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Formulation: Tablet
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Prescription Required
Formulation: Tablet
Select the quantity to see the price.
* This price includes a dispensing fee, medical review fee, and packing fee.
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Activella contains two hormones: estradiol and norethindrone acetate. It is a prescription hormone therapy used in postmenopausal women to relieve certain menopause symptoms and help prevent osteoporosis.
Estradiol replaces some of the estrogen that the body produces less of after menopause. Norethindrone acetate is a progestin that helps protect the lining of the uterus from the effects of estrogen.
Activella is used to treat moderate to severe vasomotor symptoms associated with menopause. These symptoms may include:
These symptoms occur because estrogen levels decline during menopause. Activella helps restore hormone levels and may reduce how often these symptoms occur and how severe they feel.
Activella may also be used to help prevent osteoporosis after menopause. Osteoporosis causes bones to become weak and more likely to break.
Lower estrogen levels after menopause can increase bone loss. By replacing estrogen, Activella can help slow bone loss and support bone strength.
When Activella is used only to prevent osteoporosis, it is generally considered for women who have a significant risk of fractures and cannot use, or have not responded adequately to, other osteoporosis treatments.
Activella is a type of hormone therapy that combines an estrogen and a progestin.
Estradiol helps replace declining estrogen levels and relieve symptoms caused by estrogen deficiency. It also helps reduce bone loss after menopause.
Norethindrone acetate helps protect the uterine lining. Using estrogen alone in a woman who still has a uterus can cause the lining to grow too much and increase the risk of endometrial cancer. Adding a progestin helps lower this risk.
Activella does not permanently cure menopause symptoms or osteoporosis. It helps control symptoms and reduce bone loss while it is being taken.
Hormone therapy should generally be used at the lowest effective dose for the shortest period appropriate for the individual. A healthcare provider should regularly review whether continued treatment is still needed.
Take Activella exactly as directed by your healthcare provider. It is taken by mouth as one tablet once daily.
You may take Activella with or without food. Try to take it at approximately the same time each day to help you remember your dose and maintain consistent hormone levels.
Swallow the tablet with water. Do not take more than the prescribed amount or continue treatment longer than recommended.
The usual dose is one Activella tablet once daily.
Each standard-strength tablet contains:
Other strengths may be available, so always check your prescription label and follow the dose selected by your healthcare provider.
Your healthcare provider will choose the dose based on your symptoms, treatment goals, medical history, and response to therapy.
Hormone therapy should generally be used at the lowest effective dose for the shortest appropriate duration. Your healthcare provider should regularly review whether treatment is still needed.
Take Activella every day, even if you are not experiencing symptoms at the time of your dose.
Do not change the dose, skip treatment for long periods, or stop taking Activella without speaking with your healthcare provider.
Take a missed dose as soon as you remember. However, skip it if it is almost time for your next scheduled dose.
Continue with your regular dosing schedule. Do not take two tablets at the same time or take extra medication to replace a missed dose.
Activella (Estradiol/Norethindrone Acetate) is available in the following forms and strength:
Activella is a combination hormone therapy containing estrogen and progestin. Before starting treatment, a healthcare provider should review the possible benefits and risks based on your symptoms, age, medical history, and treatment goals.
Hormone therapy should generally be used at the lowest effective dose for the shortest appropriate period.
Activella may increase the risk of blood clots, stroke, heart attack, and other cardiovascular problems.
The risk may be higher if you:
Seek immediate medical care if you develop sudden chest pain, difficulty breathing, coughing up blood, swelling or pain in one leg, sudden weakness, difficulty speaking, or a sudden severe headache.
Using estrogen without a progestin can increase the risk of endometrial cancer in women who still have a uterus.
Activella contains norethindrone acetate, a progestin that helps reduce this risk. However, unusual or persistent vaginal bleeding should always be assessed by a healthcare provider.
Contact your healthcare provider if you experience bleeding after menopause, unusually heavy bleeding, or bleeding that continues or returns unexpectedly.
Long-term use of combined estrogen and progestin therapy may increase the risk of breast cancer.
Attend recommended breast examinations and mammograms. Tell your healthcare provider if you notice a breast lump, nipple discharge, skin changes, or any other unusual breast symptoms.
Combined hormone therapy may increase the risk of probable dementia when started in women aged 65 years or older.
Activella should not be used to prevent dementia or memory loss. Speak with a healthcare provider if you develop new or worsening problems with memory, thinking, or confusion.
Smoking while using estrogen-containing therapy can further increase the risk of blood clots, stroke, heart attack, and high blood pressure.
Tell your healthcare provider if you smoke or use tobacco. They can help determine whether Activella is appropriate and discuss support for stopping tobacco use.
Surgery, prolonged bed rest, and extended periods of sitting can increase the risk of blood clots. This includes long flights or car journeys.
Tell your healthcare provider about any planned surgery or period of limited mobility. You may be advised to stop Activella temporarily or take additional precautions.
Do not stop the medication unless your healthcare provider tells you to do so.
Activella may interact with certain medications and supplements. These interactions may affect hormone levels or increase the risk of side effects.
Tell your healthcare provider and pharmacist about all products you use, including:
Do not start, stop, or change another medication without medical advice.
Your healthcare provider should regularly review whether Activella is still needed and whether the benefits continue to outweigh the risks.
Attend all recommended follow-up appointments, blood pressure checks, breast screenings, and other examinations during treatment.
No. Activella may not be suitable for everyone. Before starting treatment, tell your healthcare provider about your medical history, including any history of blood clots, stroke, heart attack, liver disease, breast cancer, unexplained vaginal bleeding, or other hormone-sensitive conditions. Your healthcare provider will review the potential benefits and risks to determine whether Activella is appropriate for you.
Store Activella at room temperature in a dry place away from heat, moisture, and direct sunlight. Keep the tablets in their original container and store them out of the reach of children and pets. Do not keep Activella in a bathroom or another humid area. Do not use tablets that are damaged, expired, or stored incorrectly.
Yes. Activella can interact with certain medications and supplements. Tell your healthcare provider and pharmacist about all products you use, including prescription medications, nonprescription medicines, vitamins, herbal products, and dietary supplements. Some interactions may change hormone levels, reduce the effectiveness of Activella, or increase the risk of side effects. Do not start, stop, or change another medication without medical advice.
| Generic name: | Estradiol/Norethindrone Acetate |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 0.5/0.1mg, 1/0.5mg |
| Quantities Available: | 84 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Activella (estradiol/norethindrone acetate) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Activella is available in different strengths, typically in combinations such as 0.5 mg/0.1 mg or 1 mg/0.5 mg of estradiol/norethindrone acetate per tablet. The dosage and frequency of administration depend on the specific formulation and your healthcare provider’s recommendations.
For example: If prescribed one tablet daily of 0.5 mg/0.1 mg, for a 90-day supply, you would order 90 tablets (90 days x 1 tablet per day).
Yes, we sell estradiol/norethindrone acetate at our pharmacy, and you can enjoy low prices. However, to purchase estradiol/norethindrone acetate, you will need a valid prescription from your healthcare provider. We require this to dispense the medication safely and appropriately. You can provide your prescription by mailing, faxing, or uploading it through your online account.
Yes, we ship Activella (estradiol/norethindrone acetate) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Activella (Estradiol/Norethindrone Acetate). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Activella (Estradiol/Norethindrone Acetate).
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