Prescription Required
Formulation: Delayed Release Capsule
(Brand Option)
Select the prescribed dosage
Select the quantity to see the price.
Prescription Required
Formulation: Delayed Release Capsule
Select the quantity to see the price.
* This price includes a dispensing fee, medical review fee, and packing fee.
Shipped and delivered directly to your doorstep
Pertzye is a prescription medication used to treat exocrine pancreatic insufficiency (EPI), a condition in which the pancreas does not produce or release enough digestive enzymes to properly break down food.
It contains pancrelipase, a combination of three digestive enzymes: lipase, protease, and amylase. These enzymes help the body digest fats, proteins, and carbohydrates so that essential nutrients can be absorbed.
Pertzye belongs to a class of medications called pancreatic enzyme replacement therapies (PERT). It replaces digestive enzymes that the pancreas cannot supply in sufficient amounts.
Pertzye is available as delayed-release capsules and is approved for adults and children, including infants, with exocrine pancreatic insufficiency.
Pertzye helps improve food digestion and nutrient absorption in people with pancreatic enzyme deficiencies. It is commonly used for EPI associated with cystic fibrosis and other pancreatic conditions.Â
Pertzye is primarily prescribed to treat exocrine pancreatic insufficiency, a digestive condition caused by insufficient pancreatic enzyme production or delivery.
Normally, the pancreas releases digestive enzymes into the small intestine. These enzymes break down food into smaller components that the body can absorb and use for energy, growth, and tissue repair.
When the pancreas does not produce enough digestive enzymes, food may pass through the digestive system without being properly broken down.
This can cause digestive problems and poor nutrient absorption, also known as malabsorption.
Common symptoms of EPI include greasy or oily stools, frequent diarrhea, abdominal bloating, excessive gas, stomach discomfort, and unexplained weight loss.
Some patients may also develop nutritional deficiencies because their bodies cannot adequately absorb fats, proteins, and certain vitamins.
Pertzye provides replacement digestive enzymes that work in the small intestine to help break down food.
By improving digestion, Pertzye may help reduce digestive discomfort, improve stool consistency, and support better nutritional absorption.
Pertzye helps manage exocrine pancreatic insufficiency by replacing missing digestive enzymes, improving nutrient absorption, and reducing symptoms associated with poor digestion.
Pertzye is commonly prescribed for patients with cystic fibrosis who develop exocrine pancreatic insufficiency.
Cystic fibrosis is an inherited condition that affects the lungs, digestive system, and other organs.
The disease causes the body to produce unusually thick and sticky mucus.
In the pancreas, this mucus can block the small ducts responsible for delivering digestive enzymes into the intestine.
As a result, the enzymes may not reach food in sufficient amounts to support normal digestion.
Patients with cystic fibrosis-related pancreatic insufficiency may experience greasy stools, abdominal bloating, poor weight gain, and nutritional deficiencies.
Children may also experience difficulties with normal growth and development when nutrient absorption is inadequate.
Pertzye helps replace the missing enzymes, allowing the body to digest food more effectively.
When taken with meals and snacks as prescribed, it can help improve fat absorption and support adequate nutrition.
However, Pertzye does not treat the underlying genetic cause of cystic fibrosis or the respiratory symptoms associated with the condition.
Pertzye helps patients with cystic fibrosis-related pancreatic insufficiency digest food, absorb nutrients, and maintain better nutritional health.
Pertzye may also be prescribed for patients who develop exocrine pancreatic insufficiency due to chronic pancreatitis.
Chronic pancreatitis is a long-term inflammatory condition that gradually damages the pancreas.
Over time, repeated inflammation may cause scarring and reduce the pancreas’s ability to produce digestive enzymes.
When enzyme production becomes insufficient, patients may have difficulty digesting fats, proteins, and carbohydrates.
Symptoms may include abdominal discomfort, oily stools, diarrhea, bloating, and unintentional weight loss.
Poor fat absorption may also contribute to deficiencies in vitamins A, D, E, and K.
Pertzye supplies digestive enzymes to help compensate for the reduced function of the pancreas.
This may improve digestion, reduce symptoms of malabsorption, and help patients maintain a healthier nutritional status.
