Prescription Required
Formulation: Tablet
(Brand Option)
Select the prescribed dosage
Select the quantity to see the price.
Prescription Required
Formulation: Tablet
(Generic Alternative)
Select the prescribed dosage
Select the quantity to see the price.
* This price includes a dispensing fee, medical review fee, and packing fee.
Shipped and delivered directly to your doorstep
Pletal contains the active ingredient cilostazol. It is a prescription medication used to reduce the symptoms of intermittent claudication and help you walk farther with less leg discomfort.
Intermittent claudication is a symptom of peripheral artery disease. It develops when the arteries that carry blood to your legs become narrowed or blocked. As a result, your leg muscles may not receive enough oxygen-rich blood when you walk or exercise.
You may experience:
These symptoms may make it difficult to walk long distances or complete everyday activities.
Pletal belongs to a group of medications called phosphodiesterase III inhibitors. It works in two main ways.
First, it helps relax and widen the blood vessels. This allows more blood and oxygen to reach the muscles in your legs.
Second, it reduces the tendency of platelets to stick together. Platelets are small blood cells involved in blood clotting.
By improving circulation, Pletal may help you walk for a longer distance before pain or cramping begins. Clinical studies show that cilostazol can improve walking distance in people with intermittent claudication.
Pletal does not usually relieve leg pain immediately. It may take several weeks before you notice an improvement in your walking ability.
Some people may need up to 12 weeks of treatment to experience the full benefit. Your healthcare provider may assess whether the medication is helping by asking how far you can walk before symptoms begin.
Continue taking Pletal as prescribed, even if you do not notice an immediate improvement. Do not increase your dose to make it work faster.
Pletal can improve the symptoms of intermittent claudication, but it does not cure peripheral artery disease or remove existing blockages from your arteries.
It has not been proven to prevent every serious complication of peripheral artery disease, such as heart attack, stroke, limb procedures, or amputation. Its approved purpose is to reduce claudication symptoms and increase walking distance.
Pletal is usually most effective when combined with other treatments that support circulation and cardiovascular health. Your healthcare provider may recommend:
Walking exercise is especially important. Regular walking can gradually train your muscles to use oxygen more efficiently and may improve how far you can walk before discomfort begins.
Do not take Pletal if you have heart failure of any severity. Cilostazol carries a boxed warning because medications with the same phosphodiesterase III effect have been associated with reduced survival in some people with advanced heart failure.
Tell your healthcare provider if you have ever been diagnosed with heart failure or have symptoms such as shortness of breath, swelling in your legs or feet, rapid weight gain, or unusual fatigue.
Take Pletal only as directed by your healthcare provider. Contact them if your leg symptoms become worse, occur while you are resting, or if you develop sores on your feet or legs that do not heal. These may be signs that the blood flow to your legs has become more severely reduced.
Pletal is available as a tablet that you take by mouth. The usual adult dose is 100 mg twice a day, although your healthcare provider may prescribe a lower dose in some situations.
Take Pletal on an empty stomach. You should take each dose:
Taking Pletal with food can increase the amount of medication absorbed into your body. This may increase the risk of side effects, so it is important to follow the meal-timing instructions carefully.
Try to take your doses at approximately the same times every day. For example, you may take one dose before breakfast and the second dose before dinner. Swallow the tablet with water.
Your healthcare provider will choose the most appropriate dose based on:
The usual dose is 100 mg twice daily. However, your healthcare provider may reduce the dose to 50 mg twice daily if you take certain medications that increase the amount of cilostazol in your body.
Tell your healthcare provider about all medications and supplements
Before starting Pletal, give your healthcare provider and pharmacist a complete list of everything you take. This includes:
Some medications can interact with Pletal and increase the risk of side effects. These may include certain antibiotics, antifungal medications, stomach-acid medications, and drugs that affect blood clotting.
Do not start, stop, or change any medication without first speaking with your healthcare provider or pharmacist.
Take the missed dose when you remember, unless it is almost time for your next scheduled dose. If your next dose is approaching, skip the missed dose and continue with your regular schedule.
Do not take two doses at the same time or take extra tablets to make up for a missed dose.
Pletal does not provide immediate relief. You may begin to notice an improvement in your walking ability within 2 to 4 weeks. However, it may take up to 12 weeks to experience the full benefit.
Continue taking Pletal as prescribed, even if you do not notice an improvement right away. Your healthcare provider may review your symptoms after several weeks to determine whether the medication is helping.
Do not take more Pletal than prescribed or use it more often than directed. Taking extra medication will not improve your symptoms faster and may increase your risk of headache, dizziness, diarrhea, or a rapid heartbeat.
Do not stop taking Pletal without speaking with your healthcare provider. Your leg symptoms may return after treatment is stopped.
Contact your healthcare provider or pharmacist if you are unsure about your dose, meal timing, possible medication interactions, or how long you should continue treatment.
Pletal (Cilostazol) is available in the following forms and strengths:
Before taking Pletal, tell your healthcare provider about all your medical conditions, medications, supplements, and herbal products. Cilostazol can affect your heart rate, blood pressure, and blood clotting, so your healthcare provider needs a complete picture of your health before starting treatment.
Do not take Pletal if you have heart failure of any severity. Cilostazol affects an enzyme called phosphodiesterase III. Other medications that affect this enzyme have been associated with an increased risk of death in people with heart failure.
Tell your healthcare provider if you have heart failure or symptoms that may suggest a heart problem, such as:
Seek prompt medical attention if these symptoms develop while you are taking Pletal.
Tell your healthcare provider if you have kidney or liver disease. These organs help your body process and remove medications.
