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Colazal (active ingredient: balsalazide disodium) is a prescription anti-inflammatory medication used to treat mildly to moderately active ulcerative colitis in adults and children 5 years of age and older. It belongs to a group of medicines called aminosalicylates.
Ulcerative colitis is a type of inflammatory bowel disease that causes ongoing inflammation and sores in the lining of the colon and rectum.
During a flare, the inflammation may lead to symptoms such as:
The severity of symptoms can vary from person to person.
Mild to Moderate Active Ulcerative Colitis
Colazal is used to treat mild to moderate ulcerative colitis when the condition is active.
The goal of treatment is to reduce inflammation in the colon and improve symptoms such as diarrhea, rectal bleeding, abdominal discomfort, and bowel urgency.
Helps Control an Ulcerative Colitis Flare
During an active flare, inflammation in the lining of the colon becomes more severe.
Colazal helps calm this inflammation. As the colon begins to heal, symptoms such as bleeding, diarrhea, and abdominal pain may improve.
Helps Improve Bowel Symptoms
By reducing inflammation in the colon, Colazal may help decrease the frequency and urgency of bowel movements and reduce discomfort associated with active ulcerative colitis.
The amount of improvement can vary depending on the severity of the condition and the person’s response to treatment.
How Colazal Works
Colazal is an aminosalicylate that is designed to deliver its active anti-inflammatory component mainly to the colon.
Balsalazide is known as a prodrug. This means the medication is converted into its active form after it reaches the colon.
Bacteria naturally found in the colon break balsalazide down and release mesalamine, also known as 5-aminosalicylic acid or 5-ASA. Mesalamine then acts directly on the lining of the colon.
Mesalamine helps decrease inflammatory activity in the intestinal lining.
Reducing inflammation can help relieve several symptoms of active ulcerative colitis, including diarrhea, rectal bleeding, and abdominal discomfort.
Colazal is designed so that much of its active anti-inflammatory effect occurs in the colon rather than earlier in the digestive tract.
This targeted delivery allows mesalamine to act directly on the inflamed tissues associated with ulcerative colitis.
Colazal does not usually provide immediate symptom relief after a single dose.
Improvement generally occurs as inflammation in the colon decreases with regular treatment. How quickly you respond can depend on the severity of your ulcerative colitis and your individual response to balsalazide.
Continue taking Colazal exactly as prescribed, even if you begin to feel better.
For adults, the safety and effectiveness of balsalazide treatment beyond 12 weeks have not been established. For children and adolescents 5 to 17 years of age, safety and effectiveness beyond 8 weeks have not been established.
Your healthcare provider will determine how long treatment should continue based on your symptoms and response.
No. Colazal helps control inflammation and symptoms, but it does not cure ulcerative colitis.
Ulcerative colitis is a long-term condition that may include periods when symptoms improve and periods when they return.
Your healthcare provider may recommend additional treatment or monitoring depending on the course of your condition.
Take Colazal exactly as prescribed by your healthcare provider. Do not increase, reduce, or stop your medication without medical advice.
Contact your healthcare provider if your ulcerative colitis symptoms become worse, you develop significant rectal bleeding, or your symptoms do not improve during treatment.
Colazal comes as a 750 mg capsule that is taken by mouth. It is usually taken three times daily to treat mildly to moderately active ulcerative colitis.
Colazal can be taken with or without food. Take each dose exactly as prescribed by your healthcare provider.
Most Colazal treatment schedules require three doses each day.
Try to take your doses at about the same times every day. A regular schedule can make it easier to remember your medication and maintain consistent treatment throughout the day.
Do not take more capsules or take them more often than prescribed.
Colazal can be taken with meals or on an empty stomach.
If you experience stomach discomfort, ask your healthcare provider whether taking the capsules with food may help.
If you can swallow the capsules comfortably, swallow them whole with water.
Do not cut, break, crush, or chew an intact capsule.
If you cannot swallow a Colazal capsule whole, it may be opened and mixed with applesauce.
Place about 10 mL of applesauce in a clean container. Carefully open the prescribed capsules and sprinkle the contents onto the applesauce.
Mix the contents and consume the entire mixture immediately. Do not save it for a later dose.
The mixture may be swallowed or chewed if necessary. Some people may notice temporary staining of the teeth or tongue when the capsule contents are taken this way.
Drink an adequate amount of fluids while taking Colazal unless your healthcare provider has told you to limit your fluid intake.
Balsalazide and related medicines can be associated with kidney stones, so staying properly hydrated is important during treatment.
For adults with mildly to moderately active ulcerative colitis, the recommended dose is:
2.25 grams three times daily
Each dose consists of three 750 mg capsules.
This means an adult taking the standard dose receives:
Treatment is generally given for up to 8 weeks. Some adults in clinical trials required treatment for as long as 12 weeks. Safety and effectiveness beyond 12 weeks have not been established.
For children and adolescents between 5 and 17 years of age, there are two recommended dosing options.
One option is 2.25 grams three times daily, which equals three 750 mg capsules per dose and a total of 6.75 grams per day.
