Veregen (Sinecatechins)

Indications

Veregen is a topical medication used to treat external genital and perianal warts caused by the human papillomavirus (HPV). It contains Sinecatechins, which are derived from green tea leaves and have antiviral and immunomodulatory properties. Veregen works by stimulating the immune system to attack the wart cells and reducing the number of HPV viral particles in the affected area.

While Veregen may help the infection clear faster, it does not cure warts. New warts may develop during or after treatment, and it does not prevent the spread of warts through sexual contact. Furthermore, using Veregen may weaken condoms and diaphragms. It is recommended to have a conversation with your doctor about safe sex practices.

Uses and Dosage

Veregen ointment is used to treat genital and anal warts in adults. Apply the ointment to all warts as prescribed, usually 3 times a day or as directed by your doctor. Here are the general instructions on how to use Veregen Ointment:

1. Wash your hands before and after applying the medication.
2. Clean the affected area with mild soap and water, and pat dry with a clean towel.
3. Apply a small amount of Veregen ointment (about a 0.5 cm strand for each wart) to each wart and the surrounding area.
4. Rub the ointment into the skin until it is completely absorbed.
5. Do not cover the treated area with a bandage or other covering.
6. Wash your hands after applying the medication.

It may take several weeks or months for the warts to clear up with Veregen treatment. Consult with your doctor if your symptoms do not improve or get worse. Veregen should be used only for external warts and not for internal warts or warts in the urethra, rectum, or vagina.

Side effect

Common Side Effects of Veregen (Sinecatechins):

• Burning
• Hardening of skin
• Itching
• Pain or discomfort
• Skin redness
• Skin ulcers
• Small blisters
• Swelling

Serious Side Effects of Veregen (Sinecatechins):

• Bleeding
• Discharge
• Lymph node infection causing swelling around the application site
• Peeling skin
• Rash
• Scar
• Skin irritation

Form and strength

Veregen (Sinecatechins) is available in the following forms and strength:

Veregen: Ointment

• 10%

Caution

• Veregen is for external use only and should not be applied to internal genital warts, vaginal warts, cervical warts, anal warts, or intra-anal warts.
• Veregen may cause skin irritation, including redness, itching, burning, pain, and ulceration. Inform your healthcare provider if you experience severe skin reactions.
• Veregen is not recommended during pregnancy or breastfeeding. If you are pregnant or breastfeeding, consult your healthcare provider before using Veregen.
• Veregen may interact with other drugs or products you are using, including prescription and over-the-counter medications, vitamins, and herbal supplements. Inform your healthcare provider and pharmacist of all the products you are using before starting Veregen.
• Veregen has not been evaluated for the treatment of urethral, intra-vaginal, cervical, rectal, or intra-anal human papillomavirus (HPV) infections, and should not be used to treat these conditions.
• The safety and effectiveness of Veregen in children under the age of 18 have not been established.
• Veregen may decrease the effectiveness of latex condoms and diaphragms for up to 72 hours after application. Therefore, it is recommended to avoid sexual activity or use an alternative form of barrier contraception during this time.
• Veregen may cause mild to moderate pain, itching, or burning during sexual intercourse if it is still present in the treatment area. Therefore, it is recommended to wait at least 10 minutes after applying Veregen before engaging in sexual activity.
• Veregen may cause an increase in INR (international normalized ratio) levels in patients using anticoagulant therapy. Inform your healthcare provider if you are using anticoagulants before starting Veregen.
• Veregen may not be suitable for people with weakened immune systems, as the safety and effectiveness of the medication have not been established in these populations.
• Veregen may stain clothing and other textiles, avoid contact with clothing immediately after applying.
• Veregen should be used only by the person it was prescribed for, do not share it with others, especially someone with the same symptoms.
• Veregen should be stored at room temperature, away from moisture and heat. Do not freeze the medication.

Frequently Asked Questions (FAQ)

How long should I use Veregen (sinecatechins)?

You should use Veregen (sinecatechins) until your warts are clear or otherwise instructed by your provider, but not longer than 4 months (16 weeks) months).

When do you stop using Veregen?

Treatment with Veregen Ointment should be continued until complete clearance of all warts, however no longer than 16 weeks. If your warts do not go away, or if they come back after treatment call your doctor.

Is Veregen suitable for children?

The safety and effectiveness of Veregen in children under the age of 18 has not been established, so it is not recommended for use in this population.

How long does it take for Veregen to work?

Veregen treatment can take up to 16 weeks, and improvements may be seen as early as 4 weeks. Continue using Veregen as directed, even if you do not see immediate improvement.

Can Veregen be used during pregnancy?

The safety of Veregen during pregnancy has not been established, so it should only be used if the potential benefits outweigh the potential risks.

Resources

• https://www.everydayhealth.com/drugs/sinecatechins-topical
• https://www.drugs.com/veregen.html
• https://www.goodrx.com/veregen/what-is
• https://www.webmd.com/drugs/2/drug-149848/veregen-topical/details
• https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=2c1cd745-79ab-487d-b759-995794cedb92
• https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/021902s002lbl.pdf