Skip to main content

Aklief Cream (Trifarotene) Shopper Approved

Prescription Prescription Required FormationFormulation: Cream

Aklief Cream

(Brand Option)

Select the prescribed dosage

Select the quantity to see the price.

  *  
Prescription Prescription Required FormationFormulation: Cream

Trifarotene

We don't sell this generic-version medication.

Select the quantity to see the price.

  *  
delivery

* This price includes a dispensing fee, medical review fee, and packing fee.

delivery

Shipped and delivered directly to your doorstep

Aklief Cream contains the active ingredient trifarotene. It is a prescription topical retinoid used to treat acne vulgaris on the face and trunk, including the chest, shoulders, and back.

In the United States, Aklief Cream is approved for adults and children aged 9 years and older. Age approvals may differ by country, so follow the product information and instructions provided by your healthcare provider.

Understanding Acne Vulgaris

Acne vulgaris is a common skin condition that develops when hair follicles become blocked with excess oil and dead skin cells.

Blocked pores may lead to several types of acne lesions, including:

  • Blackheads
  • Whiteheads
  • Small red bumps
  • Pimples containing pus
  • Inflamed or tender spots

Acne commonly affects the face, but it can also appear on the chest, shoulders, and back. Body acne may be difficult to treat because it can cover larger areas and may be affected by sweat, tight clothing, and friction.

Facial and Body Acne Treatment

Aklief Cream can be applied to acne-affected areas of the face and trunk.

The trunk includes areas such as the:

  • Chest
  • Shoulders
  • Upper back
  • Lower back

Using one medication for both facial and body acne may make treatment easier. However, apply it only to the areas recommended by your healthcare provider.

Avoid applying Aklief Cream to healthy skin that does not require treatment unless instructed otherwise.

How Aklief Cream Works

Aklief Cream belongs to a group of medications called topical retinoids. Retinoids are chemically related to vitamin A.

Trifarotene attaches mainly to retinoic acid receptor gamma, a receptor commonly found in the skin. By activating this receptor, the medication helps regulate the growth and development of skin cells.

This action may help prevent dead skin cells from building up and blocking the pores.

Prevention of Blocked Pores

Normal skin cells are continually produced and shed. In acne-prone skin, these cells may collect inside the hair follicles instead of leaving the skin normally.

The collected cells can mix with oil and form a blockage called a comedone. A comedone may appear as a blackhead or whitehead.

Aklief Cream helps normalise the way skin cells are produced and shed. This may:

  • Keep pores clearer
  • Reduce existing blackheads and whiteheads
  • Prevent new clogged pores from forming
  • Reduce the development of new acne lesions

Reduction of Inflammation

Acne is not only caused by clogged pores. Inflammation also contributes to redness, swelling, tenderness, and painful pimples.

Aklief Cream has anti-inflammatory activity that may help reduce inflamed acne lesions.

With regular treatment, the skin may develop fewer red bumps and pimples. However, results develop gradually and vary between patients.

Types of Acne Treated

Aklief Cream may help treat both non-inflammatory and inflammatory acne.

Non-inflammatory acne includes:

  • Blackheads
  • Whiteheads
  • Small clogged pores

Inflammatory acne includes:

  • Red bumps
  • Swollen pimples
  • Tender acne lesions
  • Pimples containing pus

Aklief Cream may not be enough on its own for severe acne with deep nodules, cysts, or extensive scarring. A healthcare provider may recommend additional treatment.

Expected Treatment Benefits

When used regularly, Aklief Cream may help:

  • Clear blocked pores
  • Reduce blackheads and whiteheads
  • Decrease red and inflamed pimples
  • Prevent new acne lesions
  • Improve facial acne
  • Improve acne on the chest, shoulders, and back
  • Lower the risk of marks and scars caused by repeated breakouts

Preventing new acne is an important part of treatment. Apply the medication to the entire acne-affected area rather than using it only as a spot treatment, unless your healthcare provider gives different instructions.

Gradual Improvement

Aklief Cream does not usually clear acne immediately.

Some people may notice early improvement after several weeks, but more meaningful results often require regular treatment over a longer period. Continue using the medication as prescribed, even when changes are gradual.

Your healthcare provider may assess your skin after several weeks or months to determine how well the treatment is working.