However, Pertzye does not reverse pancreatic damage or cure chronic pancreatitis.
Pertzye may help patients with chronic pancreatitis-related EPI improve digestion and nutrient absorption, but it does not repair existing pancreatic damage.
Pertzye may be prescribed for patients who develop exocrine pancreatic insufficiency as a result of pancreatic cancer.
Pancreatic cancer can interfere with normal digestive enzyme production or block the ducts that transport enzymes from the pancreas into the small intestine.
When digestive enzymes cannot reach food in sufficient amounts, patients may develop malabsorption.
Common symptoms include diarrhea, greasy stools, bloating, weight loss, and poor appetite.
These digestive problems may contribute to malnutrition, weakness, and reduced quality of life.
Pertzye provides replacement enzymes that help break down food and support better nutrient absorption.
Improved digestion may help patients obtain more nutrients from their meals and maintain their nutritional status.
Pertzye may also be prescribed to patients who develop EPI after pancreatic surgery, including procedures performed to treat pancreatic cancer.
However, the medication does not treat cancer itself or prevent its progression.
Pertzye may help manage digestive problems caused by pancreatic cancer or pancreatic surgery, improving nutrient absorption and supporting nutritional health.
Pertzye contains pancrelipase, a combination of pancreatic enzymes derived from porcine (pig) sources.
These enzymes work in the digestive tract to help break down food into smaller substances that can be absorbed by the body.
Pertzye contains three main digestive enzymes, each with a different function.
Lipase: Helps Digest Fats
Lipase breaks down dietary fats into smaller components, including fatty acids and monoglycerides.
These substances can then be absorbed through the small intestine.
Adequate fat digestion is also important for absorbing fat-soluble vitamins, including vitamins A, D, E, and K.
Protease: Helps Digest Proteins
Protease breaks down proteins into smaller peptides and amino acids.
These nutrients are essential for maintaining muscles, repairing tissues, supporting growth, and carrying out many normal bodily functions.
Amylase: Helps Digest Carbohydrates
Amylase breaks down starches and other complex carbohydrates into smaller sugars.
These sugars can then be absorbed and used by the body as a source of energy.
Pertzye capsules contain delayed-release particles designed to protect the enzymes as they pass through the stomach and release them in the small intestine.
This allows the enzymes to work where most nutrient digestion and absorption occur.
Pertzye works by supplying lipase, protease, and amylase to help the digestive system break down fats, proteins, and carbohydrates.Â
Pertzye begins working as the enzymes are released in the small intestine during digestion.
Unlike medications that must build up in the bloodstream over several weeks, Pertzye acts directly on food in the digestive tract.
When taken correctly with meals and snacks, the enzymes help break down nutrients during that digestive process.
Some patients may notice improvements in stool consistency, bloating, gas, or abdominal discomfort within several days of treatment.
However, the time needed for noticeable improvement varies depending on the severity of pancreatic insufficiency, the prescribed enzyme dose, and individual dietary habits.
Improvements in body weight and nutritional deficiencies may take longer because the body needs time to restore adequate nutrient levels.
Your healthcare provider will monitor your symptoms and may adjust your dosage based on your response to treatment.
Do not increase your enzyme dosage independently if symptoms continue.
Pertzye works during digestion, but noticeable symptom improvement varies. Consistent use with meals and snacks is important for effective treatment.
Pertzye is supplied as delayed-release capsules in different enzyme strengths. The dosage is measured primarily in lipase units and is individualized according to body weight, diet, age, and the severity of pancreatic insufficiency.
It should be taken during meals and snacks, as directed by your healthcare provider.
The capsules should be swallowed whole and must not be crushed or chewed. For patients who cannot swallow capsules, the contents may be sprinkled onto certain soft, acidic foods, such as applesauce, following the manufacturer’s specific instructions.
Pertzye is derived from pig pancreatic tissue, so patients with allergies or dietary concerns related to porcine products should discuss this with their healthcare provider.
Possible side effects include digestive discomfort, diarrhea, and other gastrointestinal symptoms. Excessively high doses of pancreatic enzymes have been associated with a serious intestinal condition called fibrosing colonopathy, particularly in children with cystic fibrosis.
