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Lotensin HCT (benazepril and hydrochlorothiazide) is a prescription medication used to treat high blood pressure, also called hypertension.
It contains two active ingredients that work together to lower blood pressure:
By combining these two medications, Lotensin HCT helps reduce pressure inside the blood vessels and makes it easier for the heart to pump blood throughout the body.
Lowering high blood pressure can also reduce the risk of serious cardiovascular complications, including stroke, heart attack, and certain kidney problems.
Lotensin HCT may be prescribed when a single blood pressure medication does not provide adequate control or when a healthcare provider determines that combination treatment is appropriate.
Lotensin HCT helps control high blood pressure, but it does not permanently cure hypertension. Regular medication use, blood pressure monitoring, and healthy lifestyle habits are important for long-term management.
Lotensin HCT is used to help lower blood pressure in adults with hypertension.
Blood pressure is the force of circulating blood pushing against the walls of the arteries.
Arteries are blood vessels that carry oxygen-rich blood from the heart to different parts of the body.
Blood pressure is measured using two numbers.
Systolic blood pressure is the top number. It measures the pressure inside the arteries when the heart contracts and pumps blood.
Diastolic blood pressure is the bottom number. It measures the pressure inside the arteries when the heart relaxes between beats.
When blood pressure remains too high over time, it places additional strain on the heart and blood vessels.
This can gradually damage important organs, including the heart, brain, kidneys, and eyes.
High blood pressure is often called a silent condition because it usually does not cause noticeable symptoms.
Many people feel healthy even when their blood pressure is significantly elevated.
For this reason, regular blood pressure measurements are important for detecting hypertension and monitoring treatment.
Lotensin HCT combines two medications that lower blood pressure through different mechanisms.
Benazepril helps widen blood vessels by reducing the production of a hormone that causes them to tighten.
Hydrochlorothiazide helps the kidneys remove excess sodium and water, reducing the amount of fluid circulating through the bloodstream.
Together, these effects decrease pressure inside the arteries.
This combination can provide additional blood pressure reduction compared with using either ingredient alone in some patients.
Your healthcare provider will determine whether Lotensin HCT is appropriate based on your blood pressure readings, medical history, kidney function, and response to previous treatment.
Uncontrolled hypertension increases the risk of several serious health problems.
Over time, consistently elevated blood pressure can damage artery walls and make the heart work harder to circulate blood.
This may contribute to cardiovascular disease and damage to other organs.
By helping lower blood pressure, Lotensin HCT may reduce the risk of complications associated with hypertension.
A stroke occurs when blood flow to part of the brain is blocked or when a blood vessel in the brain ruptures.
High blood pressure is one of the most important modifiable risk factors for stroke.
Elevated pressure can damage blood vessels and increase the likelihood of blood clots or bleeding in the brain.
Controlling blood pressure helps reduce the risk of these complications.
Lotensin HCT contributes to stroke prevention by helping maintain blood pressure within the target range recommended by your healthcare provider.
High blood pressure makes the heart work harder to pump blood through the arteries.
Over time, this additional strain may contribute to heart enlargement, coronary artery disease, and other cardiovascular problems.
A heart attack occurs when blood flow to part of the heart muscle becomes blocked.
Lowering blood pressure reduces strain on the cardiovascular system and helps decrease the overall risk of heart-related complications.
However, Lotensin HCT does not directly dissolve blood clots or treat an ongoing heart attack.
Seek emergency medical attention if you experience severe chest pain, sudden shortness of breath, or other symptoms suggesting a heart attack.
The kidneys contain small blood vessels that filter waste products and excess fluid from the bloodstream.
High blood pressure can damage these delicate blood vessels over time.
This may gradually reduce the kidneys’ ability to filter blood properly.
Controlling hypertension can help reduce the risk of further kidney damage.
However, the effects of Lotensin HCT on kidney function require monitoring.
Benazepril can cause changes in kidney function and potassium levels, while hydrochlorothiazide may affect fluid and electrolyte balance.
Your healthcare provider may recommend regular blood tests to monitor kidney function and electrolytes during treatment.
Lotensin HCT contains two active ingredients that work in different ways to lower blood pressure.
Benazepril relaxes and widens blood vessels, while hydrochlorothiazide helps the kidneys remove excess sodium and water.
