Prescription Required
Formulation: Transdermal Patches
(Brand Option)
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Prescription Required
Formulation: Transdermal Patches
(Generic Alternative)
Select the prescribed dosage
Select the quantity to see the price.
* This price includes a dispensing fee, medical review fee, and packing fee.
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Vivelle-DOT contains estradiol, a form of estrogen. It is a prescription hormone therapy delivered through a skin patch.
Vivelle-DOT may be used to relieve moderate to severe symptoms of menopause, especially:
These symptoms can happen when estrogen levels decrease during and after menopause.
Vivelle-DOT may also be used as estrogen replacement therapy in people who do not produce enough estrogen, including some people whose ovaries do not function normally or who have had their ovaries removed.
Vivelle-DOT releases estradiol through the skin and into the bloodstream.
Estradiol replaces some of the estrogen that the body no longer produces in sufficient amounts.
This can help reduce hot flashes and other symptoms linked to low estrogen levels.
If vaginal symptoms are your only concern, your healthcare provider may consider a local vaginal estrogen treatment instead of a systemic estrogen patch.
If you still have a uterus, your healthcare provider may also prescribe a progestogen along with Vivelle-DOT to help reduce the risk of abnormal thickening of the uterine lining.
Your healthcare provider will choose the lowest effective dose for the shortest appropriate treatment period based on your symptoms and health history.
Vivelle-DOT is a skin patch that delivers estradiol through the skin.
Apply a new patch twice a week, on the same two days each week. This usually means changing the patch every 3 to 4 days.
Apply Vivelle-DOT to a clean, dry area of skin on the lower abdomen or buttocks.
Do not apply the patch:
Use a different application site each time. Do not apply a new patch to the same area for at least 1 week.
Before applying the patch, make sure your skin is:
These steps help the patch stick properly.
Remove the patch from its protective pouch and peel away the protective liner.
Avoid touching the sticky side more than necessary.
Place the adhesive side directly onto your skin and press it firmly in place with the palm of your hand for about 10 seconds.
Make sure the edges are sticking securely.
Remove the old patch before applying a new one.
Follow the same twice-weekly schedule every week, such as Monday and Thursday or Tuesday and Friday.
Try to use different areas of skin each time to reduce irritation.
If the patch falls off, you may try to reapply it.
If it no longer sticks properly, apply a new patch to a different area.
Continue with your original patch-change schedule rather than starting a new schedule.
If you forget to change your Vivelle-DOT patch, apply a new patch as soon as you remember.
Then continue with your usual twice-weekly schedule.
Do not apply extra patches to make up for a missed change.
Use only the number of patches prescribed by your healthcare provider.
Do not change the dose or stop treatment without speaking with your healthcare provider.
Your healthcare provider may periodically review your symptoms and determine whether you still need estrogen treatment.
Vivelle-DOT (Estradiol Hemihydrate) is available in the following forms and strength:
Vivelle-DOT contains estrogen, which can increase the risk of serious blood clots, stroke, and heart attack.
Do not use Vivelle-DOT if you currently have, or have a history of:
Seek emergency medical attention if you develop sudden chest pain, shortness of breath, weakness or numbness on one side of the body, trouble speaking, or severe leg pain or swelling.
Do not use Vivelle-DOT if you have breast cancer, a history of breast cancer, or another known estrogen-dependent cancer.
Long-term estrogen therapy may affect the risk of certain cancers, depending on whether estrogen is used alone or together with a progestogen.
Your healthcare provider will consider your personal and family medical history before recommending treatment.
If you still have a uterus, using estrogen without a progestogen can increase the risk of abnormal thickening of the uterine lining and endometrial cancer.
Your healthcare provider may prescribe a progestogen along with Vivelle-DOT to help reduce this risk.
Tell your healthcare provider if you develop unusual, unexpected, or persistent vaginal bleeding or spotting.
Vivelle-DOT should not be started if you have unexplained vaginal bleeding until the cause has been evaluated.
Do not use Vivelle-DOT if you have liver impairment or active liver disease.
The liver helps process estrogen, and impaired liver function can affect how the medication is handled by your body.
Estrogen therapy can increase the risk of gallbladder disease.
Contact your healthcare provider if you develop severe pain in the upper right side of your abdomen, nausea, vomiting, or yellowing of the skin or eyes.
Tell your healthcare provider if you have:
These conditions can increase the overall risk of heart and blood vessel problems during estrogen treatment.
Smoking increases the risk of cardiovascular disease and blood clots.
Tell your healthcare provider if you smoke or use nicotine products, especially if you have other risk factors for blood clots, stroke, or heart disease.
Follow your healthcare provider’s recommendations for breast examinations and mammograms.
Contact your healthcare provider if you notice:
Vivelle-DOT is not intended for use during pregnancy.
Tell your healthcare provider if you become pregnant or think you may be pregnant while using the patch.
Tell your healthcare provider if you are breastfeeding.
Estrogen can pass into breast milk and may also reduce milk production, particularly when breastfeeding is being established.
Your healthcare provider can help determine whether Vivelle-DOT is appropriate.
Common side effects may include:
Contact your healthcare provider if side effects are severe or persistent.
Do not use another estrogen-containing medication or hormone product along with Vivelle-DOT unless your healthcare provider recommends it.
Using additional estrogen may increase your total estrogen exposure and raise the risk of side effects.
Your healthcare provider should periodically review whether you still need Vivelle-DOT and whether your dose remains appropriate.
Use the lowest effective dose for the shortest appropriate length of time based on your symptoms and treatment goals.
No. Vivelle-DOT contains estradiol only, which is a form of estrogen. If you still have a uterus, your healthcare provider may also prescribe a progestogen to help protect the lining of the uterus and reduce the risk of endometrial cancer.
Vivelle-DOT is not specifically approved as a fertility medication. However, estradiol patches may sometimes be used off-label as part of a fertility treatment plan to help prepare or support the uterine lining. If Vivelle-DOT is being used during fertility treatment, follow the exact schedule provided by your fertility specialist.
Vivelle-DOT contains estradiol, which is chemically the same type of estrogen that is naturally produced by the ovaries. The patch replaces estrogen when the body is no longer producing enough of it.
How long you use Vivelle-DOT depends on why it was prescribed, your symptoms, your health history, and whether you still have a uterus. If you do not have a uterus, Vivelle-DOT may be used continuously. If you still have a uterus, it may be used on a cyclic schedule, such as 3 weeks on treatment followed by 1 week off, depending on your healthcare provider’s instructions. Your healthcare provider should periodically review whether you still need estrogen therapy. Use the lowest effective dose for the shortest appropriate length of time based on your treatment goals and risks.
| Generic name: | Estradiol Hemihydrate |
|---|---|
| Formulation: | Transdermal Patches |
| Strength(s): | 25mcg, 37.5mcg, 50mcg, 75mcg, 100mcg |
| Quantities Available: | 8, 16, 24 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Vivelle-DOT (estradiol hemihydrate) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Vivelle-DOT patches are available in various strengths, including 25 mcg, 37.5 mcg, 50 mcg, 75 mcg, and 100 mcg of estradiol per day. The patches are usually replaced twice a week. For a 90-day supply, you would typically order 24 patches (12 weeks x 2 patches per week).
No, we do not sell estradiol hemihydrate on our website. However, you can still enjoy low prices on Vivelle-DOT, which contains estradiol hemihydrate as an active ingredient. To purchase Vivelle-DOT, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You have the option to submit your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Vivelle DOT (estradiol hemihydrate) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Vivelle DOT (Estradiol Hemihydrate). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Vivelle DOT (Estradiol Hemihydrate).
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