Pertzye should not be automatically substituted with another pancreatic enzyme product because formulations and dosing requirements may differ.
Take Pertzye with meals and snacks exactly as prescribed. Do not crush or chew the enzyme particles, exceed the recommended dose, or switch pancreatic enzyme products without medical guidance.
Pertzye is a prescription pancreatic enzyme replacement medication used to treat exocrine pancreatic insufficiency (EPI), a condition in which the pancreas does not produce enough enzymes to digest food properly.
It contains pancrelipase, a combination of three digestive enzymes: lipase, protease, and amylase. These enzymes help the body break down fats, proteins, and carbohydrates so that nutrients can be absorbed in the small intestine.
Pertzye is available as delayed-release capsules that are taken with meals and snacks. The capsules contain specially formulated particles designed to protect the digestive enzymes as they pass through the stomach.
Pertzye works directly in the digestive system and must be taken with food to help break down the nutrients in each meal or snack.
Take Pertzye exactly as prescribed by your healthcare provider. Swallow the capsules whole when possible, and never crush or chew the capsules or their contents.
Pertzye should be taken by mouth during meals and snacks, according to your healthcare provider’s instructions.
Swallow the capsules whole with enough liquid to ensure they pass comfortably into the stomach.
The medication should be taken with food because the enzymes work by breaking down nutrients during digestion.
Taking Pertzye without food generally provides little benefit because there is no meal for the enzymes to digest.
Do not crush, chew, or break the delayed-release particles inside the capsules.
Damaging these particles may cause the enzymes to be released before they reach the small intestine, potentially reducing their effectiveness.
The enzymes may also irritate the lining of the mouth if they come into direct contact with oral tissues.
Your healthcare provider will determine the correct number of capsules based on your age, weight, medical condition, dietary fat intake, and response to treatment.
Take Pertzye with every meal and snack as prescribed. Swallow the capsules whole with sufficient liquid, and do not chew or crush them.
If you have trouble swallowing Pertzye capsules, your healthcare provider may recommend opening the capsule and administering the contents with a suitable soft food.
The delayed-release particles inside the capsule must remain intact.
For patients who cannot swallow capsules, the manufacturer allows the capsule contents to be sprinkled onto a small amount of soft, acidic food with a pH of 4.5 or lower, such as applesauce.
The food should be at room temperature and should not require chewing.
Carefully open the capsule and sprinkle the prescribed contents onto the food.
Swallow the mixture immediately without chewing.
After swallowing, drink water or juice to help ensure that all the medication has been swallowed and no enzyme particles remain in the mouth.
Do not mix the capsule contents with hot food or unsuitable liquids, as this may damage the protective coating surrounding the enzyme particles.
Do not store the mixture for later use.
If you cannot swallow Pertzye capsules whole, the contents may be sprinkled onto an appropriate acidic soft food, such as room-temperature applesauce. Swallow the mixture immediately without chewing.
Pertzye capsules contain delayed-release particles designed to release pancreatic enzymes in the small intestine.
These particles have a protective coating that helps prevent the enzymes from being released too early in the digestive tract.
Crushing or chewing the particles may damage this coating and expose the enzymes before they reach their intended location.
When pancreatic enzymes are released inside the mouth, they may irritate the tongue, gums, and other oral tissues.
This can cause soreness, discomfort, or irritation of the mouth.
Damaging the protective coating may also reduce the medication’s effectiveness because some enzymes may become inactive before reaching the small intestine.
For this reason, patients should avoid chewing the capsule contents, even when the particles are mixed with food.
If you notice particles remaining in your mouth after administration, drink additional water or juice to help swallow them.
Never crush or chew Pertzye capsules or their contents. Keeping the delayed-release particles intact helps protect the mouth and ensures that the enzymes reach the small intestine.
Pertzye should be taken with every meal and snack that requires pancreatic enzyme replacement, according to your healthcare provider’s instructions.
The medication works by providing digestive enzymes that help break down fats, proteins, and carbohydrates in food.
Because Pertzye acts during digestion, its effectiveness depends on taking the enzymes at the appropriate time.