Together, these actions reduce the pressure inside the arteries and decrease the workload on the heart.
Benazepril Relaxes Blood Vessels
Benazepril belongs to a class of medications called angiotensin-converting enzyme (ACE) inhibitors.
The body naturally produces a hormone called angiotensin II, which causes blood vessels to narrow.
When blood vessels become narrower, the heart must work harder to push blood through them, causing blood pressure to rise.
Benazepril blocks the enzyme responsible for producing angiotensin II.
As a result, blood vessels relax and widen, allowing blood to flow more easily.
Benazepril also reduces the release of aldosterone, a hormone that encourages the body to retain sodium and water.
These combined effects help lower blood pressure and reduce strain on the cardiovascular system.
Hydrochlorothiazide Removes Excess Sodium and Water
Hydrochlorothiazide belongs to a class of medications called thiazide diuretics, commonly known as water pills.
It works by acting on the kidneys, which help regulate the body’s fluid and electrolyte balance.
Hydrochlorothiazide reduces the reabsorption of sodium and chloride in certain parts of the kidneys.
This causes more sodium and water to leave the body through urine.
As the amount of excess fluid in the bloodstream decreases, blood pressure may fall.
Over time, hydrochlorothiazide also helps lower blood pressure through additional effects on blood vessels.
Because it increases urine production, some people may notice that they need to urinate more frequently after taking Lotensin HCT.
The Two Ingredients Work Together
Benazepril and hydrochlorothiazide lower blood pressure through complementary mechanisms.
Benazepril relaxes blood vessels, while hydrochlorothiazide helps reduce excess fluid.
Combining these actions may produce greater blood pressure reduction than either medication alone.
This can be particularly useful for people whose blood pressure remains above their target despite treatment with a single medication.
However, both ingredients can affect kidney function and electrolyte levels, including potassium and sodium.
Your healthcare provider may recommend blood tests to monitor these levels during treatment.
Some people require more than one medication to control high blood pressure.
Hypertension involves several processes, including blood vessel narrowing, fluid balance, kidney function, and hormone regulation.
Because one medication may not adequately address all these factors, combination treatment may be necessary.
Lotensin HCT provides two blood pressure medications in a single tablet.
This can make treatment more convenient for people who require both benazepril and hydrochlorothiazide.
However, Lotensin HCT is not intended as the initial treatment for hypertension according to its U.S. prescribing information.
It is generally considered when a healthcare provider determines that combination therapy is necessary and appropriate.Â
Lotensin HCT begins lowering blood pressure after you take it, although the timing and degree of response vary.
Benazepril may begin reducing blood pressure within approximately one hour, with its effects becoming more noticeable over the following hours.
Hydrochlorothiazide generally begins increasing urine production within about two hours after a dose.
The combined blood pressure-lowering effect can last approximately 24 hours, depending on the prescribed dose and individual response.
However, determining whether the medication is providing adequate long-term blood pressure control may require several weeks of treatment and follow-up measurements.
Because hypertension usually does not cause noticeable symptoms, you may not feel different even when Lotensin HCT is working.
Your healthcare provider may recommend checking your blood pressure regularly at home.
Continue taking Lotensin HCT exactly as prescribed, even if you feel well or your blood pressure readings improve.Â
Lotensin HCT should be taken only as prescribed by your healthcare provider.
The medication may cause dizziness or lightheadedness, particularly when treatment begins or the dose is adjusted.
Hydrochlorothiazide can also increase urination and affect the body’s electrolyte balance.
Your healthcare provider may recommend monitoring blood pressure, kidney function, sodium, and potassium levels during treatment.
Lotensin HCT must not be used during pregnancy because medications that affect the renin-angiotensin system, including benazepril, can cause serious harm to a developing baby.
It may also cause angioedema, a potentially life-threatening reaction involving swelling of the face, lips, tongue, or throat.
Seek emergency medical attention if you experience facial or throat swelling or difficulty breathing.
Lotensin HCT is a prescription combination medication used to treat high blood pressure, also called hypertension.
It contains two active ingredients that work together to lower blood pressure. Benazepril helps relax and widen blood vessels, while hydrochlorothiazide helps the kidneys remove excess sodium and water through urine.
Lotensin HCT comes in tablet form and is usually taken once daily by mouth, with or without food.
