Indications
Dostinex is a medication used to treat hyperprolactinemia, a condition characterized by elevated levels of prolactin hormone in the blood. It contains Cabergoline. Cabergoline belongs to a class of medications called dopamine receptor agonists. It works by blocking the release of prolactin from the pituitary gland.
Cabergoline works by reducing prolactin secretion, which can cause a variety of symptoms such as breast enlargement, reduced libido, and infertility women. By reducing the amount of prolactin in the body, Dostinex helps to treat hyperprolactinemia and other conditions associated with elevated levels of prolactin. Cabergoline is also sometimes used off-label to treat Parkinson's disease, although it is primarily used to treat hyperprolactinemia.
Uses and Dosage
Dostinex is typically available in tablet form to be taken by mouth with or without food, usually twice a week or as directed by your doctor. To prevent the production of breast milk, the recommended dose is two tablets taken as a single dose on the first day after delivery of your baby.
The dosage is based on your medical condition and response to treatment, and your doctor will start you at a low dose, gradually increasing your dose over several months to help decrease side effects. Follow your doctor's instructions carefully and take this medication regularly to get the most benefit from it. You can mark the days on the calendar when you need to take the medication to help you remember.
The recommended dosage of Dostinex (cabergoline) varies depending on the medical condition being treated.
- For the initiation of therapy for disorders of high prolactin levels or pituitary tumors in adults, the recommended starting dosage is 0.25 mg twice a week, which may be increased to a maximum of 1 mg twice a week.
- For postpartum lactation inhibition, the recommended dosage is 0.25 mg every 12 hours for 2 days, for a total dose of 1 mg. The dosage may be adjusted by your doctor based on your medical condition and response to treatment, with a gradual increase over several months to help decrease side effects.
Side Effect
Common Side Effects of Dostinex (Cabergoline):
- Nausea
- Dizziness
- Headache
- Lightheadedness
- Drowsiness
- Tiredness
- Vomiting
- Dry mouth
- Stomach upset
- Constipation
- Gas
Serious Side Effects of Dostinex (Cabergoline):
- Persistent cough
- Vision changes
- Breast pain
- Painful menses
- Mental or mood changes
- Strong urges
- Chest pain
- Changes in urine output
- Signs of heart failure (shortness of breath, swelling of extremities, unusual tiredness, sudden weight gain)
Form and Strength
Dostinex (Cabergoline) is available in the following forms and strength:
Dostinex: Tablet
- 0.5 mg
Cabergoline: Tablet
- 0.25 mg
- 0.5 mg
- 1 mg
Caution
- Dostinex may cause dizziness or fainting, especially when standing up from a sitting or lying down position. Avoid driving or operating machinery until you know how Dostinex affects you.
- Dostinex may interact with alcohol and cause adverse reactions. Consult with a healthcare provider before taking Dostinex to ensure safe and effective use.
- Uncontrolled hypertension or known hypersensitivity to ergot derivatives.
- Patients taking Dostinex should not drink alcohol, as it may increase the risk of adverse reactions.
- Dostinex has been associated with an increased risk of valvular heart disease. Patients with existing heart valve problems or a history of cardiac or pulmonary fibrotic disorders may need to have their heart function monitored closely while taking Dostinex.
- Dostinex can interact with certain medications, including drugs that affect serotonin levels in the brain. Patients should inform their healthcare provider of all medications they are taking before starting Dostinex.
- Dostinex should not be taken during pregnancy, as it may cause harm to an unborn baby.
- Patients should inform their healthcare provider if they have a history of mental health disorders, as Dostinex may affect mood and behavior in some individuals.
Frequently Asked Questions (FAQ)
Can Dostinex (Cabergoline) be taken during pregnancy?
Dostinex should not be taken during pregnancy, as it may harm an unborn baby. Consult with a healthcare provider if you are pregnant or planning to become pregnant before taking Dostinex.
How long does it take for Dostinex (Cabergoline) to work?
The onset of action of Dostinex varies depending on the medical condition being treated. It may take several weeks of treatment to achieve desired results for hyperprolactinemia, and up to several months for Parkinson's disease.
Can Dostinex (Cabergoline) be taken with food?
Yes, Dostinex can be taken with or without food.
Is Dostinex (Cabergoline) addictive?
Dostinex is not believed to be addictive in nature.
Can Dostinex (Cabergoline) be used in children?
Dostinex is not approved for use in children under the age of 16. Consult with a healthcare provider for more information about pediatric use.
How should Dostinex (Cabergoline) be stored?
Dostinex should be stored at room temperature, away from moisture and heat, and out of reach of children.
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