Your healthcare provider will determine the number of capsules needed for meals and snacks based on your age, body weight, dietary fat intake, and severity of pancreatic insufficiency.
The prescribed dose for a snack may be lower than the dose recommended for a full meal.
Do not increase the number of capsules or exceed your prescribed daily dosage to compensate for digestive symptoms.
Excessive doses of pancreatic enzymes may increase the risk of serious gastrointestinal complications, including fibrosing colonopathy, a condition that can cause narrowing of the intestines.
Take Pertzye with meals and snacks as prescribed. Do not exceed your recommended enzyme dosage without consulting your healthcare provider.
Drinking sufficient fluids helps ensure that Pertzye capsules or delayed-release particles are swallowed completely.
This is particularly important for patients who open the capsules and mix their contents with soft food.
If enzyme particles remain in the mouth, they may irritate the tongue, gums, or lining of the cheeks.
Drinking water or juice immediately after administration helps wash any remaining particles into the digestive tract.
Adequate hydration is also important for general digestive health, especially for patients who experience diarrhea or other gastrointestinal symptoms.
However, patients with medical conditions that require fluid restrictions should follow their healthcare provider’s recommendations.
Drink enough water or juice to swallow Pertzye completely, unless your healthcare provider has advised you to limit fluid intake.
If you forget to take Pertzye with a meal or snack, do not take an additional dose later to make up for the missed medication.
Instead, take your next prescribed dose with your next meal or snack.
Pertzye works during digestion, so taking extra enzymes when you are not eating will not compensate for a previously missed dose.
Do not take two doses at the same time.
Taking more capsules than prescribed may increase the risk of side effects without improving digestion.
If you frequently miss doses or continue experiencing oily stools, bloating, diarrhea, or weight loss, contact your healthcare provider.
Your treatment plan may need to be reviewed to ensure you are receiving adequate enzyme replacement.
If you miss a dose of Pertzye, take your next scheduled dose with your next meal or snack. Never double the dose to make up for a missed one.Â
Pertzye may be prescribed to infants with exocrine pancreatic insufficiency, but administration differs from that used in older children and adults.
For infants from birth through 12 months of age, the prescribed dose is administered immediately before breastfeeding or formula feeding.
The manufacturer’s recommended dose for this age group is 4,000 lipase units per 120 mL of formula or per breastfeeding session.
The caregiver may carefully open the prescribed 4,000-unit capsule and administer its contents according to the healthcare provider’s instructions.
The particles may be sprinkled onto a small amount of suitable acidic soft food, such as applesauce, or administered directly into the infant’s mouth using the manufacturer’s approved method.
Breast milk or formula should be given immediately afterward to ensure the particles are swallowed.
Do not mix Pertzye particles directly into a bottle of breast milk or formula because this may reduce their effectiveness.
Caregivers should also inspect the infant’s mouth to ensure that no enzyme particles remain.
Pertzye administration in infants requires specific dosing and careful preparation. Always follow the pediatric healthcare provider’s instructions and the manufacturer’s administration guidelines.Â
Pertzye is a pancreatic enzyme replacement medication that should be taken exactly as prescribed.
The capsules and their contents must not be crushed or chewed because the digestive enzymes may irritate the mouth and become less effective.
Patients who cannot swallow capsules may open them and sprinkle the contents onto an appropriate soft, acidic food. The entire mixture must be swallowed immediately without chewing.
Do not mix the medication with unsuitable foods or liquids, and do not store a prepared mixture for later use.
Pertzye is derived from pig pancreatic tissue. Inform your healthcare provider if you have a known allergy to porcine proteins.
Contact your healthcare provider if you experience persistent abdominal discomfort, worsening diarrhea, constipation, unusual bowel symptoms, or continued signs of poor nutrient absorption.
Seek urgent medical attention for severe or persistent abdominal pain, significant abdominal swelling, or symptoms suggesting a serious allergic reaction.
Take Pertzye with meals and snacks, swallow the enzyme particles intact, drink sufficient fluids, and never exceed your prescribed dosage. Consult your healthcare provider if you have difficulty swallowing the medication or experience persistent digestive symptoms.