Early Skin Irritation

Skin irritation is common when starting a topical retinoid.

Possible reactions include:

  • Dryness
  • Redness
  • Peeling
  • Burning
  • Stinging
  • Itching

These effects are often most noticeable during the first few weeks of treatment and may improve as the skin adjusts.

Applying more cream will not clear acne faster. It may only increase irritation.

Temporary Worsening of Acne

Some people notice that their acne appears to worsen when treatment begins. This may happen as blocked pores already forming beneath the skin become more visible.

Continue treatment unless the irritation or worsening is severe. Contact your healthcare provider if you develop significant pain, swelling, blistering, crusting, or severe peeling.

Supportive Skin Care

A gentle skincare routine can help reduce irritation during treatment.

Use a mild cleanser and a non-comedogenic moisturiser. Non-comedogenic products are less likely to block the pores.

Avoid harsh or drying products unless your healthcare provider recommends them. These may include:

  • Abrasive scrubs
  • Strong exfoliating acids
  • Alcohol-based toners
  • Medicated or drying cleansers
  • Waxing products
  • Other topical retinoids

Ask your healthcare provider before combining Aklief Cream with other acne treatments.

Sun Sensitivity

Aklief Cream may make the treated skin more sensitive to sunlight.

Protect your skin by:

  • Using a broad-spectrum sunscreen
  • Wearing protective clothing
  • Seeking shade when possible
  • Avoiding tanning beds and sunlamps
  • Limiting unnecessary sun exposure

Wind and cold weather may also increase dryness and irritation.

Role in a Complete Acne Plan

Aklief Cream may be used alone or with other acne treatments. Depending on the type and severity of acne, a healthcare provider may recommend additional medications, such as benzoyl peroxide, topical antibiotics, or oral treatments.

A complete acne plan may also include gentle cleansing, moisturising, sun protection, and avoiding the picking or squeezing of pimples.

Picking acne can increase inflammation and raise the risk of infection, dark marks, and permanent scarring.

Individualised Treatment

A healthcare provider will decide whether Aklief Cream is appropriate based on:

  • The patient’s age
  • The type of acne
  • The severity of the breakouts
  • The areas of the body affected
  • Skin sensitivity
  • Previous acne treatments
  • Other skincare products or medications
  • Pregnancy or plans to become pregnant

The treatment schedule may be adjusted if the skin becomes excessively irritated.

Role in Long-Term Acne Control

Aklief Cream helps control acne but does not permanently cure the condition. Acne may return if treatment is stopped too early.

Once the skin improves, a healthcare provider may recommend continued treatment to prevent new pores from becoming blocked.

Use Aklief Cream consistently and attend follow-up appointments so your healthcare provider can assess your progress and manage irritation.

Use Aklief Cream exactly as directed by your healthcare provider. It is usually applied once daily in the evening.

Applying more cream or using it more often will not clear acne faster. It may increase dryness, redness, peeling, burning, or irritation.

Preparing the Skin

Before applying Aklief Cream:

  • Wash the treatment area gently with a mild or soap-free cleanser.
  • Rinse the skin well.
  • Pat the area dry with a soft towel.
  • Allow the skin to dry fully before applying the cream.

Avoid scrubbing the skin, as this may increase irritation.

Applying Aklief Cream

Apply a thin layer to the entire acne-affected area, not only to individual pimples.

Keep the cream away from the:

  • Eyes
  • Eyelids
  • Lips
  • Corners of the nose
  • Inside of the nostrils
  • Mouth
  • Broken, sunburned, or irritated skin

Wash your hands after applying the medication unless your hands are being treated.

Recommended Amount for the Face

Use one pump to cover the entire face.

Spread the cream in a thin, even layer over acne-prone areas. Avoid applying extra cream to areas with more pimples.

Recommended Amount for the Upper Body

Use two pumps to cover the upper back, shoulders, and chest.

If acne also affects the middle or lower back, one additional pump may be used.

Use only enough cream to create a thin layer over the affected skin.

Sun Protection

Aklief Cream may make the skin more sensitive to sunlight.

Use a broad-spectrum sunscreen every day. The product information recommends at least SPF 15, although a higher SPF may provide better protection when used correctly.