Swallow the tablet with water and follow the dosage instructions provided by your healthcare provider.
Try to take Lotensin HCT at approximately the same time every day. Maintaining a consistent routine helps you remember your medication and supports regular blood pressure control.
Because hydrochlorothiazide increases urine production, taking Lotensin HCT in the morning may be more convenient and may reduce the need to urinate during the night.
Continue taking Lotensin HCT even if you feel well. High blood pressure often causes no noticeable symptoms, so regular medication use is important for preventing long-term complications.
The appropriate dosage of Lotensin HCT depends on your blood pressure readings, medical history, kidney function, and response to treatment.
Lotensin HCT combines an angiotensin-converting enzyme (ACE) inhibitor with a thiazide diuretic.
Your healthcare provider may prescribe this combination when treatment with one blood pressure medication does not adequately control your blood pressure.
The medication is available in different strengths containing varying amounts of benazepril and hydrochlorothiazide.
Your healthcare provider will select an appropriate strength and may adjust your dosage based on your response.
Blood pressure, kidney function, and electrolyte levels may need to be monitored during treatment.
Electrolytes are minerals in the blood, including sodium and potassium, that help regulate fluid balance, nerve activity, and muscle function.
Do not increase, decrease, or stop taking Lotensin HCT without consulting your healthcare provider.
Lotensin HCT may be taken with or without food.
You can take the tablet before, during, or after a meal, depending on what is most convenient for you.
Food does not significantly interfere with its intended blood pressure-lowering effects.
If you experience mild stomach discomfort after taking the medication, taking it with food may help.
Swallow your prescribed dose with water and try to take it at the same time each day.
Because hydrochlorothiazide increases urine production, many patients prefer taking Lotensin HCT in the morning.
If your healthcare provider has recommended a different dosing time, follow their instructions.
Taking Lotensin HCT consistently helps maintain regular blood pressure control.
High blood pressure develops when the force of blood pushing against artery walls remains elevated over time.
Lotensin HCT helps lower this pressure through two complementary actions.
Benazepril relaxes blood vessels by reducing the production of angiotensin II, a hormone that causes blood vessels to narrow.
Hydrochlorothiazide helps remove excess sodium and water through the kidneys, reducing fluid volume and supporting lower blood pressure.
Taking the medication at consistent times helps you maintain your prescribed treatment routine.
Missing doses or frequently changing your schedule may reduce the effectiveness of treatment.
Consider setting a daily reminder or taking your tablet as part of your morning routine.
It is important to maintain appropriate hydration while taking Lotensin HCT.
Hydrochlorothiazide is a diuretic, sometimes called a water pill, that increases the amount of sodium and water removed through urine.
This effect helps lower blood pressure but can also increase the risk of dehydration, particularly during hot weather, illness, or prolonged physical activity.
Dehydration occurs when the body loses more fluid than it takes in.
Possible symptoms include increased thirst, dry mouth, dizziness, weakness, and reduced urination.
Drink fluids regularly according to your healthcare provider’s recommendations.
However, do not increase your fluid intake excessively without medical advice, especially if you have heart failure, kidney disease, or another condition requiring fluid restrictions.
If your healthcare provider has recommended limiting fluids, continue following those instructions.
Contact your healthcare provider if you experience persistent vomiting, severe diarrhea, excessive sweating, or difficulty drinking enough fluids.
These conditions may increase the risk of dehydration, low blood pressure, and changes in kidney function.
Lotensin HCT begins lowering blood pressure after the first dose, but its full treatment effect may take several weeks.
Benazepril may begin reducing blood pressure within approximately one hour, with peak effects occurring two to four hours after taking the medication.
Hydrochlorothiazide generally begins increasing urine production within about two hours, with its diuretic effect lasting approximately six to twelve hours.
However, the combined blood pressure-lowering response develops over time.
Your healthcare provider may reassess your blood pressure after two to three weeks and adjust the dosage if necessary.
Because high blood pressure usually does not cause noticeable symptoms, you may not feel different even when the medication is working.
The best way to determine whether Lotensin HCT is effective is through regular blood pressure measurements.
Your healthcare provider may recommend checking your blood pressure at home and recording your readings.