Pertzye (lipase/protease/amylase) is available in the following forms and strength:
Pertzye is a prescription pancreatic enzyme replacement medication used to treat exocrine pancreatic insufficiency (EPI), a condition in which the pancreas does not produce enough digestive enzymes to break down food properly.
It contains pancrelipase, a combination of three digestive enzymes: lipase, protease, and amylase. These enzymes help the body digest fats, proteins, and carbohydrates so that essential nutrients can be absorbed.
Although Pertzye can improve digestion and nutritional absorption, certain precautions are necessary to ensure safe and effective treatment.
Potential concerns include intestinal complications associated with excessive doses, mouth irritation, allergic reactions, and increased uric acid levels.
Pertzye should only be taken as prescribed. Do not increase your enzyme dosage, switch pancreatic enzyme products, or change your treatment schedule without consulting your healthcare provider.
Taking excessively high doses of Pertzye may increase the risk of a rare but serious intestinal condition called fibrosing colonopathy.
Fibrosing colonopathy occurs when abnormal scar tissue develops in the walls of the large intestine. Over time, this scarring may cause narrowing of the intestine, making it difficult for food waste to pass through normally.
This condition has been associated with high-dose pancreatic enzyme replacement therapy, particularly in children with cystic fibrosis.
Symptoms may include persistent abdominal pain, bloating, constipation, vomiting, and changes in bowel movements.
The recommended dosage of Pertzye is based primarily on the number of lipase units required to digest food.
For adults and children older than 12 months, the prescribing information recommends further evaluation before exceeding:
Higher doses may sometimes be necessary, but they should only be used when a healthcare provider has documented a clear clinical benefit and determined that the dosage is appropriate.
Patients receiving unusually high doses may require additional monitoring for symptoms of intestinal complications.
Do not exceed your prescribed Pertzye dosage. High-dose pancreatic enzyme therapy has been associated with fibrosing colonopathy, and doses above recommended limits require medical evaluation and supervision.Â
Pertzye should not be automatically substituted with another pancreatic enzyme replacement product.
Although different pancreatic enzyme medications contain similar digestive enzymes, their formulations, strengths, and methods of releasing enzymes may vary.
These differences can affect how efficiently the enzymes reach the small intestine and help digest food.
Switching products without adjusting the dosage may result in inadequate enzyme replacement or excessive enzyme exposure.
Patients who receive too few digestive enzymes may continue experiencing greasy stools, diarrhea, abdominal bloating, gas, or weight loss.
Your healthcare provider will consider your medical condition, diet, current enzyme dosage, and response to treatment before recommending a different product.
If a switch is necessary, your healthcare provider may monitor your digestive symptoms and gradually adjust the new dosage.
Do not switch from Pertzye to another pancrelipase product without medical guidance. Different pancreatic enzyme products are not automatically interchangeable and may require different dosing.Â
Patients who are pregnant or planning to become pregnant should consult their healthcare provider before using Pertzye.
Information about the use of Pertzye during pregnancy is limited.
However, available reports involving pancrelipase have not identified an increased risk of major birth defects, miscarriage, or other pregnancy complications associated with the medication.
Pancrelipase works primarily inside the digestive tract and is not absorbed into the bloodstream in significant amounts.
Therefore, exposure to the developing baby is expected to be very low.
Maintaining adequate nutrition during pregnancy is especially important for patients with exocrine pancreatic insufficiency.
Without sufficient digestive enzymes, the body may have difficulty absorbing fats, proteins, and essential vitamins needed for maternal health and fetal development.
Your healthcare provider will evaluate your nutritional requirements, medical condition, and treatment needs before recommending whether to continue Pertzye.
Pertzye is not known to pose a significant fetal risk because pancreatic enzymes are minimally absorbed into the bloodstream. However, treatment during pregnancy should be discussed with your healthcare provider.Â
Tell your healthcare provider if you are breastfeeding or planning to breastfeed while taking Pertzye.
There is limited information about whether pancrelipase passes into human breast milk.
However, pancreatic enzymes are not absorbed into the bloodstream in appreciable amounts after oral administration.
