a Canadian pharmacy?

When ordering Orilissa (elagolix) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time. This practice is common for prescription medications to ensure continuous treatment for chronic conditions without the need for frequent refills.

Here’s what you need to know:

Dosage and Quantity: Orilissa is commonly prescribed in dosages of 150 mg once daily or 200 mg twice daily for the treatment of endometriosis-associated pain.

For a 90-day supply:

  • For Orilissa 150 mg once daily, you would order 90 tablets (90 days x 1 tablet per day).
  • For Orilissa 200 mg twice daily, you would order 180 tablets (90 days x 2 tablets per day).

Do you sell elagolix?

No, we do not sell elagolix directly through our website. However, you can still enjoy competitive prices on Orilissa, which contains elagolix as an active ingredient. To purchase Orilissa, you will need a valid prescription from your healthcare provider. We require this to dispense the medication safely and legally. You can conveniently submit your prescription by mail, fax, or upload it through your online account.

Do you offer shipping of Orilissa (elagolix) to the United States?

Yes, we ship Orilissa (elagolix) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Orilissa (Elagolix Sodium). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Orilissa (Elagolix Sodium).