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Formulation: Tablet
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Formulation: Tablet
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Otezla (active ingredient: apremilast) is a prescription medication used to treat psoriatic arthritis and moderate to severe plaque psoriasis in adults.
Otezla belongs to a group of medications called phosphodiesterase 4 (PDE4) inhibitors. It works by helping regulate the immune system and reducing inflammation that contributes to the symptoms of psoriatic arthritis and plaque psoriasis.
Otezla is used to treat active psoriatic arthritis, a chronic inflammatory condition that affects the joints and is often associated with psoriasis.
Psoriatic arthritis can cause symptoms such as:
By helping reduce inflammation, Otezla may improve joint symptoms and help patients maintain daily activities and mobility.
How Otezla Helps with Psoriatic Arthritis
Otezla is also used to treat moderate to severe plaque psoriasis in adults who may be candidates for phototherapy (light therapy) or systemic treatment.
Plaque psoriasis is a long-term autoimmune skin condition that causes raised, red patches of skin covered with silvery scales. These patches commonly appear on the scalp, elbows, knees, and lower back but can occur anywhere on the body.
Common Symptoms of Plaque Psoriasis
How Otezla Helps with Plaque Psoriasis
Otezla works by blocking an enzyme called phosphodiesterase 4 (PDE4). This enzyme plays a role in regulating inflammation within the body.
By reducing the activity of PDE4, Otezla helps lower the production of inflammatory substances that contribute to the symptoms of psoriatic arthritis and plaque psoriasis. As inflammation decreases, symptoms such as joint pain, swelling, skin redness, and scaling may improve over time.
Because Otezla works gradually, it may take several weeks of regular treatment before you begin to notice its full benefits.
Otezla is available as an oral tablet and should be taken exactly as prescribed by your healthcare provider. The medication may be taken with or without food and is usually taken twice daily.
Swallow the tablets whole. Do not crush, split, or chew the tablets, as this may affect how the medication works and could increase the risk of side effects.
Your dose of Otezla will depend on your medical condition, kidney function, and how well you respond to treatment. To help reduce the risk of side effects, treatment is usually started at a lower dose and gradually increased over the first several days. This process is known as dose titration and allows your body time to adjust to the medication.
Follow your healthcare provider’s instructions carefully and continue taking Otezla even if you do not notice immediate improvement. It may take several weeks before the full benefits of treatment become noticeable.
Initial Titration Schedule
To reduce the risk of side effects, Otezla is typically started using a 5-day titration schedule. Your healthcare provider will provide specific instructions on how to gradually increase your dose during this period.
Maintenance Dosage
After completing the titration schedule, the recommended maintenance dose is:
If you miss a dose or have questions about your dosing schedule, contact your healthcare provider or pharmacist for guidance.
Otezla (Apremilast) is available in the following forms and strength:
Older adults may be more likely to experience complications from severe diarrhea, nausea, or vomiting while taking Otezla. Contact your healthcare provider if any of these symptoms become severe, persistent, or lead to dehydration.
Before starting Otezla, tell your healthcare provider and pharmacist about any allergies you may have. Otezla contains inactive ingredients that may cause allergic reactions or other unwanted effects in some people.
If you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed, discuss this with your healthcare provider before taking Otezla. Your healthcare provider can help you understand the potential benefits and risks of treatment and determine whether Otezla is appropriate for your situation.
Stop taking Otezla and seek immediate medical attention if you develop symptoms of a serious allergic reaction. Symptoms may include:
These symptoms may indicate a severe allergic reaction that requires emergency medical care.
While taking Otezla, your healthcare provider may monitor your weight regularly. Some people experience significant or unexplained weight loss during treatment. If you notice a noticeable decrease in your weight, inform your healthcare provider. They may evaluate the cause and determine whether treatment should be continued.
Before starting Otezla, tell your healthcare provider if you have a history of depression, suicidal thoughts, or other mental health concerns. In some people, Otezla may cause new or worsening mood changes.
Contact your healthcare provider immediately if you experience:
Regular follow-up appointments can help your healthcare provider monitor your response to treatment and identify any side effects or concerns early during therapy.
Yes. Otezla is approved for the treatment of active psoriatic arthritis in adults. It helps reduce inflammation associated with the condition and may improve symptoms such as joint pain, swelling, stiffness, and reduced mobility. Otezla can also be used to treat moderate to severe plaque psoriasis in adults who are candidates for phototherapy or systemic treatment.
Otezla works gradually, so you may not notice immediate improvement after starting treatment. Some people begin to see benefits within a few weeks, while for others it may take several months to experience the full effects of the medication. To help reduce the risk of side effects, treatment is usually started with a lower dose that is gradually increased over the first several days. Continue taking Otezla exactly as prescribed, even if you do not notice immediate results.
It is generally recommended to limit or avoid alcohol while taking Otezla. Alcohol may increase the risk of certain side effects, such as dizziness, nausea, or stomach upset. If you drink alcohol regularly, speak with your healthcare provider about whether alcohol consumption is appropriate while taking Otezla.
If you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed, discuss this with your healthcare provider before taking Otezla. The effects of Otezla during pregnancy and breastfeeding are not fully known. Your healthcare provider can help you weigh the potential benefits and risks of treatment and determine whether Otezla is an appropriate option for you and your baby.
| Generic name: | Apremilast |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 10mg, 20mg, 30mg |
| Quantities Available: | 16, 40, 180 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Otezla (apremilast) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Otezla is commonly prescribed in dosages of 10 mg, 20 mg, or 30 mg taken orally twice daily. For a 90-day supply, you would order 180 tablets (90 days x 2 tablets per day).
Yes, we sell apremilast. You can enjoy low prices on this medication when you order from us. You will need a valid prescription from your healthcare provider to purchase apremilast. We require this to dispense the medication. You can mail, fax, or upload your prescription through your online account.
Yes, we ship Otezla (apremilast) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Otezla (Apremilast). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Otezla (Apremilast).
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