As a result, clinically significant exposure to a breastfed infant is not expected.
For patients with pancreatic insufficiency, continuing enzyme replacement may be necessary to support adequate digestion and nutrient absorption.
Proper nutrition is important during breastfeeding because the body requires additional energy and nutrients to support milk production.
Your healthcare provider will consider your need for treatment, the benefits of breastfeeding, and any potential concerns before recommending an appropriate treatment plan.
Pertzye is not expected to expose breastfed infants to significant amounts of pancreatic enzymes. Consult your healthcare provider before making changes to your treatment while breastfeeding.Â
Pertzye may cause irritation or damage to the lining of the mouth if the capsules or their contents are chewed, crushed, or retained in the mouth.
This occurs because Pertzye contains active digestive enzymes that break down fats, proteins, and carbohydrates.
When these enzymes come into direct contact with the tongue, gums, or inner cheeks, they may irritate the surrounding tissues.
Symptoms may include soreness, redness, burning, or discomfort inside the mouth.
Pertzye capsules contain delayed-release particles designed to protect the enzymes until they reach the small intestine.
Crushing or chewing these particles may damage their protective coating and cause the enzymes to be released too early.
Patients should swallow the capsules whole whenever possible.
If swallowing capsules is difficult, the contents may be sprinkled onto a small amount of soft, acidic food with a pH of 4.5 or lower, such as applesauce.
The mixture must be swallowed immediately without chewing.
After administration, drink enough water or juice to ensure that all enzyme particles have been swallowed.
Caregivers administering Pertzye to infants or patients who cannot swallow capsules should check that no particles remain inside the mouth.
Never crush or chew Pertzye capsules or their contents. Swallow the medication completely to prevent mouth irritation and protect the effectiveness of the digestive enzymes.Â
Before starting Pertzye, tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, and supplements you take.
Unlike many medications, Pertzye works primarily inside the digestive tract and is not significantly absorbed into the bloodstream.
As a result, interactions involving liver enzymes are not generally expected.
The prescribing information does not establish specific clinically significant interactions with anticoagulants or iron supplements.
However, patients who take these products should still inform their healthcare provider because changes in digestion and nutrient absorption may affect their overall treatment needs.
For example, patients with pancreatic insufficiency may require nutritional supplements to correct deficiencies caused by poor absorption.
Your healthcare provider may recommend monitoring nutritional status and adjusting supplements based on laboratory results.
Do not stop taking prescribed anticoagulants, iron supplements, or other medications without medical advice.
Pertzye has a relatively low potential for systemic drug interactions. Nevertheless, inform your healthcare provider about all medications and supplements you use to ensure your treatment remains appropriate.Â
Pertzye may increase uric acid levels in the blood, a condition called hyperuricemia.
Uric acid is a waste product produced when the body breaks down substances called purines.
Normally, the kidneys remove uric acid from the bloodstream through urine.
When uric acid levels become too high, crystals may accumulate in certain tissues, including the joints.
This can contribute to gout, a painful form of arthritis characterized by sudden episodes of joint swelling, redness, and tenderness.
High uric acid levels may also increase the risk of certain kidney stones.
Patients with a history of gout, elevated uric acid levels, or kidney impairment may be more susceptible to complications.
Your healthcare provider may recommend periodic blood tests to monitor uric acid levels during treatment.
Patients should also report new or worsening joint pain, swelling, or symptoms suggesting kidney stones.
Pertzye may increase uric acid levels. Patients with gout, hyperuricemia, or kidney disease should discuss their medical history with their healthcare provider and may require additional monitoring.Â
Pertzye contains pancreatic enzymes derived from pig pancreatic tissue.
Patients with a known allergy to porcine proteins should use Pertzye cautiously and inform their healthcare provider before starting treatment.
An allergic reaction occurs when the immune system responds abnormally to a substance that is usually harmless to most people.
Symptoms may include itching, skin rash, hives, redness, or swelling.
In some cases, patients may experience wheezing, breathing difficulties, or other respiratory symptoms.
Severe allergic reactions, including anaphylaxis, have been reported with pancreatic enzyme products.
