Indications
Dipentum is a medication used to treat ulcerative colitis, a type of inflammatory bowel disease. It contains active ingredient called olsalazine, which belongs to the group of medications known as anti-inflammatories. Olsalazine works by reducing inflammation in the lining of the colon.
Dipentum does not cure ulcerative colitis, but it may decrease symptoms such as diarrhea, rectal bleeding, and stomach pain. It can be used to prevent attacks of the disease, and for the long-term maintenance of remission for people with ulcerative colitis.
Use and Dosage
Dipentum is an oral tablet that should be taken as directed by your doctor, typically twice a day, 12 hours apart. Taking the tablets with food or after meals can help prevent stomach upset. To prevent kidney stones, drink plenty of fluids during treatment unless told otherwise by your doctor.
The recommended adult dose for treatment of attacks is usually increased slowly over a one-week period starting with 500 mg daily and increasing to an average adult dose of 2 tablets 4 times daily. The recommended adult dose for prevention of attacks is 500 mg (2 Tablet) 2 times daily. The dose for children is based on the age and weight of the child.
Take olsalazine at regular intervals together with meals. Do not take more than 1 g at any one time. This medication should be taken in evenly divided doses. Taking the medication at the same time each day can help ensure the most benefit. If your condition does not improve or worsens while taking Dipentum, be sure to inform your doctor right away.
Side Effects
Common Side Effects of Dipentum (Olsalazine):
- Diarrhea
- Headache
- Itching
- Joint pain
- Rash
- Stomach pain
- Upset stomach
Serious Side Effects of Dipentum (Olsalazine):
- Blood in your urine
- Bloody diarrhea
- Chest pain
- Chills
- Clay-colored stools
- Cold hands and feet
- Cramping
- Dark urine
- Difficulty breathing
- Easy bruising
- Fast or pounding heartbeats
- Fever
- Hives
- Lightheadedness
- Loss of appetite
- Mouth sores
- Pain or burning when you urinate
- Pale skin
- Severe or ongoing diarrhea
- Shortness of breath
- Skin sores
- Stomach pain
- Sudden and severe pain in your lower back or side
- Swelling of your face lips tongue or throat
- Tiredness
- Unusual bleeding
- Yellowing of the skin or eyes
Forms and Strength
Dipentum (Olsalazine) is available in the following forms and strength:
Dipentum: Tablet
- 250 mg
Cautions
- Allergic reactions: Dipentum may cause serious allergic reactions, including hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. Seek immediate medical attention if you experience any of these symptoms.
- Blood problems: Dipentum may cause blood problems, such as agranulocytosis, neutropenia, or pancytopenia. These conditions can increase the risk of infections and may be life-threatening. Patients should have their blood counts monitored regularly while taking Dipentum.
- Liver problems: Dipentum can affect liver function. Patients with liver problems or a history of liver disease should be closely monitored while taking Dipentum.
- Kidney problems: Dipentum can affect kidney function. Patients with kidney problems or a history of kidney disease should be closely monitored while taking Dipentum.
- Sun sensitivity: Dipentum may increase sensitivity to sunlight and increase the risk of sunburn, particularly in patients with eczema or other skin problems. Patients should use sunscreen and avoid prolonged exposure to sunlight while taking Dipentum.
- Interactions with other drugs: Dipentum may interact with other drugs, including blood thinners, antacids, and certain antibiotics. Patients should inform their doctor or pharmacist about all medications they are currently taking to avoid potentially harmful interactions.
- Pregnancy and breastfeeding: The effects of Dipentum on pregnant or breastfeeding women are not well-studied. Women who are pregnant or breastfeeding should talk to their doctor about the potential risks and benefits of taking Dipentum.
- Pediatric use: The safety and effectiveness of Dipentum in children younger than 2 years of age have not been established. Children taking Dipentum should be closely monitored by a healthcare professional.
- Elderly patients: Elderly patients may be more susceptible to the side effects of Dipentum and should be monitored closely by a healthcare professional.
Frequently Asked Questions (FAQ)
Can Dipentum (Olsalazine) be used to treat other conditions?
No, Dipentum (Olsalazine) is only used to treat ulcerative colitis and is not approved for use in treating other conditions.
What should I do if I miss a dose of Dipentum (Olsalazine)?
If you miss a dose of Dipentum (Olsalazine), take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Can alcohol be consumed while taking Dipentum (Olsalazine)?
There is no known interaction between Dipentum (Olsalazine) and alcohol. However, patients with ulcerative colitis should limit or avoid alcohol consumption as it can worsen symptoms.
Does Dipentum (Olsalazine) need to be taken with food?
Dipentum (Olsalazine) can be taken with or without food. Patients should follow their doctor's instructions regarding the best way to take the medication.
Resources
- https://www.medbroadcast.com/drug/getdrug/dipentum
- https://www.drugs.com/mtm/dipentum.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019715s029lbl.pdf
- https://www.rxlist.com/dipentum-drug.htm
- https://www.webmd.com/drugs/2/drug-14039/dipentum-oral/details
- https://www.goodrx.com/dipentum/what-is
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