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Kombiglyze XR (Metformin/Saxagliptin) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet

Kombiglyze XR

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Prescription Prescription Required FormationFormulation: Tablet

Metformin/Saxagliptin

We don't sell this generic-version medication.

Select the quantity to see the price.

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Kombiglyze XR (active ingredients: metformin and saxagliptin) is a prescription medication indicated for:

  • Type 2 Diabetes Mellitus: Kombiglyze XR is used to improve glycemic control in adults with type 2 diabetes mellitus as an adjunct to diet and exercise.

Kombiglyze XR belongs to a class of drugs known as combination antidiabetics. Saxagliptin is a DPP-4 inhibitor that helps regulate blood sugar levels by increasing incretin hormones, while metformin is a biguanide that decreases glucose production in the liver and improves insulin sensitivity.

Kombiglyze XR comes in the form of a tablet to take by mouth, once a day, usually with the evening meal. Swallow the tablet whole without crushing or chewing it because breaking the tablet can cause an increase in the risk of side effects. Drinking plenty of fluids while taking the medication unless otherwise directed can help in its effectiveness.

The dosage of Kombiglyze XR is dependent on your medical condition, response to treatment, and other medications you may be taking. Your doctor may direct you to start at a low dose and gradually increase the dosage to reduce the risk of side effects.

To get the most benefit from Kombiglyze XR, take it regularly at the same time each day. Follow the medication plan, meal plan, and exercise program recommended by your doctor carefully. Remember to tell your doctor and pharmacist about all the products you use, including prescription drugs, nonprescription drugs, and herbal products, to avoid any potential interactions.

Overall, follow the instructions provided by your healthcare provider while taking Kombiglyze XR to ensure its effectiveness and reduce the risk of side effects.

Common Side Effects of Kombiglyze XR (Metformin/Saxagliptin):

Serious Side Effects of Kombiglyze XR (Metformin/Saxagliptin):

  • Blisters
  • Breakdown of the outer layer of skin
  • Difficulty breathing
  • Dizziness
  • Fast heartbeats
  • Feeling cold
  • Hives
  • Irregular heart rate
  • Itching
  • Lightheadedness
  • Loss of appetite
  • Nausea
  • Pain or burning when you urinate
  • Peeling skin
  • Rapid weight gain
  • Severe or ongoing pain in your joints
  • Severe pain in your upper stomach spreading to your back
  • Shortness of breath
  • Stomach pain
  • Swelling in your legs or feet
  • Swelling of your face lips tongue or throat
  • Tiredness
  • Unusual muscle pain
  • Vomiting
  • Weakness

Kombiglyze XR (Metformin/Saxagliptin) is available in the following forms and strength:

Kombiglyze XR: Tablet

  • 5/500mg
  • 5/1000mg
  • 2.5/1000mg

  • Pancreatitis: Kombiglyze XR may increase the risk of developing pancreatitis, an inflammation of the pancreas. Patients should seek medical attention immediately if they experience severe and persistent abdominal pain.
  • Heart Failure: Kombiglyze XR has been associated with an increased risk of heart failure, particularly in patients with a history of heart or kidney problems.
  • Lactic Acidosis: Kombiglyze XR can increase the risk of developing a serious condition called lactic acidosis, which can cause symptoms such as weakness, muscle pain, and breathing difficulties. Patients should seek medical attention immediately if they experience these symptoms.
  • Kidney Problems: Kombiglyze XR can cause or worsen kidney problems, so patients with kidney disease need to be monitored closely while taking this medication.
  • Hypoglycemia: Kombiglyze XR can cause low blood sugar levels, which can lead to symptoms such as shaking, sweating, and confusion. Patients should be aware of the signs of hypoglycemia and take steps to prevent it.
  • Stomach Problems: Kombiglyze XR can cause stomach problems such as diarrhea and nausea, especially during the first few weeks of treatment.
  • Liver Problems: Kombiglyze XR can cause or worsen liver problems, so patients with liver disease need to be monitored closely while taking this medication.
  • Vitamin B12 Deficiency: Long-term use of Kombiglyze XR can lead to vitamin B12 deficiency, especially in patients who already have low levels of this vitamin.
  • Surgery: Patients taking Kombiglyze XR should inform their healthcare provider or surgeon before undergoing any surgery, as the medication may need to be temporarily discontinued.
  • Allergic Reactions: Some patients may have an allergic reaction to Kombiglyze XR, which can cause symptoms such as rash, hives, and difficulty breathing.

Can Kombiglyze XR be used to treat type 1 diabetes?

No, Kombiglyze XR is only approved for use in adults with type 2 diabetes.

Can Kombiglyze XR be used by people with kidney problems?

Kombiglyze XR should be used with caution in people with kidney problems. The dosage may need to be adjusted to prevent any potential side effects.

How long does it take for Kombiglyze XR to start working?

Kombiglyze XR can start working within hours of taking the first dose, but it may take several weeks for the full effects to be seen. Patients should continue taking Kombiglyze XR as directed by their healthcare provider.

Can Kombiglyze XR be used by people with liver problems?

Kombiglyze XR should be used with caution in people with liver problems. The dosage may need to be adjusted to prevent any potential side effects.

REVIEWS

Additional Information Book
Generic name:

Metformin/Saxagliptin

Formulation:

Tablet

Strength(s):

2.5/1000mg, 5/500mg, 5/1000mg

Quantities Available:

28, 56, 84, 112

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How to Order

How much Kombiglyze XR can I order at once from a Canadian pharmacy?

When ordering Kombiglyze XR (metformin/saxagliptin) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Kombiglyze XR is commonly prescribed in dosages of 2.5/1000 mg, 5/500 mg, or 5/1000 mg, taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).

Do you sell metformin/saxagliptin?

No, we do not sell metformin/saxagliptin directly on our website. However, you can still enjoy low prices on Kombiglyze XR, which contains metformin/saxagliptin as active ingredients. To purchase Kombiglyze XR, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You can submit your prescription by mailing it to us, faxing it, or uploading it through your online account.

Do you offer shipping of Kombiglyze XR (metformin/saxagliptin) to the United States?

Yes, we ship Kombiglyze XR (metformin/saxagliptin) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Kombiglyze XR (Metformin/Saxagliptin). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Kombiglyze XR (Metformin/Saxagliptin).