Continue taking Lotensin HCT regularly, even if your blood pressure improves. Stopping treatment without medical advice may cause your blood pressure to rise again.Â
Lotensin HCT is approved for treating hypertension, not specifically for treating congestive heart failure.
Congestive heart failure occurs when the heart cannot pump blood effectively enough to meet the body’s needs. This may cause shortness of breath, fatigue, swelling in the legs, or fluid buildup.
Some medications that belong to the same classes as the ingredients in Lotensin HCT are used in heart failure management.
For example, ACE inhibitors may help reduce strain on the heart, while diuretics can help manage excess fluid.
However, this does not mean Lotensin HCT is an approved or appropriate heart failure treatment for every patient.
The original statement suggesting that Lotensin HCT takes several weeks or months to treat congestive heart failure should therefore be distinguished from its approved use for high blood pressure.
If you have heart failure, your healthcare provider will determine which medications and dosages are appropriate for your condition.
Lotensin HCT may interact with certain cholesterol-lowering medications, including cholestyramine and colestipol.
These medications belong to a class called bile acid sequestrants. They work in the digestive system by binding bile acids and helping remove them from the body.
However, they may also bind hydrochlorothiazide and reduce its absorption.
This can make Lotensin HCT less effective at lowering blood pressure.
If you take cholestyramine or colestipol, the recommended timing is to take Lotensin HCT at least four hours before or four to six hours after these medications.
For example, if you take Lotensin HCT at 8:00 AM, you should generally wait until at least 12:00 PM before taking cholestyramine or colestipol.
Your pharmacist can help you organize your medication schedule to reduce the likelihood of interactions.
Do not stop taking your cholesterol medication or change your prescribed doses without consulting your healthcare provider.Â
If you forget to take Lotensin HCT, take the missed dose as soon as you remember unless it is almost time for your next scheduled dose.
If your next dose is approaching, skip the missed dose and continue with your regular schedule.
Do not take two doses at the same time to make up for a missed dose.
Taking extra medication may cause your blood pressure to drop too low or increase the risk of dehydration and electrolyte imbalances.
If you frequently forget to take Lotensin HCT, consider using a medication reminder or incorporating your tablet into your morning routine.
Contact your healthcare provider or pharmacist if you are unsure how to manage a missed dose.
Do not stop taking Lotensin HCT simply because your blood pressure readings have returned to a healthy range.
High blood pressure is usually a long-term condition that requires ongoing management.
Lotensin HCT helps control blood pressure while you are taking it, but it does not permanently eliminate the underlying causes of hypertension.
Stopping treatment may allow your blood pressure to rise again, increasing the risk of cardiovascular complications.
Your healthcare provider may adjust your medication if your blood pressure becomes consistently too low, you experience side effects, or your treatment needs change.
Regular monitoring helps determine whether your current dose remains appropriate.
Lotensin HCT may cause dizziness, especially when starting treatment or increasing the dose.
Stand up slowly from a sitting or lying position to reduce the risk of lightheadedness.
Because hydrochlorothiazide affects fluid and electrolyte balance, your healthcare provider may recommend regular blood tests to monitor kidney function, potassium, and sodium levels.
Do not use potassium supplements or potassium-containing salt substitutes unless your healthcare provider recommends them. Benazepril can increase potassium levels, even though hydrochlorothiazide may lower them.
Lotensin HCT must not be used during pregnancy. Benazepril can cause serious harm to a developing baby. Contact your healthcare provider immediately if you become pregnant while taking this medication.
Another serious potential side effect is angioedema, which can cause swelling of the lips, face, tongue, or throat.
Seek emergency medical attention if you develop facial or throat swelling or difficulty breathing.
Contact your healthcare provider if you experience persistent dizziness, unusual weakness, excessive thirst, muscle cramps, or changes in urination.
These symptoms may indicate low blood pressure, dehydration, or changes in electrolyte levels.
Seek prompt medical advice if you develop persistent vomiting or diarrhea because these conditions can increase your risk of dehydration and kidney problems.
Seek emergency medical attention if you experience difficulty breathing, swelling of the tongue or throat, fainting with severe symptoms, or signs of a serious allergic reaction.
Lotensin HCT (Benazepril/Hctz) is available in the following forms and strength:
Lotensin HCT is a prescription combination medication used to treat high blood pressure, also called hypertension.
