Farxiga (active ingredient: dapagliflozin) is a prescription medication used to help manage type 2 diabetes, heart failure, and chronic kidney disease (CKD). It belongs to a group of medications called sodium-glucose cotransporter 2 (SGLT2) inhibitors.
Farxiga works by helping the kidneys remove excess glucose (sugar) from the body through the urine. It also helps reduce strain on the heart and kidneys, providing benefits beyond blood sugar management.
Farxiga for Type 2 Diabetes
Farxiga is used to improve blood sugar control in adults and children 10 years of age and older with type 2 diabetes. It is most effective when used alongside a healthy diet and regular physical activity.
In addition to lowering blood sugar levels, Farxiga can help reduce the risk of hospitalization for heart failure in adults with type 2 diabetes who have cardiovascular disease or multiple cardiovascular risk factors.
Key Benefits for Type 2 Diabetes
- Helps lower blood sugar levels.
- Supports long-term diabetes management.
- Reduces the risk of hospitalization due to heart failure in eligible patients.
Farxiga for Heart Failure
Farxiga is approved to help treat certain types of heart failure, including heart failure with reduced ejection fraction (HFrEF). In this condition, the heart cannot pump blood as effectively as it should, which can lead to symptoms such as shortness of breath, tiredness, and fluid buildup.
Farxiga can help reduce the burden of heart failure and improve long-term outcomes.
Key Benefits for Heart Failure
- Helps lower the risk of cardiovascular death.
- Reduces hospitalizations related to heart failure.
- Decreases the need for urgent medical visits due to worsening heart failure.
Farxiga for Chronic Kidney Disease (CKD)
Farxiga is also used in adults with chronic kidney disease to help protect kidney function and slow disease progression.
By supporting kidney health, Farxiga can help reduce the risk of serious kidney-related complications and cardiovascular events.
Key Benefits for Chronic Kidney Disease
- Helps slow the decline of kidney function.
- Reduces the risk of end-stage kidney disease.
- Lowers the risk of cardiovascular death.
- Helps reduce the risk of hospitalization for heart failure.
How Farxiga Works
Farxiga works by blocking a protein called SGLT2 in the kidneys. This action prevents some glucose from being reabsorbed back into the bloodstream, allowing excess sugar to be removed from the body through the urine.
Farxiga also helps the body eliminate excess sodium. This effect can reduce pressure on the heart and kidneys, helping improve heart function, support kidney health, and reduce the risk of complications associated with cardiovascular and kidney disease.
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