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Fetzima (Levomilnacipran) Shopper Approved

Prescription Prescription Required FormationFormulation: Capsule

Fetzima

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Prescription Prescription Required FormationFormulation: Capsule

Levomilnacipran

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Fetzima (active ingredient: levomilnacipran) is a prescription medication used to treat major depressive disorder (MDD) in adults.

Major depressive disorder is more than simply feeling sad or having a bad day. It is a medical condition that affects how you think, feel, and function in your daily life. Symptoms may include:

  • Persistent feelings of sadness, emptiness, or hopelessness.
  • Loss of interest in activities you once enjoyed.
  • Low energy or fatigue.
  • Changes in sleep or appetite.
  • Difficulty concentrating or making decisions.
  • Feelings of worthlessness or excessive guilt.

By treating depression, Fetzima can help improve your mood, increase your energy, restore interest in daily activities, and improve your overall quality of life. Because the medication works gradually, it may take several weeks before you notice its full benefits.

How Does Fetzima Work?

Fetzima belongs to a group of medications called serotonin and norepinephrine reuptake inhibitors (SNRIs).

It works by increasing the levels of two important brain chemicals called serotonin and norepinephrine, which help regulate mood, emotions, motivation, and the body’s response to stress.

People with depression may have an imbalance of these neurotransmitters. Fetzima helps restore this balance by preventing serotonin and norepinephrine from being reabsorbed too quickly by nerve cells, allowing more of these chemicals to remain available in the brain.

By increasing serotonin and norepinephrine levels, Fetzima may help:

  • Improve mood.
  • Reduce feelings of sadness and hopelessness.
  • Increase energy and motivation.
  • Improve concentration and mental focus.
  • Restore interest in everyday activities.

Fetzima does not work immediately. Some people may notice improvements in energy, sleep, or appetite within the first 1 to 2 weeks, but it may take 4 to 8 weeks or longer to experience the full antidepressant effects. Continue taking the medication exactly as prescribed, even if you do not feel better right away, unless your healthcare provider instructs you to stop.

Fetzima is available as an extended-release capsule that is taken by mouth once daily, exactly as prescribed by your healthcare provider.

You may take Fetzima with or without food. Try to take your dose at the same time each day to help maintain a consistent level of medication in your body and make it easier to remember.

Swallow the extended-release capsule whole with a full glass of water. Do not crush, chew, open, or split the capsule, as this can release the medication too quickly and increase the risk of side effects.

Your healthcare provider will determine the right dose based on:

  • Your medical condition.
  • How well you respond to treatment.
  • Any side effects you experience.
  • Other medications you may be taking.

Always take Fetzima exactly as prescribed. Do not take more or less than the recommended dose, and do not change your dosing schedule without first consulting your healthcare provider.

Important Tips

  • Take Fetzima once a day at the same time each day.
  • The capsules may be taken with or without food.
  • If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
  • Continue taking Fetzima even if you begin to feel better. It may take several weeks before you experience the full benefits of treatment.
  • Do not stop taking Fetzima suddenly. Abruptly discontinuing the medication may cause withdrawal symptoms such as headache, dizziness, fatigue, irritability, nausea, or a tingling sensation. If treatment needs to be stopped, your healthcare provider will gradually lower your dose to help reduce the risk of withdrawal symptoms.
  • If you have any questions about your dose or how to take Fetzima, speak with your healthcare provider or pharmacist before making any changes.

