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Cymbalta, also known as duloxetine HCl, is an oral medication prescribed for the treatment of major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain. Cymbalta treats depression, anxiety, diabetic peripheral neuropathy, fibromyalgia, and chronic muscle or bone pain.
Duloxetine Hydrochloride, the active ingredient in Cymbalta, belongs to a class of drugs known as Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs). SNRIs work by increasing the levels of two neurotransmitters, serotonin, and norepinephrine, which are responsible for communication between neurons in the brain and are involved in regulating mood.
Cymbalta has antidepressant, anxiolytic, and central pain inhibitory properties due to its ability to potentiate noradrenergic and serotonergic activity in the central nervous system. It is used to treat major depressive disorder in adults, general anxiety disorder in adults and children who are at least 7 years old, and nerve pain caused by diabetes (diabetic neuropathy) or chronic muscle or joint pain (such as low back pain and osteoarthritis pain) in adults.
Cymbalta should be taken orally in the form of a delayed-release capsule, either once or twice daily, with or without food, depending on the indication. It is available in 60 mg, 30 mg, and 20 mg capsule forms.
The dosing information provided here is for Duloxetine in oral capsule form. It is important to note that not all dosages and forms are listed here. The dosage, form, and frequency of administration of the medication will depend on individual factors such as age, weight, medical history, severity of condition, and other medications being taken.
Adult dosage (ages 18 years and older):
Child dosage (ages 0–17 years): Dosage for people younger than 18 years has not been established.
Adult dosage (ages 18–64 years):
Child dosage (ages 7–17 years):
Child dosage (ages 0–6 years): Dosage for people younger than 7 years has not been established.
Senior dosage (ages 65 years and older):
Adult dosage (ages 18–64 years):
Child dosage (ages 0–17 years): Dosage for people younger than 18 years has not been established.
Adult dosage (ages 18 years and older):
Child dosage (ages 13–17 years):
Child dosage (ages 0–12 years): Dosage for people younger than 13 years has not been established.
Adult dosage (ages 18 years and older):
Child dosage (ages 0–17 years): Dosage for people younger than 18 years has not been established.
Cymbalta and its Generic Alternatives Duloxetine come forms and strengths:
People will need to take Cymbalta every day for one to two weeks before they notice any improvement in depression or anxiety symptoms. It may take longer to improve pain symptoms.
With a half-life of 12 hours, it takes the body about two days to completely clear a dose of Cymbalta from the body, but this will vary from person to person.
If a dose is missed, take it as soon as it’s remembered. However, if it is nearly time for the next dose, skip the missed dose and take the next dose on schedule. Do not take extra medicine to make up for a missed dose.
Cymbalta is given cautiously in pregnant women, particularly in the third trimester. The risk of harming the fetus is small, but when given in the third trimester, there is a risk that the baby will be born with withdrawal symptoms or serotonin syndrome.
| Generic name: | Duloxetine, Duloxetine Hydrochloride |
|---|---|
| Formulation: | DR Capsule, Delayed Release Capsule, Delayed Release Capsule (Enteric Coated) |
| Strength(s): | 20mg, 30mg, 40mg, 60mg |
| Quantities Available: | 28, 50, 60, 84, 100, 168, 252 |
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Cymbalta (Duloxetine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Cymbalta (Duloxetine).
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