It contains two active ingredients that work together to lower blood pressure. Benazepril is an angiotensin-converting enzyme (ACE) inhibitor that helps relax blood vessels, while hydrochlorothiazide is a thiazide diuretic that helps the kidneys remove excess sodium and water through urine.
Although Lotensin HCT can help control blood pressure and reduce the risk of cardiovascular complications, it may cause serious side effects in certain patients.
Before starting treatment, tell your healthcare provider about your medical history, allergies, kidney and liver conditions, and all medications you currently take.
Lotensin HCT must not be used during pregnancy because it can cause serious harm or death to a developing baby.
Benazepril affects the renin-angiotensin system, which helps regulate blood pressure, fluid balance, and kidney function.
This system also plays an important role in fetal kidney development.
Exposure to medications that affect the renin-angiotensin system, particularly during the second and third trimesters of pregnancy, can interfere with the development and function of a baby’s kidneys.
Possible complications include reduced fetal kidney function, decreased amniotic fluid, abnormal lung development, skeletal abnormalities, and fetal or newborn death.
Amniotic fluid is the liquid that surrounds and protects a developing baby during pregnancy.
Very low amniotic fluid levels can interfere with normal fetal growth and development.
If you become pregnant while taking Lotensin HCT, stop taking the medication and contact your healthcare provider immediately.
Your healthcare provider will recommend an alternative blood pressure treatment that is appropriate during pregnancy.
If you are planning to become pregnant, discuss your medication options with your healthcare provider before conception.
The official prescribing information includes a boxed warning about fetal toxicity.Â
Lotensin HCT may cause a serious reaction called angioedema.
Angioedema is sudden swelling that develops beneath the skin or in deeper tissues.
It commonly affects the face, lips, tongue, throat, or other parts of the body.
Benazepril belongs to a class of medications called ACE inhibitors, which can increase the activity of a substance called bradykinin.
Bradykinin affects blood vessels and may contribute to swelling in susceptible individuals.
Angioedema can occur at any time during treatment, even after a person has taken an ACE inhibitor without problems for months or years.
Symptoms may include swelling of the lips, face, tongue, or throat, difficulty swallowing, or trouble breathing.
If swelling affects the airway, it can become life-threatening.
Lotensin HCT must not be used by patients with a history of angioedema, whether or not it was caused by a previous ACE inhibitor. This is a contraindication, not simply a precaution.
If you develop swelling of your face, tongue, or throat, stop taking Lotensin HCT and seek emergency medical attention.
Do not take another dose unless a healthcare professional has assessed the reaction and advised you on appropriate treatment.Â
Tell your healthcare provider if you have kidney disease or reduced kidney function before taking Lotensin HCT.
The kidneys help filter waste products from the blood, regulate fluid balance, and maintain normal electrolyte levels.
Both benazepril and hydrochlorothiazide can affect kidney function.
Benazepril changes blood flow and pressure within the kidneys by blocking the effects of angiotensin II.
Hydrochlorothiazide increases the removal of sodium and water through urine.
In some patients, these effects may cause a temporary rise in blood creatinine levels or worsen existing kidney impairment.
Creatinine is a waste product measured through blood tests to help evaluate kidney function.
People with significant kidney disease may require closer monitoring or a different blood pressure medication.
Lotensin HCT must not be used in patients with anuria, a condition in which the kidneys cannot produce urine.
Your healthcare provider may recommend blood tests before and during treatment to monitor kidney function and electrolyte levels.
Contact your healthcare provider if you experience significantly reduced urination, unusual weakness, swelling, or persistent dizziness.
Lotensin HCT should be used cautiously in patients with renal artery stenosis.
Renal artery stenosis occurs when one or both arteries supplying blood to the kidneys become narrowed.
These arteries deliver oxygen-rich blood to the kidneys, allowing them to filter waste products and regulate blood pressure.
When blood flow to the kidneys becomes restricted, the kidneys may depend more heavily on the renin-angiotensin system to maintain normal filtration.
Benazepril blocks part of this system.
Although this action helps lower blood pressure, it can also reduce filtration pressure within the kidneys.
In patients with renal artery stenosis, particularly when both kidneys are affected or only one functioning kidney is present, this may cause kidney function to worsen.