Common Side Effects of Fetzima (Levomilnacipran):

  • Constipation
  • Dizziness
  • Dry mouth
  • Fatigue
  • Increased heart rate
  • Insomnia
  • Nausea
  • Sweating

Serious Side Effects of Fetzima (Levomilnacipran):

  • Easy bruising and bleeding
  • Eye pain
  • High blood pressure or hypertension
  • Painful urination
  • Pounding heartbeat
  • Problem initiating the flow of urine
  • Seizures
  • Signs of gastrointestinal bleeding (vomit that contains blood, black or bloody stool, dizziness)
  • Signs of low level of sodium or hyponatremia (nausea, mental or mood changes, drowsiness)
  • Sudden weight gain
  • Symptoms of serotonin syndrome (unexplained fever, restlessness, loss of coordination, fast heartbeat, hallucinations, twitching muscles)
  • Vision changes
  • Widened pupils

Fetzima (Levomilnacipran) is available in the following forms and strength:

Fetzima: Capsule

  • 20 mg
  • 40 mg
  • 80 mg
  • 120 mg

Before taking Fetzima, tell your healthcare provider about your complete medical history and all medications you are taking. This helps ensure the medication is safe for you and reduces the risk of serious side effects.

Suicidal Thoughts and Behavior

Like other antidepressants, Fetzima may increase the risk of suicidal thoughts or behaviors, particularly in children, adolescents, and young adults up to 24 years of age during the first few months of treatment or after a dose change.

You and your caregivers should watch closely for any unusual changes in mood or behavior, including:

  • New or worsening depression.
  • Thoughts of self-harm or suicide.
  • Increased anxiety or panic attacks.
  • Agitation or irritability.
  • Aggressive or impulsive behavior.
  • Trouble sleeping.
  • Unusual mood or behavior changes.

Contact your healthcare provider immediately if any of these symptoms occur. Seek emergency medical attention if suicidal thoughts or actions develop.

Serotonin Syndrome

Fetzima may cause serotonin syndrome, a rare but potentially life-threatening condition, especially if it is taken with other medications that increase serotonin levels.

Symptoms may include:

  • Agitation or restlessness.
  • Hallucinations.
  • Confusion.
  • Rapid heartbeat.
  • Fever.
  • Muscle stiffness or twitching.
  • Loss of coordination.
  • Severe nausea, vomiting, or diarrhea.

In severe cases, serotonin syndrome can lead to seizures, coma, or death. Seek emergency medical attention immediately if you develop symptoms of this condition.

Increased Blood Pressure and Heart Rate

Fetzima may increase your blood pressure and heart rate.

Before starting treatment, and periodically during therapy, your healthcare provider may check your blood pressure and pulse, especially if you have:

  • High blood pressure.
  • Heart disease.
  • An irregular heartbeat.
  • Other cardiovascular conditions.

Tell your healthcare provider if you experience chest pain, palpitations, severe headaches, dizziness, or shortness of breath.

Drug Interactions

Fetzima may interact with many medications, including:

  • Prescription medications.
  • Over-the-counter medicines.
  • Vitamins.
  • Herbal supplements.

Before starting Fetzima, provide your healthcare provider with a complete list of everything you take so they can check for potential drug interactions.

Do Not Stop Fetzima Suddenly

Do not stop taking Fetzima without first talking to your healthcare provider.

Stopping the medication abruptly may cause withdrawal symptoms, including:

  • Agitation.
  • Irritability.
  • Trouble sleeping (insomnia).
  • Confusion.
  • Headache.
  • Dizziness.
  • Fatigue.

If treatment needs to be discontinued, your healthcare provider will gradually reduce your dose to help minimize withdrawal symptoms.

Low Sodium Levels (Hyponatremia)

Fetzima may cause hyponatremia (low sodium levels in the blood), particularly in older adults and people taking diuretics (“water pills”).

Symptoms of low sodium may include:

  • Headache.
  • Confusion.
  • Weakness.
  • Difficulty concentrating.
  • Loss of balance.
  • Seizures in severe cases.

Contact your healthcare provider if you develop any of these symptoms.

Drowsiness and Impaired Alertness

Fetzima may affect your ability to think clearly or react quickly. It may cause:

  • Dizziness.
  • Drowsiness.
  • Difficulty concentrating.

Until you know how Fetzima affects you, avoid driving, operating machinery, or performing activities that require alertness.

