Gynest Vaginal Cream (Estriol)

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Gynest Vaginal Cream Brand
Dosage Quantity & Price
Estriol (Generic alternate to Gynest Vaginal Cream) Generic
Dosage Quantity & Price
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Gynest Vaginal Cream is a type of intravaginal cream used to treat vaginal dryness, itching, and irritation associated with menopause. It is a hormone replacement therapy (HRT) preparation that is given as a supplement to replace the falling hormone levels in the body. Gynest cream is only available on prescription.

Gynest Vaginal Cream is also known as Estriol Cream and contains 0.01% w/w of oestrogen. It works by supplementing the vaginal tissues with estriol, a form of estrogen, to improve vaginal atrophy symptoms related to menopause, such as vaginal dryness, itching, pain during intercourse, and urinary problems.

The cream is applied directly to the vaginal area and is absorbed into the local tissues to increase blood flow and restore vaginal tissue health.

Use and Dosage

Gynest Cream is to be applied into the vagina, using an applicator. Use Gynest cream for at least three months, after which you should see your doctor to determine if continued treatment is necessary.

To use Gynest vaginal cream, follow these steps,

  1. Remove the cap from the tube and invent it. Use the sharp point to open the point.
  2. Pull the plunger up you the ring. Now, attach it to the opened tube.
  3. Squeeze the tube slowly to fill the applicator to the ring-mark (where the applicator stops).
  4. Remove the tube.
  5. Lie down and insert the applicator deep into the vagina.
  6. Slowly pull the plunger all the way in until the applicator is empty.
  7. Pull the plunger out of the parrel beyond the point of resistance and wash both parts in warm, soapy water. Do not use any detergents. Do not put the applicator in hot and boiling water.
  8. Risen well and dry afterwards

Follow the instructions provided by your doctor and the product label carefully to ensure safe and effective use.

Side Effects

Common Side Effects of Gynest Vaginal Cream (Estriol):

  • Breast pain or tenderness
  • Headaches
  • Itching
  • Vaginal bleeding
  • Vaginal discharge

Forms and Strength

Gynest Vaginal Cream (Estriol) is available in the following forms and strength:

Gynest Vaginal Cream: Cream 

  • 0.01%

Estriol: Cream

  • 0.01%


  • Gynest Vaginal Cream should not be used by women who are pregnant or breastfeeding.
  • Gynest Vaginal Cream should not be used if you have a history of breast cancer, endometrial cancer, or liver disease.
  • Estriol may increase the risk of blood clots, strokes, heart attacks, and dementia in some women.
  • Estriol may increase the risk of certain types of cancer, such as endometrial cancer, especially if used for a long time.
  • Estriol may cause some side effects, such as vaginal discharge or irritation, breast tenderness, headaches, or nausea.
  • Estriol may interact with certain medications, supplements, or foods, inform your doctor and pharmacist about all the drugs you are taking.
  • Estriol uses the lowest effective dose for the shortest duration possible to minimize the risks of side effects and adverse outcomes.
  • Regular monitoring may be necessary to check for any potential side effects or changes in your health status.
  • In rare cases, allergic reactions may occur, which can cause itching, swelling, difficulty breathing, or other symptoms. Seek medical attention immediately if you experience any of these symptoms.

Frequently Asked Questions (FAQ)

Can Gynest Vaginal Cream be used by women who have had a hysterectomy?

Yes, Gynest Vaginal Cream can be used by women who have had a hysterectomy because they no longer have a uterus.

How often should Gynest Vaginal Cream be used?

The frequency of use will depend on the individual and the severity of symptoms. Your doctor or healthcare provider will provide specific instructions for use.

What should I do if I miss a dose of Gynest Vaginal Cream?

If you miss a dose of Gynest Vaginal Cream, apply it as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule.

Can Gynest Vaginal Cream be used together with other medications?

Gynest Vaginal Cream may interact with certain medications or supplements, inform your doctor or pharmacist about all the drugs you are taking.

Is a prescription needed for Gynest Vaginal Cream?

Yes, Gynest Vaginal Cream requires a prescription from a doctor or healthcare provider.


It's important to purchase Gynest Vaginal Cream from verified Canadian pharmacy.

Additional information

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