Indications
Pletal (active ingredient: cilostazol) is a prescription medication indicated for:
- Intermittent Claudication: Pletal is used to improve the symptoms of intermittent claudication, including pain, cramping, numbness, or weakness in the legs, which may occur during physical activity due to reduced blood flow.
Pletal belongs to a class of drugs known as phosphodiesterase inhibitors, which work by widening blood vessels and increasing blood flow to the legs. This helps to reduce the symptoms associated with intermittent claudication and improve walking distance in patients with this condition.
Uses and Dosage
Pletal comes in the form of Pletal to take this medication by mouth without food as directed by your doctor, usually twice daily, at least 30 minutes before or 2 hours after breakfast and dinner. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Typical dosing for cilostazol (the active ingredient in Pletal) is 100 mg taken orally twice a day on an empty stomach, at least 30 minutes before or 2 hours after breakfast and dinner. However, follow the specific dosing instructions provided by your doctor and inform them of any other medications or supplements you may be taking.
Side Effects
Common Side Effects of Pletal (Cilostazol):
Serious Side Effects of Pletal (Cilostazol):
- A light-headed feeling
- Chest pain
- Chills
- Easy bruising
- Fever
- Faint
- Mouth sores
- Pounding heartbeats or fluttering in your chest
- Purple or red spots under your skin.
- Sore throat
- Unusual bleeding
Form and Strength
Pletal (Cilostazol) is available in the following forms and strengths:
Pletal: Tablet
- 100mg
Cilostazol: Tablet
- 100mg
Caution
- Cilostazol should be used with caution in patients with kidney or liver disease, as it may require dose adjustments or may not be suitable for some patients.
- Cilostazol may interact with certain medications, such as blood thinners and some antidepressants. Inform your doctor of all medications you are taking before starting cilostazol. Additionally, grapefruit juice should be avoided while taking cilostazol.
- Limited information is available on the safety of cilostazol during pregnancy or breastfeeding, so it is not recommended for use in these populations.
- Cilostazol should be used with caution in patients with kidney or liver disease, as it may require dose adjustments or may not be suitable for some patients.
- Cilostazol may interact with certain medications, such as blood thinners and some antidepressants. It is important to inform your doctor of all medications you are taking before starting cilostazol.
- Cilostazol may increase the risk of bleeding, especially in patients who are also taking blood thinners or have a history of bleeding disorders. It is important to speak with your doctor if you have any concerns about this risk.
- Cilostazol may have side effects such as dizziness, headache, and low blood pressure. Patients should not drive or operate heavy machinery until they know how cilostazol affects them.
Frequently Asked Questions (FAQ)
Can cilostazol be used in combination with other medications for PVD?
Yes, cilostazol can be used in combination with other medications for PVD, such as antiplatelet therapy and lipid-lowering therapy, to provide maximum benefit to patients. However, speak with your doctor to determine the best treatment plan for you.
Is cilostazol safe during pregnancy or breastfeeding?
The safety of cilostazol during pregnancy or breastfeeding is not well-established, so it should be avoided unless the potential benefits outweigh the risks. Pregnant or breastfeeding individuals should talk to their doctor before taking cilostazol.
Can cilostazol cause weight gain?
Weight gain is not a common side effect of cilostazol, but it may occur in some patients. It is important to speak with your doctor if you experience any unusual changes in weight or appetite.
How long does it take for cilostazol to start working?
It may take several weeks for cilostazol to start working and for patients to notice an improvement in their symptoms.
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