Indications
Accupril is a prescription drug used to treat high blood pressure, and congestive heart failure, and prevent kidney problems in people with diabetes. It contains an active ingredient called Quinapril. Quinapril belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors. It works by making the blood vessels wider, allowing more blood and oxygen to flow through them more easily.
By lowering high blood pressure, Accupril helps prevent strokes, heart attacks, and kidney problems. Quinapril can be used to treat kidneys, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
Uses and Dosage
Accupril (Quinapril) is prescribed in tablet form to be taken orally, with or without food, as per the doctor's instructions, typically once or twice a day. The medication's effectiveness may be compromised if taken with a high-fat meal. To minimize adverse events, physicians may start with a lower dose and gradually increase it. Patients should carefully adhere to their doctor's guidelines.
The recommended initial dosage of Accupril (Quinapril) may vary depending on the patient's medical condition.
- In patients not taking diuretics, the recommended initial dose is typically 10 or 20 mg once daily. The dosage may be adjusted based on blood pressure response.
- High blood pressure: Most people start with 10 to 20 mg by mouth once daily. Your doctor can raise your dose every few weeks until your blood pressure is under control. The maximum dose for lowering your blood pressure is 80 mg per day.
- Heart failure: Most people start with 5 mg by mouth twice daily. Your doctor can raise your dose every few weeks. The usual dosage range is 10 to 20 mg by mouth twice daily.
Side Effect
Common Side Effects of Accupril (Quinapril):
- Dizziness
- Dry cough
- Headache
- Lightheadedness
- Nausea
- Stomach discomfort
- Tiredness or fatigue
- Vomiting
Serious Side Effects of Accupril (Quinapril):
- Bleeding gums
- Changes in urine output
- Cold or clammy skin
- Dark urine
- Enlarged pupils
- Fainting
- Fast or slow heartbeat
- High potassium level in the blood or hyperkalemia (muscle weakness, slow heartbeat)
- Increased sensitivity of the skin or eyes to sunlight
- Loss of appetite
- Persistent nausea and vomiting
- Severe stomach pain
- Stiff or sore neck
- Yellowish eyes or skin
Form and Strength
Accupril (Quinapril) is available in the following forms and strength:
Accupril: Tablet
- 5 mg
- 10 mg
- 40 mg
Quinapril: Tablet
- 5 mg
- 10 mg
- 20 mg
Caution
- Accupril may cause low blood pressure, angioedema (a rare allergic reaction with swelling of the face, lips, tongue, or throat), or exacerbate kidney or liver disease.
- Increased risk of hypotension (low blood pressure), especially in patients who are dehydrated or taking antihypertensive medications.
- Patients should be cautioned about the risk of dizziness or lightheadedness, especially when rising from a sitting or lying position, due to the potential for hypotension.
- Patients with a history of liver disease should be monitored closely for signs of liver damage while taking quinapril.
- Possibility of increased risk of hyperkalemia (high potassium levels), especially in patients with kidney problems.
- Potential for interactions with other medications, such as diuretics, potassium supplements, and nonsteroidal anti-inflammatory drugs (NSAIDs).
- Quinapril should be used cautiously in patients with renal impairment, as it can exacerbate kidney function and cause a decrease in urine output.
- Quinapril should not be used in patients with a history of angioedema or hereditary angioedema.
- Quinapril should not be used in pediatric patients under the age of 6 years old.
- Risk of angioedema, a rare but serious allergic reaction that can cause swelling of the face, lips, tongue, or throat.
- Risk of fetal toxicity if taken during pregnancy.
- Some caution is advised when taking Accupril, as it can interact with other medications and may not be suitable for patients with certain medical conditions.
Frequently Asked Questions (FAQ)
How long will it take for Accupril to work?
It may take around two weeks before you feel the full effects of this treatment.
Can this medication be cut or crushed?
You may split this tablet with the supervision of a pharmacist.
Does this medication cause erectile dysfunction?
Erectile dysfunction has not been directly linked to quinapril.
Can I take Quinapril during pregnancy or while breastfeeding?
Do not use Quinapril during pregnancy or while breastfeeding. Women who are pregnant or planning to become pregnant should talk to their healthcare provider about alternative treatment options.
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