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Prescription Required
Formulation: Capsule
Select the quantity to see the price.
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Temodar contains the active ingredient temozolomide. It is a prescription chemotherapy medication used to treat certain types of brain tumors.
Temodar is commonly used to treat newly diagnosed glioblastoma, an aggressive type of brain cancer.
For newly diagnosed glioblastoma, Temodar is usually given together with radiation therapy during the first phase of treatment.
After radiation is completed, Temodar may be continued on its own in treatment cycles, depending on the treatment plan recommended by the oncology team.
Temodar may also be used to treat certain malignant brain tumors that have returned or continued to grow after previous treatment.
The exact use of Temodar depends on the type of tumor, previous treatments, and the patient’s overall condition.
Temodar belongs to a group of chemotherapy medications called alkylating agents.
After Temodar enters the body, it is converted into an active form that damages the DNA inside cancer cells.
Cancer cells need to copy their DNA in order to grow and divide.
Temodar adds chemical groups to the DNA, which interferes with this process.
When the DNA damage becomes too severe, the cancer cell may no longer be able to divide normally and may eventually die.
Temozolomide is able to cross the blood-brain barrier, which allows the medication to reach the brain and act on tumor cells.
This makes it useful for treating certain cancers that develop in the brain.
Temodar may help slow tumor growth, reduce disease activity, and improve outcomes in some patients, but it does not cure every brain tumor.
Your oncology team will monitor your response to treatment using imaging tests, blood tests, symptoms, and other clinical information.
During treatment, your healthcare team may monitor:
Regular monitoring helps determine whether Temodar should be continued, adjusted, delayed, or stopped.
Temodar is taken by mouth as a capsule, usually once daily according to the treatment schedule prescribed by your oncology team.
Take each dose at about the same time every day. Taking Temodar on an empty stomach, often at bedtime, may help reduce nausea and vomiting.
Swallow the capsules whole with a full glass of water.
Do not:
If a capsule becomes damaged or opened, avoid contact with the powder inside and follow your healthcare provider’s instructions for safe handling.
If you vomit after taking a dose of Temodar, do not take another dose that day.
Wait and take your next dose at the regularly scheduled time.
Contact your healthcare provider if vomiting is severe or continues, as anti-nausea medication may be needed.
If you miss a dose of Temodar, contact your healthcare provider or oncology team for instructions.
Because Temodar is given on a specific treatment schedule, do not automatically take the missed dose later or double your next dose.
Your healthcare provider will tell you whether to take the missed dose, skip it, or adjust your treatment schedule.
The exact dose and length of treatment depend on the type of brain tumor being treated, your body size, blood test results, previous treatment, and how well you tolerate the medication.
Do not take more or less Temodar than prescribed, and do not change your treatment schedule unless your oncology team tells you to.
For newly diagnosed glioblastoma, Temodar is commonly given in two treatment phases.
During the first phase, Temodar is usually taken once daily for 42 days while receiving radiation therapy. In some situations, treatment may continue for up to 49 days depending on interruptions or the treatment plan.
After a break, Temodar may then be given in repeated treatment cycles.
During maintenance treatment, Temodar is usually taken once daily for 5 consecutive days, followed by 23 days without Temodar.
This creates a 28-day treatment cycle.
Your oncology team will determine how many cycles you should receive and whether your dose needs to be adjusted between cycles.
For some recurrent or progressive brain tumors, Temodar may also be given once daily for 5 days in a row, followed by 23 days without treatment.
The cycle may then be repeated if your blood counts and overall condition allow treatment to continue.
Temodar can lower blood cell counts, so your healthcare team will perform blood tests during treatment.
These tests help monitor:
Your next treatment cycle may be delayed or your dose may be changed if your blood counts are too low or you develop significant side effects.
Temodar treatment schedules can be complicated because treatment days and rest days alternate.
Use the treatment calendar provided by your oncology team and make sure you understand which days you should take Temodar.
If you are unsure whether you should take a dose, contact your healthcare provider or pharmacist before taking it.
Temodar (temozolomide) is available in the following forms and strengths:
Temodar can cause myelosuppression, which means the bone marrow produces fewer blood cells.
This can lead to:
Your healthcare provider will order regular blood tests before and during treatment to monitor your blood cell counts.
Contact your healthcare provider if you develop fever, unusual bruising, bleeding, or signs of infection.
Temodar can weaken the immune system by lowering lymphocyte levels.
This may increase the risk of serious infections, including Pneumocystis pneumonia (PCP).
People receiving Temodar together with radiation therapy for newly diagnosed glioblastoma are generally given medication to help prevent PCP during the combined treatment phase.