Your healthcare provider may recommend checking blood creatinine and potassium levels during the first few weeks of treatment.
In some cases, treatment may need to be adjusted or discontinued if kidney function deteriorates significantly.
Tell your healthcare provider if you have ever been diagnosed with renal artery stenosis or have received treatment for narrowed kidney arteries.Â
Lotensin HCT may increase the risk of dehydration because it contains hydrochlorothiazide, a diuretic commonly called a water pill.
Hydrochlorothiazide helps the kidneys remove excess sodium and water through urine.
This action lowers blood pressure but can also cause the body to lose too much fluid.
Dehydration occurs when the body loses more fluid than it replaces.
Possible symptoms include increased thirst, dry mouth, dizziness, weakness, dark urine, and reduced urination.
The risk of dehydration may increase during hot weather, prolonged physical activity, or illness involving vomiting or diarrhea.
Dehydration can also increase the risk of low blood pressure and kidney problems while taking Lotensin HCT.
Drink fluids regularly according to your healthcare provider’s recommendations.
However, do not increase your fluid intake excessively if you have heart failure, kidney disease, or another condition requiring fluid restrictions.
If you experience persistent vomiting, severe diarrhea, or difficulty drinking enough fluids, contact your healthcare provider.
Your medication may need to be temporarily reviewed during illnesses that cause significant fluid loss.
Lotensin HCT may sometimes lower blood pressure too much, causing a condition called hypotension.
Hypotension occurs when blood pressure falls below the level needed to maintain adequate circulation.
Possible symptoms include dizziness, lightheadedness, blurred vision, unusual weakness, or fainting.
These effects may be more noticeable when you first start treatment or after your dosage is increased.
People who are dehydrated, taking several blood pressure medications, or following strict fluid restrictions may have a greater risk of developing low blood pressure.
One form is orthostatic hypotension, which occurs when blood pressure drops after standing up from a sitting or lying position.
To reduce dizziness, stand up slowly and allow yourself time to regain your balance before walking.
Contact your healthcare provider if you experience frequent dizziness or unusually low blood pressure readings.
Seek urgent medical attention if you faint, develop severe weakness, or experience symptoms suggesting dangerously low blood pressure.
Lotensin HCT may affect the levels of important minerals in your blood, including sodium and potassium.
These minerals are called electrolytes. They help regulate fluid balance, nerve activity, muscle contractions, and normal heart function.
Hydrochlorothiazide may cause the body to lose excessive amounts of sodium or potassium through urine.
Benazepril, on the other hand, may increase potassium levels by reducing aldosterone activity.
Because the two ingredients affect potassium differently, blood potassium levels may become too high or too low depending on your kidney function, other medications, and overall health.
Symptoms of electrolyte imbalances may include muscle cramps, weakness, unusual fatigue, nausea, or irregular heartbeats.
Severe electrolyte disturbances can be dangerous.
Your healthcare provider may recommend regular blood tests to monitor potassium, sodium, and kidney function.
Do not take potassium supplements or potassium-containing salt substitutes unless your healthcare provider recommends them.
Tell your healthcare provider if you have liver disease or a history of liver problems before taking Lotensin HCT.
The liver plays an important role in processing medications and maintaining normal metabolic functions.
Patients with significant liver impairment may be more sensitive to changes in fluid and electrolyte balance caused by hydrochlorothiazide.
These changes can be particularly concerning in patients with advanced liver disease.
In addition, rare cases of serious liver injury have been associated with ACE inhibitors, including benazepril.
Possible warning signs include unusual fatigue, persistent nausea, loss of appetite, dark urine, abdominal pain, and yellowing of the skin or eyes.
Yellowing of the skin or eyes is called jaundice and may indicate liver dysfunction.
Your healthcare provider may recommend additional monitoring if you have a history of liver disease.
Stop taking Lotensin HCT and seek prompt medical evaluation if you develop jaundice or other symptoms suggesting serious liver injury.
Older adults may be more sensitive to certain effects of Lotensin HCT.
As people age, kidney function may gradually decline, and the body may become less efficient at maintaining normal fluid and electrolyte balance.
Older adults are also more likely to take several medications for different medical conditions.
These factors may increase the risk of dizziness, dehydration, electrolyte disturbances, and changes in kidney function.