You should also:

  • Wear protective clothing
  • Use a hat when outdoors
  • Seek shade when possible
  • Avoid tanning beds and sunlamps
  • Limit unnecessary sun exposure

Wind and cold weather may also worsen dryness and irritation.

Moisturising the Skin

A gentle, non-comedogenic moisturiser may help reduce dryness and irritation.

You may apply moisturiser before or after Aklief Cream, depending on the instructions from your healthcare provider. Non-comedogenic products are less likely to block the pores.

Missed Application

If you forget to apply Aklief Cream, skip the missed application and use it at your usual time the following evening.

Do not apply extra cream to make up for the missed dose.

Managing Skin Irritation

Mild redness, dryness, peeling, burning, or stinging may occur during the first few weeks of treatment.

Your healthcare provider may recommend:

  • Using a moisturiser more often
  • Applying the cream less frequently
  • Temporarily pausing treatment
  • Avoiding other irritating skincare products

Contact your healthcare provider if the irritation becomes severe or if you develop swelling, blistering, crusting, or significant pain.

Important Application Reminders

Do not apply Aklief Cream more than once daily unless your healthcare provider specifically tells you to do so.

Avoid waxing treated skin and use caution with scrubs, exfoliating acids, alcohol-based products, or other retinoids.

Continue treatment as prescribed, even if improvement is gradual.

Common Side Effects of Aklief Cream (Trifarotene):

  • Irritation at application site
  • Sunburn
  • Skin itching
  • Dryness
  • Scaling
  • Itching
  • Mild stinging/burning

Serious Side Effects of Aklief Cream (Trifarotene):

  • Changes in skin color
  • Dry skin
  • Pain at application site
  • Skin blisters or sores
  • Skin rash
  • Skin redness
  • Swelling
  • Worsening of acne

Aklief Cream (Trifarotene) is available in the following forms and strength:

Aklief Cream: Cream

  • 0.005%

Pregnancy and Breastfeeding

Tell your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.

Aklief Cream is a topical retinoid and is generally avoided during pregnancy because retinoids may harm an unborn baby. Stop using it and contact your healthcare provider if you become pregnant during treatment.

It is not known whether trifarotene passes into breast milk. If you are breastfeeding, your healthcare provider will help you weigh the possible benefits and risks.

Do not apply Aklief Cream to the nipple or surrounding breast area. This helps prevent the baby from coming into direct contact with the medication.

Other Retinoid Products

Do not use Aklief Cream with another topical retinoid unless your healthcare provider specifically recommends it.

Combining retinoids or similar acne treatments may cause severe dryness, redness, peeling, burning, or skin irritation.

Check with your healthcare provider before using products that contain:

  • Adapalene
  • Tazarotene
  • Tretinoin
  • Retinol
  • Strong exfoliating acids
  • Benzoyl peroxide
  • Medicated acne ingredients

Some products may still be used together under medical guidance, but the timing or frequency may need to be adjusted.

Skin Irritation

Aklief Cream may cause skin irritation, especially during the first few weeks of treatment.

Possible symptoms include:

  • Dryness
  • Redness
  • Peeling
  • Itching
  • Burning
  • Stinging

Mild irritation often improves as the skin adjusts. Using more cream or applying it more often will not clear acne faster and may make irritation worse.

Your healthcare provider may recommend using a moisturiser, applying the cream less often, or temporarily pausing treatment.

Contact your healthcare provider if you develop severe pain, swelling, blistering, crusting, or intense peeling.

Gentle Skin Care

Use a mild or soap-free cleanser while using Aklief Cream.

Avoid products that may dry or irritate the skin, including:

  • Abrasive scrubs
  • Harsh soaps
  • Alcohol-based toners
  • Chemical peels
  • Waxing products
  • Strong exfoliants
  • Other drying acne treatments

Use gentle, non-comedogenic skincare products that are less likely to block the pores.

Sun Sensitivity

Aklief Cream may make your skin more sensitive to sunlight.

Avoid unnecessary or prolonged exposure to:

  • Direct sunlight
  • Tanning beds
  • Sunlamps
  • Other artificial ultraviolet light

Use a broad-spectrum sunscreen every day and wear protective clothing when outdoors. Wind and cold weather may also increase dryness and irritation.

