Skip to main content

Lamictal XR (Lamotrigine Xr) Shopper Approved

Prescription Prescription Required FormationFormulation: Extended Release Tablet

Lamictal XR

We don't sell this brand-version medication.

  *  
Prescription Prescription Required FormationFormulation: Extended Release Tablet

Lamotrigine Xr

(Generic Alternative)

Select the prescribed dosage

Select the quantity to see the price.

  *  
delivery

* This price includes a dispensing fee, medical review fee, and packing fee.

delivery

Shipped and delivered directly to your doorstep

Lamictal XR (active ingredient: lamotrigine) is a prescription medication used to treat certain types of seizure disorders and to help manage bipolar I disorder. It belongs to a class of medications known as anticonvulsants or antiepileptic drugs.

Lamictal XR is an extended-release (XR) formulation, which means the medication is released gradually throughout the day, helping to maintain more consistent drug levels in the body and allowing for convenient once-daily dosing.

What Is Lamictal XR Used For?

Epilepsy

Lamictal XR is used as an adjunctive (add-on) treatment for certain types of seizures in patients 13 years of age and older.

It may be prescribed to help control:

  • Partial-onset seizures
  • Primary generalized tonic-clonic seizures
  • Generalized seizures associated with Lennox-Gastaut syndrome

Epilepsy is a neurological condition characterized by recurrent seizures caused by abnormal electrical activity in the brain.

By helping stabilize electrical activity, Lamictal XR may:

  • Reduce seizure frequency
  • Decrease seizure severity
  • Improve seizure control
  • Support overall quality of life

Bipolar I Disorder

Lamictal XR is also indicated for the maintenance treatment of bipolar I disorder.

Bipolar I disorder is a mental health condition characterized by significant shifts in mood, energy levels, and activity levels, including episodes of:

  • Depression
  • Mania
  • Hypomania
  • Mixed mood episodes

Lamictal XR is used to help delay the recurrence of mood episodes in patients whose acute symptoms have already been stabilized with standard treatment.

Regular use may help:

  • Maintain mood stability
  • Reduce the frequency of mood episodes
  • Support long-term management of bipolar disorder

Lamictal XR is not typically used as the sole treatment for acute manic episodes.

How Does Lamictal XR Work?

Although the exact mechanism is not fully understood, lamotrigine is believed to work by helping stabilize nerve cell activity in the brain.

Stabilizing Neuronal Membranes

Lamotrigine helps regulate the electrical activity of neurons (nerve cells) by blocking certain sodium channels involved in the transmission of nerve signals.

This action helps:

  • Reduce excessive electrical activity in the brain
  • Prevent abnormal nerve firing
  • Improve seizure control

Reducing Excitatory Neurotransmitter Release

Lamotrigine also helps decrease the release of excitatory neurotransmitters, particularly glutamate.

Excessive glutamate activity can contribute to:

  • Seizure activity
  • Mood instability
  • Abnormal brain signaling

By reducing the release of these neurotransmitters, Lamictal XR helps promote more stable brain activity.

Supporting Mood Stability

In bipolar disorder, lamotrigine’s effects on neurotransmitter signaling and neuronal stability are believed to contribute to its mood-stabilizing properties.

These actions may help:

  • Reduce the risk of depressive episodes
  • Delay the recurrence of mood episodes
  • Support long-term emotional stability

Benefits of Lamictal XR

When used as prescribed, Lamictal XR may help:

  • Reduce seizure frequency and severity
  • Improve seizure control
  • Support long-term epilepsy management
  • Delay the recurrence of mood episodes in bipolar I disorder
  • Promote mood stability
  • Provide convenient once-daily dosing through its extended-release formulation

Because treatment is individualized, your healthcare provider will determine the dose and treatment plan that best meets your needs.

Lamictal XR is available as an oral tablet and is typically taken once daily, with or without food, as directed by your healthcare provider.

Swallow the tablet whole with water. Do not crush, chew, or split the tablet, as this can interfere with the extended-release mechanism and cause the medication to be released too quickly, which may increase the risk of side effects.

