Indocin (Indomethacin)

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Indocin Brand

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Indomethacin (Generic alternate to Indocin) Generic
Dosage Quantity & Price
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Indocin, known by its generic name indomethacin oral medication, is indicated to relieve pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis. Indomethacin belongs to the class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs). It works by reducing the production of certain chemicals in the body that cause inflammation, pain, and fever.

Indomethacin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, and gouty arthritis. It is also used to treat ankylosing spondylitis, which is a type of arthritis that affects the spine. It can be used to relieve pain and other related symptoms caused by mild to moderate acute pain.

Uses and Dosage

To take Indocin capsules, follow the instructions given by your doctor. Typically, you will take them two to three times per day with a full glass of water (8 ounces or 240 milliliters). After taking the capsules, do not lie down for at least 10 minutes. If you experience stomach upset, take the capsules with food, milk, or an antacid. It is important to communicate with your healthcare provider about any questions or concerns you have while taking Indocin.

The recommended dosage of Indocin can vary depending on individual factors, such as the nature and severity of the condition being treated. However, in general, the recommended adult dosage is 25 mg taken two to three times per day, with the option for the doctor to increase the dose by 25 or 50 mg per day as needed. The maximum recommended daily dose for extended-release capsules is 150 mg.

Side Effects

Common Side Effects of Indocin (Indomethacin):

Indomethacin Allergic Reaction

  • Burning eyes
  • Difficult breathing swelling in your face or throat)
  • Hives
  • Red or purple skin rash with blistering and peeling)
  • Skin pain and rash
  • Sore throat
  • Itching

Serious Side Effects of Indocin (Indomethacin)

  • Bloody or tarry stools
  • Cold hands and feet
  • Coughing up blood or vomit that looks like coffee grounds
  • Dark urine
  • Diarrhea
  • Flu-like symptoms
  • Lightheadedness
  • Little or no urination
  • Pale skin
  • Rapid weight gain
  • Shortness of breath
  • Swelling in your feet or ankles
  • Swelling
  • Unusual tiredness
  • Upper stomach pain
  • Vision changes
  • Yellowing of the skin or eyes (jaundice)

Form and Strength

Indocin (Indomethacin) is available in the following forms and strengths:

Indomethacin: Capsule

  • 25 mg
  • 50 mg


  • Tell your doctor and pharmacist if you are allergic to indomethacin, aspirin, or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), any other medications, or any of the inactive ingredients.
  • Inform your doctor if you have a history of asthma, particularly if you frequently experience a stuffy or runny nose or have nasal polyps (swelling of the lining of the nose).
  • Indocin can worsen symptoms of depression or other psychiatric disturbances, epilepsy, and Parkinsonism, and must be used with significant caution in patients with these conditions.
  • Discourse to your doctor about the risks and benefits of taking indomethacin if you are 65 years of age or older. Older adults usually should not take indomethacin because it is not as safe as other medications that can be used to treat the same condition.
  • Indocin may cause drowsiness and headache, hence, patients should be cautioned about engaging in activities requiring mental alertness and motor coordination, such as driving a car.
  • Avoid taking alcohol while using indomethacin, as alcohol can make the side effects of indomethacin worse.
  • Do not take indomethacin around or after 20 weeks of pregnancy, unless directed to do so by your doctor. Indomethacin can harm the fetus and cause problems with delivery if taken later during pregnancy.

Frequently Asked Questions (FAQ)

Can I take Indomethacin with other medications?

First tell your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid potential drug interactions.

Is Indomethacin safe during pregnancy?

Indomethacin may not be safe during pregnancy, especially in the third trimester, as it may harm the fetus. Therefore, consult with your healthcare provider before taking Indomethacin if you are pregnant or planning to become pregnant.

Can Indomethacin be addictive?

No, Indomethacin is not addictive and does not have any abuse potential.

How long does it take for Indomethacin to work?

Indomethacin may start to relieve pain and swelling within a few hours, but it may take several weeks to see the full effects.

What should I do if I miss a dose of Indomethacin?

If you miss a dose of Indomethacin, take it as soon as possible, unless it is close to the time for your next dose. In that case, skip the missed dose and resume your regular dosing schedule.


It's important to purchase Indocin from verified Canadian pharmacy.

Additional information

Generic name:





25mg, 50mg

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