Seizures

Use Fetzima with caution if you have a history of seizures or epilepsy, as it may lower the seizure threshold and increase the risk of seizures.

Tell your healthcare provider if you have ever had a seizure disorder before starting treatment.

Liver Problems

Although uncommon, Fetzima may affect liver function.

Contact your healthcare provider if you develop symptoms of liver problems, such as:

  • Yellowing of the skin or eyes (jaundice).
  • Dark-colored urine.
  • Severe fatigue.
  • Persistent nausea or vomiting.
  • Pain in the upper right side of your abdomen.

Urinary Retention and Narrow-Angle Glaucoma

Fetzima should be used with caution if you have a history of urinary retention, difficulty urinating, or narrow-angle glaucoma.

Tell your healthcare provider before starting treatment if you have either of these conditions, as Fetzima may worsen them.

How long does Fetzima take to work?

Fetzima does not work immediately. Some people may notice improvements in symptoms such as energy, sleep, or appetite within the first 1 to 2 weeks of treatment. However, it may take 4 to 8 weeks or longer to experience the full antidepressant benefits. Continue taking Fetzima exactly as prescribed, even if you do not notice improvement right away, unless your healthcare provider instructs you otherwise.

Can Fetzima cause weight loss?

Yes. Some people may experience weight loss while taking Fetzima, although this side effect is generally uncommon and is usually modest. If you notice significant or unexpected changes in your weight, talk to your healthcare provider. They can determine whether the medication may be contributing to the change and discuss appropriate management options if needed.

Can Fetzima be used to treat anxiety?

Fetzima is approved only for the treatment of major depressive disorder (MDD) in adults. It is not approved by the U.S. Food and Drug Administration (FDA) to treat anxiety disorders. However, in some cases, healthcare providers may prescribe Fetzima off-label if they believe it may be beneficial for an individual patient.

Can Fetzima be used in children?

No. Fetzima is not approved for use in children or adolescents younger than 18 years of age. Its safety and effectiveness have not been established in this age group.

Who should not take Fetzima?

Do not take Fetzima if you are allergic to levomilnacipran or any of the ingredients in the medication. You should also not take Fetzima if you are currently taking a monoamine oxidase inhibitor (MAOI) or if you have taken an MAOI within the past 14 days, as combining these medications can increase the risk of serotonin syndrome, a potentially life-threatening condition. Before starting Fetzima, tell your healthcare provider about all the medications you are taking so they can determine whether the medication is safe for you.

Can Fetzima be taken during pregnancy?

If you are pregnant, planning to become pregnant, or breastfeeding, tell your healthcare provider before taking Fetzima. The safety of Fetzima during pregnancy has not been fully established. Your healthcare provider will carefully weigh the potential benefits and risks before recommending this medication during pregnancy. Do not start or stop taking Fetzima while pregnant without first consulting your healthcare provider.

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Additional Information Book
Generic name:

Levomilnacipran

Formulation:

Capsule

Strength(s):

20mg, 40mg, 80mg, 120mg

Quantities Available:

30, 60, 90

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Fetzima can I order at once from a Canadian pharmacy?

When ordering Fetzima (levomilnacipran) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is standard for many prescription medications to ensure continuous treatment without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Fetzima is commonly prescribed in dosages of 20 mg, 40 mg, 80 mg, and 120 mg, taken once daily. For a 90-day supply, this means you would order 90 capsules (90 days x 1 capsule per day).

Do you sell levomilnacipran?

Yes, we sell levomilnacipran on our website, and you can enjoy competitive prices. However, please note that you will need a valid prescription from your healthcare provider to purchase this medication. We require a prescription to dispense the medication safely and responsibly. You can conveniently provide your prescription by mailing, faxing, or uploading it through your online account during the ordering process.

Do you offer shipping of Fetzima (levomilnacipran) to the United States?

Yes, we ship Fetzima (levomilnacipran) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Fetzima (Levomilnacipran). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Fetzima (Levomilnacipran).