Monopril HCTZ (Fosinopril Hctz)

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Monopril HCTZ Brand
Dosage Quantity & Price
Fosinopril Hctz (Generic alternate to Monopril HCTZ) Generic

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Table of contents:

Monopril HCT (fosinopril sodium-hydrochlorothiazide) is a combination ACE (angiotensin converting enzyme) inhibitor and diuretic used to treat hypertension (high blood pressure). It can be used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease and to treat edema caused by using certain medications including estrogen and corticosteroids.

Fosinopril belongs to a class of drugs known as ACE inhibitors. It works by relaxing blood vessels so that blood can flow more easily.

Use and Dosage

Monopril hctz is available in the form of a tablet, which can be taken orally with or without food, as recommended by your doctor, usually once a day. Taking this medication too close to bedtime may lead to waking up to urinate, so it is best to take it at least 4 hours before bedtime. If you have any concerns regarding the timing of taking the medication, consult your doctor or pharmacist.

The dosage of monopril hctz varies depending on your response to treatment and medical condition. Taking antacids containing aluminum or magnesium or certain cholesterol-lowering drugs such as bile acid-binding resins can reduce the absorption of monopril hctz; therefore, it is best to take them at least 2 or 4-6 hours apart from this medication, respectively.

Taking monopril hctz regularly, preferably at the same time each day, will ensure maximum benefit from the medication. It may take several weeks before you experience the full benefit of this medication. Even if you feel well, continue taking monopril hctz as prescribed. People with high blood pressure usually do not exhibit any symptoms of illness. If your routine blood pressure readings remain high or increase, inform your doctor immediately.

Side Effects

Common Side Effects of Monopril HCTZ (Fosinopril Hctz):

  • Diarrhea
  • Frequent urination
  • Hair loss
  • Headache
  • Loss of appetite

Serious Side Effects of Monopril HCTZ (Fosinopril Hctz):

  • Blisters or peeling skin
  • Changes in vision, eye pain, or swelling or redness in or around the eye
  • Difficulty breathing or swallowing
  • Dry mouth; thirst; nausea; vomiting; weakness, tiredness; drowsiness; restlessness; confusion; muscle weakness, pain, or cramps; fast heartbeat and other signs of dehydration and electrolyte imbalance
  • Fever, sore throat, chills, and other signs of infection
  • Hives
  • Itching
  • Joint pain or swelling
  • Ongoing pain that begins in the stomach area, but may spread to the back
  • Rash
  • Unusual bleeding or bruising

Forms and Strength

Monopril HCTZ (Fosinopril Hctz) is available in the following forms and strength:

Monopril HCTZ: Tablet

  • 10/12.5mg
  • 20/12.5mg


  • Do not take Monopril HCT if you are allergic to fosinopril, hydrochlorothiazide, or any other ingredients in the medication.
  • Inform your healthcare provider if you have any history of kidney disease, liver disease, heart disease, or diabetes before taking Monopril HCT.
  • Monopril HCT can cause low blood pressure, especially if you are dehydrated or have low salt levels in your body. Stay well hydrated when taking this medication.
  • Monopril HCT can interact with other medications, including nonsteroidal anti-inflammatory drugs (NSAIDs) and potassium-sparing diuretics. Make sure to inform your healthcare provider about all medications you are currently taking.
  • Monopril HCT can cause fetal harm if taken during pregnancy. Talk to your healthcare provider if you are pregnant or planning to become pregnant while taking Monopril HCT.
  • Monopril HCT can pass into breast milk and may harm a nursing infant. Talk to your healthcare provider before breastfeeding while taking Monopril HCT
  • Monopril HCT can cause dizziness or lightheadedness, especially when getting up from a sitting or lying position. To reduce the risk of falls, it is important to get up slowly and steady yourself.
  • Monopril HCT can increase the risk of hyperkalemia (elevated levels of potassium in the blood), especially in people with kidney problems. Periodic blood tests may be necessary to monitor potassium levels.
  • Monopril HCT can cause increased sensitivity to sunlight or ultraviolet rays. Wear protective clothing and use sunscreen when outdoors.
  • Monopril HCT can impair your ability to drive or operate machinery. Avoid these activities until you know how the medication affects you.
  • Monopril HCT can cause an electrolyte imbalance, which may lead to muscle cramps, weakness, or fatigue. Talk to your healthcare provider if you experience these symptoms.
  • Monopril HCT can cause a persistent cough in some people. If this happens, talk to your healthcare provider who may recommend an alternative medication.

Frequently Asked Questions (FAQ)

Can I take other medications with Monopril HCTZ?

Aluminum or magnesium-containing antacids and certain cholesterol-lowering drugs such as bile acid-binding resins can reduce the absorption of Monopril HCTZ. Therefore, it is recommended to take them at least 2 or 4-6 hours apart from this medication, respectively. You should consult your doctor or pharmacist before taking any new medication, including over-the-counter drugs.

How long does it take for Monopril HCTZ to start working?

It may take several weeks before you experience the full benefit of this medication.

What should I do if I miss a dose of Monopril HCTZ?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.


It's important to purchase Monopril HCTZ from verified Canadian pharmacy.

Additional information

Generic name:

Fosinopril Hctz




10/12.5mg, 20/12.5mg

Quantities Available: