Prescription Required
Formulation: Capsule
Prescription Required
Formulation: Capsule
(Generic Alternative)
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Sustiva contains the active ingredient efavirenz. It is a prescription antiviral medication used as part of combination treatment for HIV.
Sustiva is used with other antiretroviral medications to treat human immunodeficiency virus (HIV) infection.
HIV attacks the immune system, especially CD4 cells, which help the body fight infections. Without treatment, HIV can weaken the immune system and increase the risk of serious infections and other health problems.
Sustiva helps reduce the amount of HIV in the blood, also known as the viral load.
Sustiva should not be used by itself to treat HIV.
It is prescribed as part of a combination antiretroviral therapy regimen. Using several HIV medications together helps control the virus more effectively and reduces the risk of HIV becoming resistant to treatment.
Sustiva may be used to treat HIV in adults and certain pediatric patients.
For children, the dose is based on factors such as body weight, age, and the treatment regimen.
A healthcare provider will determine whether Sustiva is appropriate and choose the correct dose.
Sustiva belongs to a class of HIV medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs).
HIV uses an enzyme called reverse transcriptase to make copies of its genetic material after entering a human cell.
Efavirenz attaches directly to reverse transcriptase and blocks its activity. This makes it more difficult for HIV to make new copies of itself.
By reducing HIV replication, Sustiva can help:
The goal of HIV treatment is usually to reduce the viral load to an undetectable level and keep it suppressed.
Sustiva does not cure HIV.
Even when the viral load becomes undetectable, HIV remains in the body. Treatment must therefore be taken consistently as prescribed to keep the virus under control.
Missing doses or stopping treatment without medical guidance may allow HIV to multiply and increase the risk of drug resistance.
During treatment, your healthcare provider may order blood tests to monitor:
These tests help determine how well your HIV treatment is working and whether changes to your medication regimen are needed.
Sustiva is taken by mouth once daily on an empty stomach, preferably at bedtime.
Taking Sustiva with food can increase the amount of efavirenz in your bloodstream and may increase the risk of side effects, especially dizziness, drowsiness, abnormal dreams, or difficulty concentrating.
Taking it at bedtime may help make these nervous system side effects easier to tolerate.
For most adults:
Usual dose: 600 mg once daily.
The 600 mg dose is taken as one 600 mg capsule.
Sustiva must always be used together with other HIV medications. It should not be used by itself.
Take Sustiva without food.
A good routine is to take it at bedtime, at least a few hours after your evening meal.
Food, especially a high-fat meal, can increase efavirenz levels and may make side effects more noticeable.
For people who cannot swallow capsules whole, the capsule contents may be opened and mixed with a small amount of soft food.
The contents can be gently mixed with about 1 to 2 teaspoons of food such as:
After taking the mixture, add about 2 more teaspoons of food to the empty container, mix again, and swallow the remaining mixture so that the full dose is taken.
The mixture should be used within 30 minutes of preparation.
Do not eat any additional food for 2 hours after taking the capsule mixture.
For pediatric patients, the Sustiva dose is based mainly on body weight.
Children weighing less than 40 kg may require lower doses using the 50 mg or 200 mg capsules.
Children weighing 40 kg or more generally receive 600 mg once daily.
Your healthcare provider will calculate the correct dose based on your child’s weight and treatment plan.
Take Sustiva at about the same time every day.
Taking HIV medications consistently helps keep the amount of virus in the blood low and reduces the risk of the virus becoming resistant to treatment.
Do not skip doses, change your dose, or stop Sustiva or your other HIV medications unless your healthcare provider tells you to.
If you miss a dose of Sustiva, take it as soon as you remember.
If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule.
Do not take two doses at the same time or take extra Sustiva to make up for a missed dose.
Stopping Sustiva or other HIV medications, even for a short period, can allow HIV to multiply again.
This may increase your viral load and make the infection harder to treat if the virus develops resistance.
Always speak with your healthcare provider before changing or stopping your HIV treatment.
Sustiva (Efavirenz) is available in the following forms and strength:
Sustiva can cause changes in mood, thoughts, or behavior.
Serious psychiatric symptoms have been reported, including:
Tell your healthcare provider if you have a history of depression, other mental health conditions, or substance use problems.
Seek medical attention promptly if you develop severe depression, thoughts of self-harm, or major changes in your mood or behavior.
Sustiva commonly causes nervous system side effects, especially when treatment is first started.
These may include:
Dizziness
These symptoms often begin during the first few days of treatment and may improve within 2 to 4 weeks.
Taking Sustiva at bedtime may make these effects easier to tolerate.
Sustiva can cause dizziness, drowsiness, difficulty concentrating, or problems with coordination.
Until you know how the medication affects you, avoid driving, operating machinery, or doing other activities that require full alertness.
Alcohol or other medications that affect the nervous system may make these effects worse.
Sustiva can cause liver injury.
The risk may be greater if you already have liver disease, hepatitis B or C, or take other medications that affect the liver.
Your healthcare provider may check your liver function before and during treatment.
Contact your healthcare provider if you develop symptoms such as:
Efavirenz is generally not recommended in people with moderate or severe liver impairment.
Rash can occur while taking Sustiva.
Most rashes are mild and improve without stopping treatment. However, rare serious skin reactions, including Stevens-Johnson syndrome, can occur.
Seek immediate medical attention if you develop a severe rash along with:
Sustiva can interact with many medications because efavirenz affects liver enzymes that process other drugs.
Some interactions may increase side effects, while others may make Sustiva or another medication less effective.
Tell your healthcare provider about all:
This includes St. John’s wort, which may reduce efavirenz levels and increase the risk of HIV treatment failure.
Sustiva should always be used with other HIV medications.
Skipping doses, stopping treatment, or using Sustiva by itself can allow HIV to multiply and become resistant to treatment.
Take all of your HIV medications exactly as prescribed, and do not stop them without speaking with your healthcare provider.
Tell your healthcare provider if you are pregnant, think you may be pregnant, or plan to become pregnant.
Efavirenz has been associated with potential risks during pregnancy, so your healthcare provider will review the benefits and risks and determine the most appropriate HIV treatment.
Do not stop Sustiva or your other HIV medications on your own if you become pregnant. Maintaining effective HIV treatment is important for your health and for reducing the risk of HIV transmission to the baby.
Tell your healthcare provider if you are breastfeeding or planning to breastfeed.
Current prescribing information recommends against breastfeeding during efavirenz treatment. Your healthcare provider can discuss feeding options based on your HIV treatment, viral load, and current clinical guidance.
Kidney impairment is not one of the main safety concerns with efavirenz itself, and Sustiva is not primarily removed from the body through the kidneys.
However, many HIV treatment regimens include other medications that can affect kidney function.
Tell your healthcare provider if you have kidney disease so your complete HIV treatment regimen can be reviewed appropriately.
Seizures have been reported in people taking efavirenz.
Tell your healthcare provider if you have a history of seizures or take anticonvulsant medications.
Additional monitoring may be needed during treatment.
As HIV treatment begins to strengthen the immune system, it may start responding more strongly to infections that were already present in the body.
This is called immune reconstitution syndrome.
Symptoms depend on the underlying infection and may include fever, swollen lymph nodes, breathing problems, or worsening symptoms of an existing infection.
In some cases, autoimmune conditions may also appear after the immune system begins to recover.
Contact your healthcare provider if you develop new or worsening symptoms after starting HIV treatment.
Your healthcare provider may monitor your health during Sustiva treatment with tests such as:
Regular monitoring helps determine whether the treatment is controlling HIV effectively and whether any side effects need attention.
Sustiva should be taken on an empty stomach, preferably at bedtime. A simple approach is to avoid food for about 2 hours before taking Sustiva. After taking it, continue to avoid food for about 2 hours unless your healthcare provider gives you different instructions. Taking Sustiva with food, especially a high-fat meal, can increase efavirenz levels in the body and may increase side effects such as dizziness, drowsiness, or unusual dreams.
Weight gain is not one of the most common side effects of Sustiva. However, body weight can still change during HIV treatment for many reasons, including changes in overall health, diet, activity level, or other medications in the treatment regimen. If you notice significant or unexplained weight gain, speak with your healthcare provider.
Sustiva belongs to a class of HIV medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It works by blocking the HIV reverse transcriptase enzyme, which the virus needs to make copies of itself. Sustiva should not be used alone to treat HIV. It must be taken together with other antiretroviral medications as part of a complete HIV treatment regimen.
| Generic name: | Efavirenz |
|---|---|
| Formulation: | Capsule |
| Strength(s): | 600mg |
| Quantities Available: | 30, 90 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Sustiva (efavirenz) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Sustiva is commonly prescribed in dosages of 200 mg or 600 mg, taken once daily. For a 90-day supply at a dosage of 600 mg, this means you would order 90 tablets (90 days x 1 tablet per day).
Yes, we sell efavirenz on our website. You can enjoy low prices when you order through us. To purchase efavirenz, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You have the option to submit your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Sustiva (efavirenz) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Sustiva (Efavirenz). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Sustiva (Efavirenz).
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