For best results, take Lamictal XR at approximately the same time each day to help maintain consistent medication levels in your body.

Recommended Dosages

The appropriate dosage of Lamictal XR varies depending on:

  • The condition being treated
  • Your age
  • Other medications you are taking
  • Your response to treatment

Because lamotrigine must be introduced gradually, your healthcare provider will slowly increase the dose over several weeks to help reduce the risk of serious side effects.

Patients Not Taking Enzyme-Inducing Antiepileptic Drugs

For patients who are not taking enzyme-inducing antiepileptic drugs (AEDs), the typical dosing schedule is:

  • 25 mg once daily for 2 weeks
  • Then 50 mg once daily for 2 weeks
  • Followed by a maintenance dose of 200 mg once daily

Patients Taking Enzyme-Inducing Antiepileptic Drugs (Without Valproic Acid)

For patients taking enzyme-inducing AEDs, but not valproic acid, the typical dosing schedule is:

  • 50 mg once daily for 2 weeks
  • Then 100 mg daily (usually divided into two doses) for 2 weeks
  • Followed by a maintenance dose of approximately 300 mg once daily

Patients Taking Valproic Acid

Valproic acid can significantly affect how lamotrigine is processed by the body, requiring a slower dosing schedule.

Typical dosing may include:

  • 25 mg every other day for 2 weeks
  • Then 25 mg once daily for 2 weeks
  • Followed by a maintenance dose of approximately 200 to 400 mg daily, depending on individual treatment needs

Your healthcare provider will determine the most appropriate dose based on your specific circumstances.

Switching From Immediate-Release Lamotrigine

If you are switching from an immediate-release form of lamotrigine to Lamictal XR, your healthcare provider will typically prescribe a dose that is similar to your current daily dose and make adjustments as needed.

Always follow your healthcare provider’s instructions when transitioning between formulations.

Important Dosing Tips

  • Take Lamictal XR exactly as prescribed.
  • Do not skip doses or take extra doses.
  • Take the medication at the same time each day.
  • Do not crush, chew, or split the tablets.
  • Follow the dose-escalation schedule carefully.
  • It may take several weeks or even months to reach the optimal dose and experience the full benefits of treatment.

Do Not Stop Lamictal XR Suddenly

Do not stop taking Lamictal XR without first consulting your healthcare provider.

Suddenly discontinuing the medication may:

  • Increase the risk of seizures
  • Worsen seizure control
  • Increase the risk of mood episode recurrence in bipolar disorder
  • Cause other complications related to your condition

If treatment needs to be stopped, your healthcare provider will usually recommend gradually reducing the dose over time.

Additionally, if you have stopped taking Lamictal XR for any reason, do not restart the medication on your own. Contact your healthcare provider, as you may need to restart treatment using a gradual dose-titration schedule.

Common Side Effects of Lamictal XR (Lamotrigine Xr):

  • Anxiety
  • Back pain
  • Constipation
  • Cough
  • Diarrhea
  • Dizziness
  • Double vision
  • Dry mouth
  • Flu-like symptoms
  • Indigestion
  • Nausea
  • Tremor
  • Trouble sleeping
  • Trouble with balance and coordination
  • Vomiting
  • Worsening seizure

Serious Side Effects of Lamictal XR (Lamotrigine XR):

  • Allergic reactions: skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Blistering
  • Change in vision
  • Dark yellow or brown urine
  • Including inside the mouth
  • Light-colored stool
  • Loss of appetite
  • Peeling or loosening of the skin
  • Redness
  • Right upper belly pain
  • Swollen lymph nodes
  • Thoughts of suicide or self-harm, worsening mood, or feelings of depression
  • Trouble breathing
  • Unusual bruising or bleeding
  • Unusual weakness or fatigue
  • Yellowing skin or eyes

Lamictal XR (Lamotrigine Xr) is available in the following forms and strength:

Lamotrigine Xr: Extended-Release Tablet

  • 50 mg
  • 100 mg
  • 200 mg

Before taking Lamictal XR, discuss your medical history, current medications, and any health concerns with your healthcare provider. Careful dosing and monitoring are important to help reduce the risk of serious side effects and ensure safe treatment.