Some patients may experience orthostatic hypotension, which causes blood pressure to decrease when standing.
This may increase the risk of falls, particularly in people with balance problems or reduced mobility.
Your healthcare provider may recommend starting with an appropriate dose and monitoring your blood pressure, kidney function, and electrolyte levels.
Do not change your Lotensin HCT dose based on age alone. Your healthcare provider will determine whether adjustments are necessary.
Lotensin HCT may interact with other medications and supplements.
Some interactions may increase the risk of low blood pressure, kidney problems, or abnormal electrolyte levels.
Important medications include:
Lotensin HCT must also not be taken together with medications containing a neprilysin inhibitor, such as sacubitril/valsartan, because of the increased risk of angioedema.
A separation period of at least 36 hours is required when switching between these treatments.
Tell your healthcare provider about all prescription medications, over-the-counter drugs, vitamins, herbal supplements, and salt substitutes you use.
Do not begin a new medication or supplement without checking for potential interactions.Â
Lotensin HCT may cause allergic reactions in some patients.
Do not take Lotensin HCT if you are allergic to benazepril, another ACE inhibitor, hydrochlorothiazide, or certain sulfonamide-derived medications.
The medication may also be unsuitable for people who have previously experienced severe allergic reactions to related drugs.
Possible symptoms include itching, hives, a skin rash, or swelling.
Severe reactions may cause difficulty breathing, swelling of the tongue or throat, or a sudden drop in blood pressure.
Tell your healthcare provider if you have a history of medication allergies or bronchial asthma, as certain hypersensitivity reactions may be more likely.
Stop taking Lotensin HCT and seek emergency medical attention if you experience difficulty breathing, swelling of the face or throat, or other symptoms of a severe allergic reaction.
Lotensin HCT may not adequately control blood pressure in every patient.
The response to treatment depends on factors such as the severity of hypertension, kidney function, other medical conditions, and the medications being used.
Some patients may require a dosage adjustment or an additional blood pressure medication to reach their recommended target.
Others may experience side effects that make a different treatment more appropriate.
Your healthcare provider may recommend measuring your blood pressure regularly at home.
Keeping a record of your readings can help determine whether treatment is working.
Do not increase your dose or take extra tablets if your blood pressure remains high.
Contact your healthcare provider if your readings consistently remain above the target they have recommended.
Because high blood pressure usually causes no noticeable symptoms, continue taking Lotensin HCT even if you feel well.
Contact your healthcare provider if you experience persistent dizziness, excessive thirst, unusual weakness, muscle cramps, reduced urination, or worsening swelling.
These symptoms may indicate dehydration, low blood pressure, electrolyte disturbances, or kidney problems.
Seek prompt medical attention if you develop yellowing of the skin or eyes, persistent vomiting or diarrhea, or other symptoms suggesting a serious complication.
Seek emergency medical attention if you experience swelling of the face, tongue, or throat, difficulty breathing, severe chest pain, or signs of a stroke.
Stroke symptoms may include sudden weakness on one side of the body, difficulty speaking, facial drooping, or sudden vision changes.
No. Lotensin HCT must not be taken during pregnancy because it can cause serious harm or death to a developing baby. Lotensin HCT contains benazepril, an angiotensin-converting enzyme (ACE) inhibitor that helps lower blood pressure by relaxing blood vessels. ACE inhibitors affect the renin-angiotensin system, which plays an important role in regulating blood pressure and supporting fetal kidney development. Taking benazepril during pregnancy, particularly during the second and third trimesters, may interfere with normal fetal kidney function. This can cause serious complications, including reduced amniotic fluid, abnormal lung development, kidney damage, and fetal or newborn death. Amniotic fluid is the liquid that surrounds and protects a developing baby during pregnancy. If you become pregnant while taking Lotensin HCT, stop taking the medication and contact your healthcare provider immediately. Your healthcare provider will recommend another blood pressure medication that is safer to use during pregnancy. If you are planning to become pregnant, discuss your treatment options before conception. Do not stop managing your high blood pressure altogether, as uncontrolled hypertension can also cause serious complications during pregnancy.
