Before taking Lotrel, tell your healthcare provider or pharmacist about your medical history, allergies, and all medications or supplements you are taking. Lotrel can cause certain side effects and may not be safe for everyone.
Dizziness and Drowsiness
Lotrel may cause dizziness, especially when you first start taking it or after your dose is changed. Alcohol and cannabis may make dizziness or drowsiness worse.
Until you know how Lotrel affects you, avoid driving, operating machinery, or doing activities that require alertness. Limit alcoholic beverages, and tell your healthcare provider if you use cannabis or cannabis-containing products.
Allergic Reactions
Before taking Lotrel, tell your healthcare provider if you are allergic to amlodipine, benazepril, other dihydropyridine calcium channel blockers, ACE inhibitors, or any other substances.
Lotrel may contain inactive ingredients that can cause allergic reactions or other problems in some people. Ask your pharmacist if you have concerns about the ingredients in your medication.
Dehydration and Lightheadedness
Lotrel may increase the risk of lightheadedness, especially if you become dehydrated. Sweating, diarrhea, or vomiting can cause fluid loss and may make dizziness or low blood pressure more likely.
If you have prolonged vomiting or diarrhea, contact your healthcare provider. Drink enough fluids to prevent dehydration unless your healthcare provider has told you to limit fluids.
Pregnancy Warning
Lotrel should not be used during pregnancy because it can harm or even cause death to a developing baby. If pregnancy is detected, Lotrel should be stopped as soon as possible under the direction of a healthcare provider.
Drugs like benazepril that affect the renin-angiotensin system can reduce fetal kidney function, especially during the second and third trimesters. This can increase the risk of serious injury or death in the fetus or newborn.
If you are pregnant, planning to become pregnant, or think you may be pregnant, contact your healthcare provider right away to discuss safer treatment options for blood pressure control.
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