Banzel (Rufinamide)

Indications

Banzel is a prescription medication approved by the FDA to treat seizures in patients with Lennox-Gastaut Syndrome (LGS). It contains the active ingredient rufinamide. Rufinamide is in a class of medications called anticonvulsants. It works by acting on the sodium channels in the brain that may cause seizures. Banzel is taken with other medications to prevent or control seizures associated with LGS.

Uses and Dosage

Banzel is an oral tablet medication that is generally taken with food, usually twice a day at around the same time every day. The tablets may be swallowed whole, broken in half on the score mark, or crushed. While the tablet may help control your condition, it will not cure it. Even if you feel well, continue taking Banzel, and do not stop suddenly without consulting your doctor. If you suddenly stop taking Banzel, your seizures may worsen. Your doctor will likely decrease your dose gradually.

Generally, your doctor will begin with a low dose of Banzel and gradually increase your dose, but not more than once every other day. Take the tablet exactly as directed by your doctor, neither more nor less, nor more often than prescribed.

The recommended starting daily dose of Banzel in adults with Lennox-Gastaut Syndrome is 400 to 800 mg per day administered in two equally divided doses. The target dosage was achieved in 88% of patients, and most patients reached the target dose within 7 days. However, the specific dosage may be adjusted based on the patient's needs and response to the medication.

Side effect

Common Side Effects of Banzel (Rufinamide):

• Back pain
• Difficulty paying attention
• Difficulty walking
• Dizziness
• Excessive movement or activity
• Headache
• Loss of appetite
• Loss of coordination
• Nausea
• Sleepiness
• Stomach pain
• Uncontrollable movements of the eyes
• Uncontrollable shaking of a part of the body
• Vomiting

Serious Side Effects of Banzel (Rufinamide):

• Blurred or double vision
• Dark-colored urine
• Decreased ability to respond to others
• Fever
• Hives
• Itching
• Light-colored stool
• Rash
• Seizures
• Swelling of the face
• Yellowing of the skin or eyes

Form and strength

Banzel (Rufinamide) is available in the following forms and strength:

Banzel: Scored Film Coated Tablet

• 200 mg
• 400 mg

Caution

• Banzel may cause dizziness, fatigue, and problems with coordination, which can impair your ability to drive or operate heavy machinery. Consult with your doctor if you experience these side effects.
• Consuming alcohol while taking Banzel can increase the risk of side effects such as drowsiness, dizziness, and coordination problems. Consult with your doctor before consuming alcohol while taking Banzel.
• Do not suddenly stop taking Banzel without talking to your doctor. Doing so can cause a sudden increase in seizures. Your doctor will likely decrease your dose gradually over time.
• Banzel can interact with other medications, consult your doctor or pharmacist about all medications you are taking before starting Banzel.
• The use of Banzel while pregnant or breastfeeding is not recommended unless the potential benefits outweigh the risks.
• Banzel may cause changes in mood or behavior, such as suicidal thoughts or suicidal behavior.
• Patients with a history of depression, mood disorders, or suicidal thoughts should be closely monitored while taking Banzel.
• Banzel may lower the effectiveness of hormonal birth control, use backup contraception methods while taking Banzel.
• Banzel may cause an allergic reaction in some people. Seek medical attention immediately if you experience symptoms such as swelling, difficulty breathing, or hives.
• People with liver or kidney problems should use Banzel with caution and may need a lower dosage.
• Contact your doctor immediately if you experience any severe side effects or have concerns about the medication.

Frequently Asked Questions (FAQ)

What should I do if I miss a dose of Banzel (Rufinamide)?

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, do not take the missed dose and continue with your regular dosing schedule. Do not take extra doses to make up for missed ones.

Can I take Banzel (Rufinamide) while pregnant or breastfeeding?

The use of Banzel while pregnant or breastfeeding is not recommended unless the potential benefits outweigh the risks. Consult your doctor if you are pregnant or breastfeeding and considering the use of Banzel.

Can Banzel (Rufinamide) interact with other medications?

Yes, Banzel can interact with other medications, including birth control pills and some medications used to treat depression, anxiety, or pain. Be sure to tell your doctor or pharmacist about all medications you are taking before starting Banzel.

How long does it take for Banzel (Rufinamide) to start working?

The length of time it takes for Banzel to start working can vary from person to person, but it usually takes a few weeks for the full effects to be noticed.

Resources

• https://medlineplus.gov/druginfo/meds/a609001.html
• https://www.drugs.com/banzel.html
• https://www.medicalnewstoday.com/articles/banzel
• https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0a3fa925-1abd-458a-bd57-4ae780a1ef2d
• https://www.banzel.com/
• https://www.webmd.com/drugs/2/drug-151652/banzel-oral/details