If you forget to take a dose of Lotensin HCT, take it as soon as you remember unless it is almost time for your next scheduled dose. If your next dose is approaching, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a missed dose. Taking extra medication may cause your blood pressure to drop too low, resulting in dizziness, lightheadedness, weakness, or fainting. Because Lotensin HCT contains hydrochlorothiazide, taking an additional dose may also increase urination and the risk of dehydration or electrolyte imbalances. Electrolytes are minerals, such as sodium and potassium, that help regulate fluid balance, nerve function, and muscle activity. To help you remember your medication, try taking Lotensin HCT at approximately the same time each day. Many people prefer taking it in the morning because hydrochlorothiazide increases urine production. If you frequently forget doses, consider setting a phone reminder or using a medication organizer. Contact your healthcare provider or pharmacist if you are unsure how to manage a missed dose.
Lotensin HCT begins lowering blood pressure after the first dose, but its full effect may take several weeks. The medication contains two active ingredients that work together to control hypertension. Benazepril helps relax and widen blood vessels, allowing blood to flow more easily. Hydrochlorothiazide helps the kidneys remove excess sodium and water through urine, reducing fluid volume and blood pressure. Benazepril may begin lowering blood pressure within approximately one hour, with its greatest effect from an individual dose usually occurring within two to four hours. Hydrochlorothiazide generally begins increasing urine production within about two hours. However, the full blood pressure-lowering benefit of Lotensin HCT may take approximately two to three weeks, depending on your dosage and individual response. Your healthcare provider may recommend monitoring your blood pressure at home to determine how well the medication is working. Because high blood pressure often causes no noticeable symptoms, you may not feel different even when your blood pressure improves. Continue taking Lotensin HCT exactly as prescribed, even if you feel well. Do not increase your dose if your blood pressure remains elevated. Contact your healthcare provider to determine whether a treatment adjustment is necessary.
Alcohol may increase certain side effects of Lotensin HCT, particularly dizziness, lightheadedness, and low blood pressure. Lotensin HCT lowers blood pressure by relaxing blood vessels and helping the kidneys remove excess sodium and water. Alcohol can also affect blood vessel function and may temporarily lower blood pressure. When combined, these effects can make some people more likely to experience hypotension, which means blood pressure becomes lower than normal. Symptoms may include dizziness, weakness, blurred vision, or fainting. Alcohol may also contribute to dehydration, particularly when consumed in large amounts. This is important because hydrochlorothiazide increases fluid loss through urine. The risk of dizziness or dehydration may be greater when you first start Lotensin HCT, after a dosage increase, or during hot weather. It is best to avoid alcohol until you know how Lotensin HCT affects you. If you choose to drink alcohol, discuss an appropriate amount with your healthcare provider, particularly if you have liver disease, kidney problems, or difficulty maintaining stable blood pressure. Avoid driving or operating machinery if you experience dizziness or reduced alertness. Contact your healthcare provider if you develop persistent lightheadedness, fainting, or other concerning symptoms.
Yes. Lotensin HCT can be taken with or without food. You may take the tablet before, during, or after a meal, depending on what is most convenient for you. Food does not significantly interfere with the medication’s intended blood pressure-lowering effects. If you experience mild stomach discomfort, taking the tablet with food may help. Swallow your prescribed dose with water and try to take it at approximately the same time every day. Because Lotensin HCT contains hydrochlorothiazide, a diuretic that increases urine production, taking the medication in the morning may be more convenient. This may help reduce the need to urinate during the night. If your healthcare provider has prescribed a different dosing schedule, follow their instructions. Maintain appropriate fluid intake while taking Lotensin HCT, but do not drink excessive amounts of water if you have heart failure, kidney disease, or another condition requiring fluid restrictions. Taking Lotensin HCT consistently is more important than whether you take it with a meal. Continue following your prescribed schedule to maintain effective blood pressure control.
| Generic name: | Benazepril/Hctz |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 10/12.5mg, 20/12.5mg, 20/25mg |
| Quantities Available: | 84, 90 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Lotensin HCT (benazepril/hctz) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Lotensin HCT is commonly prescribed in dosages of 10 mg/12.5 mg, taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).
Yes, we sell benazepril/hctz on our website. You can enjoy low prices when you order through us. To purchase benazepril/hctz, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You can submit your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Lotensin HCT (benazepril/hctz) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Lotensin HCT (Benazepril/Hctz). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Lotensin HCT (Benazepril/Hctz).
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