Femring (Estradiol) Shopper Approved

Prescription Prescription Required FormationFormulation: Vaginal Ring


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Prescription Prescription Required FormationFormulation: Vaginal Ring


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Femring is a prescription vaginal ring indicated for the treatment of moderate-to-severe vasomotor symptoms caused by menopause such as hot flashes, vaginal dryness, and atrophy. It contains estradiol acetate, a synthetic form of the hormone estrogen. Femring should be inserted intravaginally and worn for 90 days before being replaced with a new ring.

A femring ring is a soft, flexible ring that works by binding to estrogen receptors and increasing downstream effects, which helps reverse symptoms of menopause such as vaginal dryness. Femring also modulates the pituitary secretion of hormones like gonadotropins, follicle-stimulating hormones, and luteinizing hormones through negative feedback.

Uses and Dosage

The femring ring should be inserted intravaginally and worn for 90 days before being replaced with a new ring. Follow the specific instructions provided by your doctor and medication guide. Estrogens, including those in Femring, can increase the risk of endometrial cancer, so close clinical surveillance of all women taking this medication is necessary.

Step by step guide in inserting Femring:

  1. Wash & dry your hands before the ring insertion.
  2. Remove the vaginal ring from the packaging.
  3. Assume a position with which you are most comfortable.
  4. Using your thumb and index/pointer finger, press the sides of the vaginal ring together. Then, twist it into a figure-eight shape for easier insertion.
  5. Using your other hand, hold the folds of the skin around the vagina open.
  6. Put the tip of the ring into the opening of the vagina and use your pointer finger to push the folded ring gently into the vagina. Push it as high as you can.
  7. When you are done, wash your hands once again.

To remove Femring:

  1. Wash & dry your hands before you remove the ring.
  2. In a comfortable position, put a finger into your vagina and hook it through the vaginal ring.
  3. Gently pull the ring downwards until it comes out.
  4. Using toilet paper, discard the ring correctly.
  5. Wash your hands again after removing the vaginal ring.

Side Effect

Common Side Effects of Femring (Estradiol):

  • Bloating
  • Breakthrough bleeding
  • Breast pain or tenderness
  • Changes in your menstrual periods
  • Headache
  • Nausea
  • Stomach cramps
  • Swelling in your hands or feet
  • Thinning scalp hair
  • Vaginal itching or discharge
  • Vomiting
  • Weight gain

Serious Side Effects of Femring (Estradiol):

  • Breast lumps
  • Dark urine
  • Increased thirst or urination
  • Increased vaginal irritation or discharge
  • Mental or mood changes
  • Persistent nausea and vomiting
  • Severe abdominal pain
  • Signs of blood clots (chest pain, severe headache, unusual sweating, slurred speech, weakness on one side of the body, trouble breathing, sudden dizziness)
  • Toxic shock syndrome (high fever, sudden dizziness, fainting, unusual muscle pain, diarrhea, sunburn-like rash)
  • Unusual vaginal bleeding
  • Yellowish eyes and skin

Form and Strength

Femring (Estradiol) is available in the following forms and strength:

Femring: Capsule

  • 0.05mg/24h
  • 0.1mg/24h


  • Do not start using Femring if you have unusual vaginal bleeding; currently have or have had certain cancers, blood clots, or liver problems; had a stroke or heart attack; have been diagnosed with a bleeding disorder; are allergic to Femring or any of its ingredients; or think you might be pregnant.
  • Femring should not be used by women who are pregnant or breastfeeding.
  • Women who have or have had breast cancer or other estrogen-sensitive cancers should not use Femring.
  • Femring may increase the risk of blood clots, stroke, and heart attack, especially in women who smoke or have other risk factors for cardiovascular disease.
  • Women with liver disease or a history of liver disease should use Femring with caution, as it may worsen liver function.
  • Femring may interact with other medications, inform your doctor about all medications (prescription and over the counter) and supplements you are taking before using Femring.
  • Femring may cause side effects such as headache, breast tenderness, and vaginal bleeding. Talk to your doctor if you experience any uncomfortable symptoms while using Femring. Consult a healthcare professional for more specific information on using Femring, including its possible cautions and warnings.
  • Using estrogens with progestins may increase your chance of getting dementia, based on a study of women 65 years of age or older.
  • Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.
  • You and your healthcare provider should talk regularly about whether you still need treatment with Femring.
  • Estrogens increase the risk of gallbladder disease. Discontinue estrogen if loss of vision, pancreatitis, or liver problems occur. If you take thyroid medication, consult your healthcare provider, as use of estrogens may change the amount needed.

Frequently Asked Questions (FAQ)

Can Femring be used for birth control?

No, Femring is not approved for use as a method of birth control. It is used to treat menopausal symptoms only.

How long does it take for Femring to start working?

Femring may take a few weeks to start working. Your healthcare provider will monitor your symptoms and adjust your treatment as needed.

How often do I need to see my healthcare provider while using Femring?

Your healthcare provider may recommend regular check-ups while using Femring, especially if you have a history of endometrial cancer or other medical conditions. Follow their instructions carefully and report any unusual symptoms or side effects.

Can I swim or bathe while using Femring?

Yes, you can swim, bathe, and shower while using Femring. The ring is designed to stay in place and maintain its effectiveness during normal activities.

Can I use Femring with other medications?

Femring may interact with other medications, inform your healthcare provider about all the medicines you are taking, including over-the-counter drugs and supplements.

How do I dispose of used Femring rings?

To dispose of a used Femring, remove it from the vagina and throw it away in the trash. Do not flush it down the toilet.


Additional information

Generic name:



Vaginal Ring


0.05mg/24h, 0.1mg/24h

Quantities Available:



Additional Information Book

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Femring (Estradiol). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Femring (Estradiol).