Do not apply Aklief Cream to sunburned skin. Wait until the skin has fully healed.

Damaged or Irritated Skin

Do not apply Aklief Cream to skin that is:

  • Cut or scraped
  • Sunburned
  • Affected by eczema
  • Severely irritated
  • Broken or infected

Applying the medication to damaged skin may increase burning, pain, and absorption.

Medication and Product Interactions

Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, supplements, and skincare treatments you use.

Although trifarotene has limited absorption into the bloodstream, other topical products can increase irritation when applied to the same areas.

Do not start a new acne medication or strong skincare product without checking with your healthcare provider.

Proper Storage

Store Aklief Cream at room temperature, away from excessive heat and moisture.

Keep the tube or pump container tightly closed when it is not being used. Do not freeze the medication.

Keep Aklief Cream out of the reach of children and pets. Do not use it after the expiry date printed on the packaging.

How Does Aklief Cream Work?

Aklief Cream contains trifarotene, a topical retinoid related to vitamin A. It helps regulate how skin cells grow and shed. This prevents dead skin cells from building up inside the pores and reduces the formation of blackheads, whiteheads, and pimples. Aklief Cream also helps reduce inflammation, redness, and swelling caused by acne.

How Do I Use Aklief Cream?

Use Aklief Cream exactly as directed by your healthcare provider. It is usually applied once daily in the evening. Clean the affected skin gently, pat it dry, and apply a thin layer over the entire acne-prone area. Avoid the eyes, lips, corners of the nose, and broken or irritated skin. Wash your hands after applying the cream. Do not use more than prescribed. Applying extra cream will not clear acne faster and may cause more irritation.

How Long Does Aklief Cream Take to Work?

Some people may notice early improvement within two weeks. However, results vary, and more noticeable improvement may take several weeks. Clinical studies commonly assessed treatment after about 12 weeks of daily use. Continue using Aklief Cream as prescribed, even if your acne does not improve immediately. Contact your healthcare provider if your acne becomes worse or does not improve after several weeks.

Can Aklief Cream Be Used With Other Acne Medications?

Do not combine Aklief Cream with another retinoid unless your healthcare provider tells you to do so. Using several retinoids or irritating acne products together may cause severe dryness, peeling, redness, or burning. Tell your healthcare provider about all acne medications and skincare products you use. This includes benzoyl peroxide, salicylic acid, exfoliating acids, retinol, adapalene, tretinoin, and medicated cleansers. Your healthcare provider may recommend using certain products at different times of the day to reduce irritation.

How Should Aklief Cream Be Stored?

Store Aklief Cream at room temperature, away from excessive heat and moisture. Keep the container tightly closed when it is not in use. Do not freeze the cream. Keep it out of the reach of children and pets. Do not use the medication after the expiry date shown on the packaging.

REVIEWS

Additional Information Book
Generic name:

Trifarotene

Formulation:

Cream

Strength(s):

0.005%

Quantities Available:

60 grams, 120 grams

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Aklief Cream can I order at once from a Canadian pharmacy?

When ordering Aklief Cream (trifarotene) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Aklief Cream is typically applied once daily in the evening to the affected areas. The amount used per application can vary depending on the extent of the area being treated, but a common recommendation is to use a pea-sized amount for each area of the face (e.g., forehead, each cheek, chin, etc.).

Assuming you use approximately one gram per application, then for a 90-day supply, you would need 90 grams of Aklief Cream (1 gram per day x 90 days).

Do you sell trifarotene?

No, we do not sell trifarotene directly. However, you can still enjoy low prices on Aklief Cream, which contains trifarotene as an active ingredient. To purchase Aklief Cream from our website, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication. You can conveniently submit your prescription by mail, fax, or upload it through your online account during the ordering process.

Do you offer shipping of Aklief Cream (trifarotene) to the United States?

Yes, we ship Aklief Cream (trifarotene) to both the United States and Puerto Rico.

Discover Our Users' Stories!

Watch how Online Pharmacies Canada is helping customers save money on their medications.

Online Pharmacies Canada Customer Testimonial #4
Online Pharmacies Canada Customer Testimonial #1
Online Pharmacies Canada - Customer Testimonial #2

Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Aklief Cream (Trifarotene). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Aklief Cream (Trifarotene).