Tecfidera is a delayed-release capsule taken by mouth twice daily.
It can be taken with or without food. However, taking Tecfidera with food may help reduce flushing, a common side effect.
Swallow the Capsule Whole
Swallow Tecfidera capsules whole and intact.
Do not:
- Crush the capsules
- Chew the capsules
- Open the capsules
- Sprinkle the capsule contents on food
The delayed-release formulation is designed to release the medication properly after it is swallowed.
Starting Dose
Starting dose: 120 mg twice daily for the first 7 days.
Maintenance Dose
After 7 days, the dose is increased to:
Maintenance dose: 240 mg twice daily.
Try to take your doses at approximately the same times each day to help maintain a consistent treatment schedule.
If You Have Trouble Tolerating the Maintenance Dose
If side effects make the 240 mg twice-daily dose difficult to tolerate, your healthcare provider may temporarily reduce the dose to 120 mg twice daily.
The recommended maintenance dose of 240 mg twice daily should generally be restarted within 4 weeks if tolerated.
If you are unable to return to the recommended maintenance dose, your healthcare provider may consider stopping Tecfidera.
Managing Flushing
Flushing may cause warmth, redness, itching, or a burning sensation.
Taking Tecfidera with food may help reduce how often flushing occurs or how severe it becomes.
Do not take aspirin specifically for flushing unless your healthcare provider recommends it, as aspirin may not be appropriate for everyone.
Take Tecfidera Regularly
Take Tecfidera exactly as prescribed, even when you are feeling well.
Tecfidera is used as a long-term disease-modifying treatment for multiple sclerosis, so taking it consistently is important for maintaining its effect.
Do not increase, decrease, or stop your dose without first speaking with your healthcare provider.
What to Do If You Miss a Dose
If you miss a dose, take it when you remember unless it is almost time for your next scheduled dose.
If your next dose is approaching, skip the missed dose and continue with your regular schedule.
Do not take two doses at the same time to make up for a missed dose.
Follow Your Healthcare Provider’s Instructions
Your healthcare provider may monitor blood tests and your overall response to Tecfidera during treatment.
Contact your healthcare provider if side effects become difficult to manage or if you develop new or worsening symptoms.
REVIEWS