Serious liver injury, including rare cases of liver failure, has been reported with Temodar.
Your healthcare provider may check your liver function before treatment, during treatment, before later treatment cycles, and after your final dose.
Contact your healthcare provider if you develop yellowing of the skin or eyes, dark urine, severe tiredness, or persistent abdominal discomfort.
Tell your healthcare provider if you have kidney or liver disease before starting Temodar.
People with severe kidney or liver impairment may require closer monitoring because there is less information about the use of Temodar in these populations.
Your oncology team will determine whether any changes to your treatment plan are needed.
Temodar can harm a developing fetus.
Women who can become pregnant should use effective contraception while taking Temodar and for 6 months after the last dose.
Tell your healthcare provider immediately if you become pregnant during treatment.
Temozolomide may also damage sperm.
Men with partners who are pregnant or able to become pregnant should use condoms during treatment and for 3 months after the last dose.
Men are also advised not to donate semen during this period.
Breastfeeding is not recommended during treatment with Temodar because of the potential for serious side effects in a nursing infant.
Do not take Temodar if you have had a serious allergic reaction to temozolomide, dacarbazine, or any ingredient in the medication.
Seek immediate medical attention if you develop swelling of the face or throat, difficulty breathing, hives, or another severe allergic reaction.
Temodar can cause tiredness, dizziness, or drowsiness in some people.
Avoid driving, operating machinery, or doing other activities that require full alertness until you know how the medication affects you.
Nausea and vomiting are common side effects of Temodar.
Your healthcare provider may prescribe anti-nausea medication before or during treatment.
Taking Temodar on an empty stomach or at bedtime may also help reduce nausea for some people.
Seizures can occur in people receiving Temodar, although seizures may also be related to the underlying brain tumor.
Tell your healthcare provider if you have a history of seizures or epilepsy.
Seek medical attention if you experience a new seizure or if your seizures become more frequent or severe.
Temodar may increase the risk of developing certain secondary cancers.
Cases of myelodysplastic syndrome and secondary myeloid leukemia have been reported in people treated with temozolomide-containing regimens.
During treatment, your healthcare team may monitor:
Regular monitoring helps determine whether Temodar treatment should continue, be delayed, or have the dose adjusted.
The length of Temodar treatment depends on the type of brain tumor being treated, how well the cancer responds, your blood test results, and how well you tolerate treatment. For newly diagnosed glioblastoma, Temodar is commonly taken daily for 42 to 49 days with radiation therapy, followed by maintenance treatment given for 5 days during each 28-day cycle. The standard maintenance schedule generally includes 6 cycles, although your oncology team may adjust the plan based on your individual situation. Your dose is usually based on your body surface area, which is calculated using your height and weight.
Temodar should be taken consistently in relation to food. This means you should try to take it the same way each day, either with food or without food. Taking Temodar on an empty stomach or at bedtime may help reduce nausea and vomiting. There is not a standard requirement to avoid food for exactly 1 hour before and 2 hours after every dose. Follow the specific instructions provided by your oncology team.
If you miss a dose of Temodar, contact your healthcare provider or oncology team for instructions. Because Temodar is given according to a specific treatment schedule, do not automatically take the missed dose later or add it to your next dose. Do not take two doses at the same time to make up for a missed dose.
Temodar may sometimes be continued after the initial treatment phase, depending on the type of tumor, your response to treatment, blood cell counts, and side effects. For newly diagnosed glioblastoma, maintenance Temodar is normally given after the initial period of Temodar combined with radiation therapy. Your oncology team will determine how many treatment cycles are appropriate for you. Do not continue, stop, or extend Temodar treatment on your own. Your healthcare provider will decide whether ongoing treatment remains appropriate based on your response and overall health.
| Generic name: | Temozolomide |
|---|---|
| Formulation: | Capsule |
| Strength(s): | 100mg |
| Quantities Available: | 5 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Temodar (temozolomide) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Temodar is commonly prescribed in dosages of 100 mg, taken once daily (depending on the patient’s body surface area). For a 90-day supply, this means you would order 90 capsules (90 days x 1 capsule per day, adjusting based on your specific prescribed dosage).
No, we do not sell temozolomide directly, but you can still enjoy low prices on Temodar, which contains temozolomide as an active ingredient. You will need a valid prescription from your healthcare provider to purchase Temodar. We require this to dispense the medication safely and appropriately. You can mail, fax, or upload your prescription through your online account.
Yes, we ship Temodar (temozolomide) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Temodar (Temozolomide). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Temodar (Temozolomide).
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