Anaphylaxis is a potentially life-threatening allergic reaction that may cause swelling of the face, lips, tongue, or throat, along with difficulty breathing and a sudden drop in blood pressure.
Patients with known porcine protein allergies should discuss the potential risks and available treatment options with their healthcare provider.
Tell your healthcare provider if you have an allergy to pork or porcine proteins. Seek emergency medical attention if you develop difficulty breathing, throat swelling, or other signs of a severe allergic reaction.Â
There is no well-established direct interaction between Pertzye and alcohol.
Because Pertzye works primarily in the digestive tract and is not significantly absorbed into the bloodstream, alcohol is not expected to cause the same types of medication interactions seen with many systemically absorbed drugs.
However, alcohol consumption may still be a concern for patients with pancreatic conditions.
For example, alcohol can contribute to pancreatic inflammation and may worsen chronic pancreatitis.
Patients with chronic pancreatitis are generally advised to avoid alcohol because continued drinking can contribute to further pancreatic damage and complications.
Alcohol may also worsen digestive symptoms, including abdominal discomfort, nausea, and diarrhea.
For patients with pancreatic insufficiency related to chronic pancreatitis, avoiding alcohol may be an important part of the overall treatment plan.
Pertzye does not protect the pancreas from alcohol-related damage.
Your healthcare provider can advise whether alcohol should be completely avoided based on the underlying cause of your pancreatic insufficiency.
Although a direct interaction between Pertzye and alcohol has not been established, patients with chronic pancreatitis or alcohol-related pancreatic disease should avoid alcohol and follow their healthcare provider’s recommendations.
Pertzye is a pancreatic enzyme replacement medication that helps patients with exocrine pancreatic insufficiency digest food and absorb essential nutrients.
Although it is generally well tolerated, excessive doses may increase the risk of serious intestinal complications, including fibrosing colonopathy.
Patients with gout, kidney impairment, or elevated uric acid levels may require additional monitoring during treatment.
Because Pertzye is derived from pig pancreatic tissue, patients with allergies to porcine proteins should discuss this with their healthcare provider.
The capsules and their contents must not be crushed or chewed, as this may cause mouth irritation and reduce the medication’s effectiveness.
Patients who are pregnant or breastfeeding should consult their healthcare provider before making treatment changes.
Take Pertzye exactly as prescribed, avoid exceeding recommended enzyme doses, and contact your healthcare provider if you experience persistent abdominal pain, worsening digestive symptoms, or signs of an allergic reaction.
These precautions are not an exhaustive list of all possible warnings or side effects associated with Pertzye.
Yes. Pertzye is approved for use in children, including infants, who have exocrine pancreatic insufficiency (EPI) caused by cystic fibrosis or other pancreatic conditions. Exocrine pancreatic insufficiency occurs when the pancreas does not produce or release enough digestive enzymes to break down fats, proteins, and carbohydrates. Children with this condition may experience greasy or oily stools, diarrhea, abdominal bloating, poor weight gain, and difficulty absorbing essential nutrients. Pertzye contains three digestive enzymes: lipase, protease, and amylase. These enzymes help children digest food and absorb nutrients needed for healthy growth and development. The recommended dosage depends on the child’s age, body weight, dietary fat intake, and severity of pancreatic insufficiency. For infants younger than 12 months, Pertzye requires specific dosing and administration instructions. The medication is generally given immediately before breastfeeding or formula feeding. For older children, the medication is usually administered with meals and snacks. Parents and caregivers should follow the prescribed dosage carefully because excessive pancreatic enzyme doses have been associated with a rare but serious intestinal condition called fibrosing colonopathy, particularly in children with cystic fibrosis. Pertzye can be used in children, including infants, with exocrine pancreatic insufficiency. Dosing must be individualized and supervised by a healthcare provider to support proper digestion, nutrient absorption, and healthy growth.
