Indications
Corlanor (active ingredient: ivabradine) is a prescription medication indicated for:
- Treatment of Chronic Heart Failure (CHF): Corlanor is used to reduce the risk of hospitalization for worsening heart failure in patients with stable, symptomatic chronic heart failure (CHF) with an ejection fraction of less than or equal to 35%, who are in sinus rhythm with a resting heart rate of 70 beats per minute (bpm) or greater, and are either unable to tolerate or have a contraindication to beta-blockers.
Corlanor belongs to the drug class known as hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers.
Uses and Dosage
Ivabradine comes as a tablet to take by mouth. It is usually taken with food twice a day. Take ivabradine at around the same time every day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand. Take ivabradine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
- The typical dosing for Corlanor (ivabradine) for adults is 5 mg by mouth twice a day with food, which can be increased to a maximum of 7.5 mg if needed.
- For children over 6 months old and weighing less than 88 pounds (40 kg), the typical dose is 0.05 mg/kg by mouth twice a day with food, up to a maximum dose of 7.5 mg twice a day.
- For children weighing more than 88 pounds (40 kg), the typical starting dose is 2.5 mg by mouth twice a day with food, which can be increased to a maximum of 7.5 mg if needed.
Side Effects
Signs of an Allergy of Ivabradine:
- Swelling of the face and neck
- Hives
- Itching
- Rashes
- If severe, you may also experience:
- Severe dizziness
- Wheezing
- Trouble breathing
Common Side Effects of Corlanor:
- Dizziness or lightheadedness
- Flashes of light in your vision
- High blood pressure
- Increased or high blood pressure
- Irregular heartbeats
- Slow heart rate or bradycardia
Serious Side Effects of Corlanor
- Blurred vision
- Chest pain or discomfort
- Continuous high blood pressure
- Fainting
- Fast or irregular heartbeat
- Nervousness
- Pounding in the ears
- Slow or irregular heartbeat
- Unusual tiredness
- Unusual weakness or fatigue
Form and Strength
Corlanor (Ivabradine) is available in the following forms and strengths:
Corlanor: Tablet
- 5 mg
- 7.5 mg
Ivabradine: Tablet
- 5 mg
- 7.5 mg
Caution
- Avoid taking Corlanor (ivabradine) during pregnancy, as it may cause fetal toxicity and birth defects. Before starting Corlanor, take a pregnancy test and to use a reliable form of birth control while taking the medication. If you become pregnant while taking Corlanor, speak to your healthcare provider right away.
- Be aware that taking Corlanor (ivabradine) may increase your risk of developing a heart rhythm problem called atrial fibrillation (A. fib). A. fib can raise your risk of blood clots, strokes, and heart attacks.
- Taking Corlanor (ivabradine) can slow down your heart rate. This can be beneficial in some cases, but if your heart rate gets too slow, it can lead to serious heart rhythm conditions. Monitor your heart rate and blood pressure at home, as instructed by your healthcare provider. If you ever experience dizziness, extreme fatigue, or an extremely low heart rate or blood pressure, let your healthcare provider know right away.
- Corlanor (ivabradine) should be used with caution in patients with low blood pressure, liver problems, or other heart problems.
- It should be used with caution in patients with severe renal impairment or those who depend on a pacemaker to control their heart rate.
- Be aware that Corlanor (ivabradine) can interact with many medications and grapefruit juice.
Frequently Asked Questions (FAQ)
How much does Corlanor (ivabradine) lower the heart rate by?
Everyone has a slightly different reaction to Corlanor (ivabradine), and it depends on how high your heart rate is before you start taking this medication. The goal is to lower your resting heart rate to between 50 and 60 beats per minute.
Why do I need to take this Corlanor (ivabradine) with food?
Taking Corlanor (ivabradine) with food will help your body absorb the medication better. The more medication your body absorbs, the better it will work for you.
When is the best time to take ivabradine?
Ivabradine is taken 2 times a day, in the morning and in the evening. If you miss a dose and it is more than 4 hours until your next dose, take the missed dose then take your usual dose at the usual time.
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