The other option is 750 mg three times daily, which equals one capsule per dose and a total of 2.25 grams per day.
The healthcare provider will determine which dosing schedule is appropriate.
Treatment in children is generally limited to 8 weeks because safety and effectiveness beyond this period have not been established.
The safety and effectiveness of balsalazide have not been established in children younger than 5 years of age.
Do not give Colazal to a young child unless specifically directed by a healthcare provider.
The length of treatment depends on your age, symptoms, and response to therapy.
Adults are commonly treated for up to 8 weeks, although some may require treatment for up to 12 weeks. Children ages 5 to 17 are generally treated for up to 8 weeks.
Continue taking Colazal for the period recommended by your healthcare provider, even if your diarrhea, rectal bleeding, or abdominal discomfort begins to improve.
Do not stop treatment early without medical advice.
If you forget a dose of Colazal, take it when you remember unless it is almost time for your next dose.
If your next scheduled dose is close, skip the missed dose and continue with your normal schedule.
Do not take two doses at the same time to make up for a missed dose.
Your healthcare provider should evaluate your kidney function before you start balsalazide and periodically during treatment.
This is particularly important if you already have kidney disease or take medicines that can affect kidney function.
The statement that the maximum daily dose is 2.25 grams, or three capsules per day, does not apply to all patients.
The standard adult regimen is 6.75 grams per day, which equals nine 750 mg capsules.
For children ages 5 to 17, either 2.25 grams per day or 6.75 grams per day may be prescribed.
Take Colazal exactly as prescribed by your healthcare provider. Do not increase or decrease your dose on your own.
Take the medication consistently, drink adequate fluids, and contact your healthcare provider if your ulcerative colitis symptoms become worse, do not improve, or you experience new or concerning side effects.
Colazal (Balsalazide) is available in the following forms and strength:
Some people may have an allergic reaction to Colazal.
Symptoms may include rash, itching, swelling, or difficulty breathing. Stop taking the medication and seek immediate medical attention if you develop signs of a serious allergic reaction.
Colazal may rarely affect liver function.
Contact your healthcare provider if you develop unusual tiredness, abdominal pain, dark urine, or yellowing of the skin or eyes. These may be signs of a liver problem.
Colazal may also affect kidney function in some people.
Tell your healthcare provider if you have kidney disease before starting treatment. Contact your healthcare provider if you notice decreased urination, swelling in the legs or feet, or other unusual changes.
In rare cases, Colazal may affect blood cell counts.
Possible problems may include anemia or a low platelet count. Contact your healthcare provider if you develop unusual tiredness, pale skin, frequent bruising, or unusual bleeding.
Colazal may interact with certain medicines.
Before starting treatment, tell your healthcare provider about all prescription medicines, over-the-counter products, vitamins, and herbal supplements you take.
Check with your healthcare provider or pharmacist before starting any new medication while taking Colazal.
There is no specific alcohol prohibition in the Colazal prescribing information. However, alcohol may irritate the digestive system and could make symptoms such as diarrhea or abdominal discomfort worse in some people with ulcerative colitis. Ask your healthcare provider whether alcohol is appropriate for you while taking Colazal.
Colazal may interact with certain medications. Before starting Colazal, tell your healthcare provider about all prescription medicines, over-the-counter products, vitamins, and herbal supplements you take. Check with your healthcare provider or pharmacist before starting any new medication during treatment.
If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Colazal works by reducing inflammation in the colon, so improvement may not happen immediately. Some people may notice their ulcerative colitis symptoms improving gradually during treatment. Continue taking Colazal exactly as prescribed, even if you do not notice immediate relief. Contact your healthcare provider if your symptoms do not improve or become worse.
Yes. Colazal capsules can be taken with or without food. If the medication causes stomach discomfort, ask your healthcare provider whether taking it with food may help.
Colazal comes as a capsule, not a tablet. If you have difficulty swallowing the capsule whole, you may open it and sprinkle the contents onto applesauce. Consume the mixture immediately and do not store it for later use. Follow the instructions provided by your healthcare provider or pharmacist.
Store Colazal at controlled room temperature and protect it from excess moisture. Keep the medication in its original container and out of the reach of children. Follow any additional storage instructions provided on your prescription label.
| Generic name: | Balsalazide |
|---|---|
| Formulation: | Capsule, Tablet |
| Strength(s): | 750mg |
| Quantities Available: | 100, 130 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Colazal (balsalazide) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Colazal is commonly prescribed in dosages of 750 mg taken three times daily. For a 90-day supply, this means you would order 270 capsules (90 days x 3 capsules per day).
Yes, we sell balsalazide at our pharmacy, and you can enjoy low prices. However, to purchase balsalazide, you will need a valid prescription from your healthcare provider. We require this to dispense the medication safely and appropriately. You can provide your prescription by mailing, faxing, or uploading it through your online account.
Yes, we ship Colazal (balsalazide) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Colazal (Balsalazide). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Colazal (Balsalazide).
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