People with mild kidney impairment generally do not require a cilostazol dose adjustment. However, the medication has not been adequately studied in people receiving dialysis.
People with mild liver impairment generally do not require a dose adjustment. Cilostazol has not been sufficiently studied in people with moderate or severe liver impairment, so it may not be suitable for them.
Your healthcare provider will review the severity of your condition and determine whether Pletal is appropriate for you. Do not change your dose on your own.
Cilostazol can interact with several medications. Some interactions can increase the amount of cilostazol in your blood, which may raise your risk of headache, diarrhea, dizziness, palpitations, or other side effects.
Before starting Pletal, tell your healthcare provider and pharmacist about everything you take, including:
Certain medications can slow the breakdown of cilostazol. These include some antibiotics, antifungal medications, heart medications, and stomach-acid treatments. Examples include erythromycin, ketoconazole, itraconazole, diltiazem, fluconazole, and omeprazole.
When cilostazol is used with certain interacting medications, your healthcare provider may reduce the dose from 100 mg twice daily to 50 mg twice daily.
Cilostazol prevents platelets from sticking together as easily. Platelets are blood cells that help stop bleeding. This effect can increase your tendency to bruise or bleed.
The risk may be greater if you also take medications that affect blood clotting, such as:
Tell your healthcare provider if you have a bleeding disorder, an active stomach ulcer, recent surgery, or a history of unusual bleeding. Cilostazol should generally be avoided in people with active abnormal bleeding.
Contact your healthcare provider promptly if you notice:
Do not stop a prescribed blood thinner or antiplatelet medication without speaking with your healthcare provider.
Grapefruit may affect the way your body breaks down cilostazol and could increase the amount of medication in your bloodstream. This may increase the risk of side effects.
Ask your healthcare provider or pharmacist whether you should avoid grapefruit and grapefruit juice during treatment. Do not make major changes to your diet without discussing them with a healthcare professional.
Tell your healthcare provider if you are pregnant, think you may be pregnant, or are planning to become pregnant.
There is limited information about cilostazol use during human pregnancy. Animal studies found harmful effects at certain doses, but animal results do not always predict what will happen in humans.
Your healthcare provider will consider the potential benefits and possible risks before deciding whether you should use Pletal during pregnancy.
Tell your healthcare provider if you are breastfeeding or planning to breastfeed. It is not known whether cilostazol passes into human breast milk.
Because the medication could potentially cause serious effects in a nursing baby, your healthcare provider may recommend choosing a different medication or avoiding breastfeeding during treatment. The decision will depend on your health needs and the importance of the medication.
Pletal may cause dizziness, lightheadedness, weakness, or low blood pressure. These effects may be more noticeable when you first start treatment or when your dose changes.
To reduce dizziness:
Do not drive, operate machinery, or perform activities that require full alertness until you know how Pletal affects you.
Headache is one of the most commonly reported side effects of cilostazol. The medication can also cause a fast heartbeat, pounding heartbeat, or palpitations.
Cilostazol may increase heart rate by approximately 5 to 7 beats per minute in some people. People with a history of heart rhythm problems, chest pain, or coronary artery disease may require closer monitoring.
Contact your healthcare provider immediately if you develop:
Take Pletal exactly as prescribed. Do not increase your dose, take it more often, or combine it with another medication without checking with your healthcare provider or pharmacist.
Regular medical follow-up allows your healthcare provider to check whether Pletal is improving your walking ability and whether you are experiencing any harmful effects.
Yes. Pletal may be used with other treatments for peripheral vascular disease, also called peripheral artery disease. Your treatment plan may include antiplatelet medications, cholesterol-lowering medications, blood pressure treatment, diabetes management, and a regular walking program. Some combinations can increase the risk of bleeding or other side effects. Tell your healthcare provider and pharmacist about all prescription medications, over-the-counter products, vitamins, and supplements you take. Do not start or stop another medication without medical advice.
There is limited information about the safety of Pletal during pregnancy. Tell your healthcare provider if you are pregnant, planning to become pregnant, or think you may be pregnant. Pletal should only be used when your healthcare provider determines that the expected benefits outweigh the possible risks. It is not known whether Pletal passes into human breast milk. Speak with your healthcare provider if you are breastfeeding or planning to breastfeed. They may recommend a different medication or advise you not to breastfeed during treatment.
Weight gain is not a common side effect of Pletal. However, sudden or unexplained weight gain may be caused by fluid buildup and should not be ignored, especially if it occurs with swelling in the feet or legs, shortness of breath, or unusual tiredness. Contact your healthcare provider promptly if you notice these symptoms. Pletal must not be used by people with heart failure.
Pletal does not usually improve symptoms immediately. You may begin to notice that you can walk farther with less leg pain after 2 to 4 weeks of treatment. It may take up to 12 weeks to experience the full benefit. Continue taking Pletal as prescribed, and speak with your healthcare provider if your symptoms do not improve after several weeks.
| Generic name: | Cilostazol |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 100mg |
| Quantities Available: | 60, 120 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Pletal (cilostazol) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is standard practice for prescription medications to ensure effective management of chronic conditions without the need for frequent refills.
Here’s what you need to know:
Dosage and Quantity: Pletal is commonly prescribed in dosages of 100 mg, taken twice daily. For a 90-day supply, this means you would order 180 tablets (90 days x 2 tablets per day).
Yes, we sell cilostazol on our website, and you can enjoy low prices. To purchase cilostazol, you will need a valid prescription from your healthcare provider. We require this to dispense the medication. You can conveniently submit your prescription by mail, fax, or upload it through your online account to facilitate the ordering process.
Yes, we ship Pletal (cilostazol) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Pletal (Cilostazol). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Pletal (Cilostazol).
REVIEWS