Risk of Medication Errors

Lamictal XR has a name that may be confused with other medications that have similar-sounding names. To help prevent medication errors, always verify that you have received the correct medication and strength before taking it.

If you are unsure about your prescription, consult your pharmacist or healthcare provider.

Serious Skin Reactions

One of the most important warnings associated with Lamictal XR is the risk of developing a serious skin rash, which can occasionally be severe or life-threatening.

The risk may be higher if:

  • The starting dose is too high
  • The dose is increased too quickly
  • Lamotrigine is taken with certain medications, such as valproic acid

Contact your healthcare provider immediately if you develop:

  • A rash
  • Skin blistering
  • Peeling skin
  • Sores in the mouth
  • Fever or flu-like symptoms accompanying a rash

Never ignore a new rash while taking Lamictal XR.

Kidney Problems

Patients with significant kidney impairment may require special consideration when taking Lamictal XR.

Your healthcare provider may recommend:

  • Dose adjustments
  • More frequent monitoring
  • Additional follow-up visits

Be sure to inform your healthcare provider if you have a history of kidney disease or reduced kidney function.

Use in Children

The safety and effectiveness of Lamictal XR have not been fully established in children younger than 13 years of age.

Use in pediatric patients should only occur under the guidance of a qualified healthcare provider.

Common Side Effects

Some patients may experience side effects while taking Lamictal XR, including:

  • Dizziness
  • Headache
  • Nausea
  • Drowsiness
  • Skin rash

Many side effects improve as the body adjusts to treatment, but persistent or bothersome symptoms should be discussed with your healthcare provider.

Suicidal Thoughts and Behavioral Changes

Antiepileptic medications, including Lamictal XR, have been associated with an increased risk of suicidal thoughts or behaviors in some individuals.

Patients, family members, and caregivers should watch for:

  • New or worsening depression
  • Mood changes
  • Anxiety
  • Agitation
  • Suicidal thoughts or actions
  • Unusual behavioral changes

Contact your healthcare provider immediately if any of these symptoms occur.

Heart Rhythm Problems

Lamictal XR may increase the risk of heart rhythm abnormalities in certain patients, particularly those with underlying heart conditions or seizure disorders.

Inform your healthcare provider if you have:

  • Heart disease
  • Abnormal heart rhythms
  • A history of fainting
  • Other cardiovascular conditions

Seek medical attention if you experience symptoms such as:

  • Rapid heartbeat
  • Irregular heartbeat
  • Dizziness
  • Fainting

Do Not Stop Treatment Abruptly

Do not stop taking Lamictal XR suddenly unless directed by your healthcare provider.

Abrupt discontinuation may:

  • Increase the risk of seizures
  • Trigger withdrawal seizures
  • Worsen seizure control
  • Increase the risk of mood episode recurrence in bipolar disorder

If treatment needs to be stopped, your healthcare provider will usually recommend gradually reducing the dose.

Drug Interactions and Dose Adjustments

Certain medications can affect how Lamictal XR is processed by the body and may require dosage adjustments.

Examples include medications that affect liver enzymes, such as:

  • Valproic acid
  • Carbamazepine
  • Phenytoin
  • Phenobarbital
  • Primidone

Your healthcare provider will determine the appropriate dose based on your complete medication profile.

Hormonal Contraceptives

Lamictal XR may interact with hormonal contraceptives, including birth control pills.

These interactions may:

  • Affect lamotrigine blood levels
  • Reduce the effectiveness of hormonal contraceptives
  • Alter seizure or mood control

Women using hormonal contraception should discuss birth control options and monitoring plans with their healthcare provider. Additional or alternative contraceptive methods may be recommended.

Dizziness and Drowsiness

Lamictal XR may cause:

  • Dizziness
  • Drowsiness
  • Blurred vision
  • Coordination problems

Until you know how the medication affects you, avoid:

  • Driving
  • Operating machinery
  • Activities requiring mental alertness

Medication and Supplement Interactions

Lamictal XR may interact with prescription medications, over-the-counter products, vitamins, herbal supplements, and other health products.

