Differin Gel (Adapalene)

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Differin Gel Brand
Dosage Quantity & Price
Adapalene (Generic alternate to Differin Gel) Generic
Dosage Quantity & Price
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Adapalene is a topical medication used to treat a variety of skin conditions, such as acne and psoriasis. It is chemically related to vitamin A and works by affecting the growth of skin cells. It is a safe and effective treatment for mild and severe forms of acne and other forms of inflammatory skin disease.

Adapalene works by unblocking pores and reducing the number of spots that can form. It indicated in prescription treatments, allowing access to those with milder cases of acne. Adapalene is also known for its anti-inflammatory properties which help to reduce any redness or inflammation associated with blemishes.

Differin Gel is an acne treatment that contains an active ingredient called adapalene, which is a type of retinoid. It works by helping to unclog pores and reduce inflammation, which helps clear up and prevent breakouts.

Uses and Dosage

Adapalene comes in the form of a gel, and it should be applied directly to the skin as directed by your doctor or the product package, usually once daily at bedtime. Before applying the medication, gently clean the affected skin with a mild or soapless cleanser and pat dry.

When applying the gel, it is important to wash your hands before and after applying the medication. You can use your fingertips to apply a small amount of medication in a thin layer to the affected area. If you are using a medicated swab, make sure to unwrap the swab and apply a thin layer of the medication to the affected area

Use this medication on the skin only. Avoid getting it in your eyes or on your lips. Do not apply to the inner lip area or inside the nose/mouth. If it gets into your eyes, flush with large amounts of water. Call your doctor if eye irritation develops. Do not apply to cut, scraped, or sunburned areas, or to skin affected by eczema.

Side effect

Common Side Effects of Adapalene:

  • Dryness
  • Scaling
  • Burning/stinging
  • Erythema
  • Skin discomfort
  • Pruritus
  • Desquamation
  • Sunburn

Allergic Reactions of Adapalene:

  • Dryness
  • Itching
  • Mild burning
  • Scaling
  • Skin redness
  • Worsening of acne may occur during the first 2-4 weeks of using the medication.

Form and strength

Differin Gel (Adapalene) is available in the following forms and strength:

Differin Gel: Gel

  • 0.1%

Adapalene: Gel

  • 0.1%


  • Before using adapalene, tell your doctor or pharmacist if you are allergic to it, other retinoids such as isotretinoin, or any other allergies. Ask your pharmacist about inactive ingredients that may cause allergic reactions.
  • Women who are pregnant or may become pregnant should not use Differin Gel, as it is absorbed through the skin and may harm an unborn baby
  • Adapalene can make your skin more sensitive to ultraviolet (UV) light from the sun and other sources, such as sunlamps. To minimize the risk of sunburn and other skin reactions, it is important to use sunscreen and protective clothing when exposed to UV light.
  • When using Differin Gel, avoid electrolysis, waxing, and chemical depilatories for hair removal on the treated areas.
  • When using Differin Gel, avoid application to the areas of skin around the eyes, lips, and mucous membranes.
  • When using Differin Gel, avoid waxing the treated area or applying other topical products that may further irritate the skin, such as astringents, abrasive soaps, and cleansers, exfoliants, sulfur, resorcinol, and salicylic acid.

Frequently Asked Questions (FAQ)

How do I use Differin Gel?

Before you begin using Differin Gel, it is important to cleanse your skin with a gentle cleanser and pat it dry. Then, apply a thin layer of gel over your entire face, avoiding the eye area. Allow the gel to absorb into your skin before applying additional products.

How often should I use Differin Gel?

Differin Gel should be used once daily, preferably in the evening before bed.

Can I use makeup after applying Differin Gel?

Yes, you can apply makeup after applying Differin Gel, but you should wait at least 10 minutes after applying the gel before applying makeup.

How long does it take for Differin Gel to work?

Differin Gel should start to work within 12 weeks, but this can vary from person to person.

Are there any other products I should avoid when using Differin Gel?

Yes, avoid using any other topical retinoids, exfoliants, or products that contain alcohol, menthol, peppermint, or eucalyptus while using Differin Gel.

Does Differin Gel have any drug interactions?

Yes, Differin Gel may interact with certain drugs, such as antibiotics, sulfa drugs, and corticosteroids. Consult your doctor before taking any medication while using Differin Gel.


It's important to purchase Differin Gel from verified Canadian pharmacy.

Additional information

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