Yes. Pertzye is a prescription medication and cannot be purchased as a regular over-the-counter digestive enzyme supplement. It is specifically formulated to replace pancreatic enzymes in patients diagnosed with exocrine pancreatic insufficiency. Pertzye contains pancrelipase, a combination of digestive enzymes that help break down fats, proteins, and carbohydrates in the small intestine. Because the amount of enzyme replacement needed varies between patients, a healthcare provider must determine the appropriate dosage. Factors such as age, body weight, dietary fat intake, medical condition, and response to treatment are considered when prescribing Pertzye. Taking too few enzymes may result in continued digestive symptoms and poor nutrient absorption. Taking excessive amounts may increase the risk of abdominal discomfort and serious intestinal complications, including fibrosing colonopathy. Pertzye should also not be automatically substituted with another pancreatic enzyme replacement product because different formulations may have different dosing requirements. Your healthcare provider may periodically assess your symptoms, weight, and nutritional status to determine whether your dosage needs adjustment. Pertzye requires a prescription because its dosage must be carefully individualized. Do not use it without medical supervision or substitute it with another pancreatic enzyme product without consulting your healthcare provider.
Pertzye begins working during the digestive process when the medication is taken with a meal or snack. It contains pancrelipase, a combination of three digestive enzymes: lipase, protease, and amylase. These enzymes help break down fats, proteins, and carbohydrates so the body can absorb essential nutrients. Unlike medications that need to build up in the bloodstream over several days or weeks, Pertzye works directly in the digestive tract. The delayed-release capsules contain specially coated enzyme particles that pass through the stomach and release their contents in the small intestine, where most nutrient digestion and absorption occur. Although Pertzye begins acting during the meal for which it is taken, noticeable improvements in digestive symptoms may take several days. Some patients may experience reduced bloating, gas, diarrhea, and greasy or oily stools as digestion improves. However, the time needed for improvement depends on the severity of pancreatic insufficiency, dietary habits, prescribed enzyme dosage, and individual response. Improvements in body weight and nutritional deficiencies may take several weeks or longer because the body needs time to restore adequate nutrient levels. Your healthcare provider may adjust your dosage if you continue experiencing symptoms of poor digestion or malabsorption. Pertzye starts working during digestion when taken with food. However, noticeable improvements in digestive symptoms may take several days, while nutritional improvements may require more time.Â
If you forget to take Pertzye with a meal or snack, skip the missed dose and take your next prescribed dose with your next meal or snack. Pertzye works by supplying digestive enzymes that help break down food as it moves through the digestive system. Because the medication acts directly on food, taking a missed dose after digestion has already progressed may not provide the intended benefit. Do not take an extra dose between meals to compensate for a missed application. You should also avoid taking two doses together because excessive pancreatic enzyme intake may increase the risk of side effects. If you frequently forget to take Pertzye, consider keeping your medication in an accessible location and incorporating it into your regular mealtime routine. For infants receiving Pertzye, caregivers should administer the next prescribed dose with the next feeding rather than attempting to replace a missed dose. If you continue experiencing greasy stools, abdominal bloating, diarrhea, or unexplained weight loss, contact your healthcare provider. These symptoms may indicate that your digestive enzyme replacement is insufficient or that your treatment schedule needs to be reviewed. Never double your Pertzye dose to make up for a missed dose. Take the next scheduled dose with your next meal or snack, and follow your healthcare provider’s instructions.Â
| Generic name: | Lipase/Protease/Amylase |
|---|---|
| Formulation: | Delayed Release Capsule |
| Strength(s): | 4000/14375/15125units |
| Quantities Available: | 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Pertzye (lipase/protease/amylase) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Pertzye is available in 4,000 units of lipase, 14,375 units of protease, and 15,125 units of amylase per capsule. The prescribed dosage usually depends on individual needs and can vary. For example, if you are prescribed 4 capsules per meal and 3 meals per day, that’s 12 capsules per day. For a 90-day supply, you would order 1,080 capsules (90 days x 12 capsules per day).
No, we do not sell lipase/protease/amylase directly on our website. However, you can still enjoy low prices on Pertzye, which contains lipase, protease, and amylase as active ingredients. To purchase Pertzye, you will need a valid prescription from your healthcare provider. We require this to dispense the medication safely and appropriately. You can submit your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Pertzye (lipase/protease/amylase) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Pertzye (Lipase/Protease/Amylase). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Pertzye (Lipase/Protease/Amylase).
REVIEWS