Before starting treatment, provide your healthcare provider with a complete list of everything you take, including:

  • Prescription medications
  • Nonprescription medications
  • Vitamins
  • Herbal supplements
  • Natural health products

This helps reduce the risk of potentially harmful drug interactions.

When to Contact Your Healthcare Provider

Contact your healthcare provider immediately if you experience:

  • A skin rash
  • Signs of an allergic reaction
  • Suicidal thoughts or mood changes
  • Irregular heartbeat or fainting
  • Severe dizziness
  • Worsening seizures
  • Any new or unusual symptoms

Regular follow-up appointments and careful dose adjustments can help ensure that Lamictal XR remains a safe and effective treatment for epilepsy or bipolar disorder.

Is Lamictal XR Safe to Take During Pregnancy?

The safety of Lamictal XR during pregnancy has not been fully established. If you are pregnant, planning to become pregnant, or think you may be pregnant, discuss the potential risks and benefits of treatment with your healthcare provider. For some individuals, continuing treatment may be important to maintain seizure control or mood stability. Your healthcare provider can help determine the most appropriate treatment plan based on your individual circumstances. Do not start, stop, or change your dose of Lamictal XR during pregnancy without medical advice.

Is It Safe to Stop Taking Lamictal XR Abruptly?

No. You should not stop taking Lamictal XR suddenly unless specifically instructed by your healthcare provider. Abruptly discontinuing the medication may increase the risk of seizures, trigger withdrawal seizures, worsen seizure control, and increase the risk of recurring mood episodes in patients with bipolar disorder. If Lamictal XR needs to be discontinued, your healthcare provider will typically recommend gradually reducing the dose over time to help minimize potential complications and ensure a safer transition off the medication.

Can Lamictal XR Cause Weight Gain?

Weight gain is not considered a common side effect of Lamictal XR. Most people taking lamotrigine do not experience significant weight changes related to the medication. However, individual responses can vary, and factors such as diet, activity level, underlying medical conditions, and other medications may affect body weight. If you notice unusual weight gain, weight loss, or other concerning symptoms while taking Lamictal XR, speak with your healthcare provider.

What Should I Do If I Miss a Dose of Lamictal XR?

If you miss a dose of Lamictal XR, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at the same time or take extra medication to make up for a missed dose, as this may increase the risk of side effects. If you miss multiple doses or are unsure how to safely restart your medication, contact your healthcare provider for guidance. In some cases, a gradual dose adjustment may be necessary before resuming treatment to help reduce the risk of serious side effects.

REVIEWS

Additional Information Book
Generic name:

Lamotrigine Xr

Formulation:

Extended Release Tablet

Strength(s):

50mg, 100mg, 200mg

Quantities Available:

90, 100

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Lamictal XR can I order at once from a Canadian pharmacy?

When ordering Lamictal XR (lamotrigine) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Lamictal XR is commonly prescribed in various dosages, such as 50 mg, 100 mg, and 200 mg, taken once daily. For a 90-day supply, you would order 90 tablets (90 days x 1 tablet per day).

Do you sell lamotrigine?

Yes, we sell lamotrigine. You can enjoy low prices when you order from us. To dispense the medication, you will need a valid prescription from your healthcare provider. We require this to ensure your safety and proper medication management. You can mail, fax, or upload your prescription through your online account.

Do you offer shipping of Lamictal XR (lamotrigine xr) to the United States?

Yes, we ship Lamictal XR (lamotrigine xr) to both the United States and Puerto Rico.

Discover Our Users' Stories!

Watch how Online Pharmacies Canada is helping customers save money on their medications.

Online Pharmacies Canada Customer Testimonial #4
Online Pharmacies Canada Customer Testimonial #1
Online Pharmacies Canada - Customer Testimonial #2

Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Lamictal XR (Lamotrigine Xr). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Lamictal XR (Lamotrigine Xr).