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Nexletol (active ingredient: bempedoic acid) is a prescription medication used to help lower LDL (“bad”) cholesterol levels in adults who need additional cholesterol reduction despite following a healthy diet and taking cholesterol-lowering medications.
Nexletol is commonly prescribed for people with heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes high cholesterol levels, or for those with established atherosclerotic cardiovascular disease (ASCVD), such as a history of heart attack, stroke, or other cardiovascular conditions.
Nexletol is typically used in addition to lifestyle changes and other cholesterol-lowering therapies, including statins, when further LDL cholesterol reduction is needed.
Nexletol is indicated as an adjunct to diet and maximally tolerated statin therapy for adults with:
These patients often require additional LDL cholesterol lowering to help reduce their risk of future cardiovascular events.
How Nexletol Helps
Nexletol belongs to a class of medications known as ATP-citrate lyase inhibitors.
It works by blocking an enzyme in the liver called ATP-citrate lyase, which plays an important role in cholesterol production. By reducing cholesterol synthesis in the liver, Nexletol helps lower the amount of LDL cholesterol circulating in the bloodstream.
As LDL cholesterol levels decrease, the risk of cholesterol buildup in the arteries may also be reduced, helping to support heart and blood vessel health.
For best results, Nexletol should be used alongside a heart-healthy diet, regular exercise, and any other cholesterol-lowering medications prescribed by your healthcare provider.
Nexletol is available as an oral tablet and is typically taken once daily, with or without food, exactly as prescribed by your healthcare provider.
For the best results, take Nexletol at the same time each day. Taking the medication consistently helps maintain steady levels in your body and improves its effectiveness.
Swallow the tablet whole and continue taking it even if you feel well. High cholesterol usually does not cause noticeable symptoms, so it is important to continue treatment as directed, even when you do not feel any different.
The usual recommended dose of Nexletol is:
Your healthcare provider will determine whether Nexletol is appropriate for you and may monitor your cholesterol levels throughout treatment.
Nexletol begins lowering cholesterol after treatment starts, but it may take several weeks before the full effects are seen.
In many patients, it can take up to 12 weeks to achieve the maximum cholesterol-lowering benefit. Your healthcare provider may perform periodic blood tests to monitor your LDL cholesterol levels and assess your response to treatment.
Regular use of Nexletol, combined with healthy lifestyle habits, can help support long-term cholesterol management and cardiovascular health.
Nexletol (Bempedoic Acid) is available in the following forms and strength:
Before taking Nexletol, tell your healthcare provider about your complete medical history, including any allergies, medical conditions, and medications you take.
Do not take Nexletol if you are allergic to bempedoic acid or any of the ingredients in the medication.
Seek immediate medical attention if you develop signs of a serious allergic reaction, such as:
Nexletol may increase the risk of tendon injury, including tendon rupture.
The risk may be higher in people who:
Contact your healthcare provider immediately if you experience:
If you have liver disease or kidney disease, your healthcare provider may monitor you more closely during treatment.
Regular blood tests may be recommended to help assess liver and kidney function while taking Nexletol.
Nexletol may increase uric acid levels and can trigger gout flare-ups in some people.
Tell your healthcare provider if you have a history of gout or develop symptoms such as:
If you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed, talk to your healthcare provider before taking Nexletol.
The safety of Nexletol during pregnancy and breastfeeding has not been fully established. Your healthcare provider will determine whether the potential benefits of treatment outweigh any potential risks.
Nexletol may interact with other medications, vitamins, herbal products, and supplements.
Before starting treatment, tell your healthcare provider about everything you take, including:
This helps reduce the risk of potential drug interactions.
Some people may experience muscle pain, tenderness, or weakness while taking Nexletol.
Although uncommon, muscle symptoms may occasionally be a sign of a serious condition called rhabdomyolysis, which involves muscle breakdown and can lead to kidney problems.
Contact your healthcare provider if you develop unexplained muscle pain, weakness, or severe muscle symptoms.
Nexletol may cause dizziness or blurred vision in some people.
Until you know how the medication affects you, avoid driving, operating machinery, or performing activities that require alertness and clear vision.
If you are scheduled for surgery or a medical procedure, tell your healthcare provider that you are taking Nexletol.
Your healthcare team can determine whether any special precautions are needed before, during, or after the procedure.
Regular follow-up appointments and cholesterol monitoring can help ensure Nexletol remains safe and effective throughout your treatment.
Nexletol may interact with certain medications, vitamins, herbal products, and supplements. Before starting treatment, tell your healthcare provider about everything you take, including prescription medications, over-the-counter products, vitamins, and herbal supplements. Your healthcare provider can review your medications and determine whether any adjustments are needed to help prevent potential drug interactions.
The safety of Nexletol during pregnancy and breastfeeding has not been fully established. If you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed, talk to your healthcare provider before taking Nexletol. Your healthcare provider will determine whether the potential benefits of treatment outweigh any potential risks.
Nexletol begins lowering LDL (“bad”) cholesterol after treatment starts, but it may take several weeks before noticeable improvements are seen in blood test results. Many patients achieve the full cholesterol-lowering benefits after approximately 12 weeks of regular treatment. Your healthcare provider may perform periodic blood tests to monitor your cholesterol levels and assess your response to therapy.
People with liver or kidney problems may still be able to take Nexletol, but additional monitoring may be required. Your healthcare provider may evaluate your liver and kidney function before and during treatment and determine whether any dosage adjustments or special precautions are necessary.
Nexletol is generally used as a long-term treatment for managing high cholesterol. The length of treatment depends on your individual health needs, cholesterol levels, treatment goals, and response to therapy. Your healthcare provider will determine how long you should continue taking Nexletol and will monitor your progress through regular follow-up appointments and blood tests.
| Generic name: | Bempedoic, Bempedoic Acid |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 180mg |
| Quantities Available: | 84, 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Nexletol (bempedoic acid) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is standard practice for prescription medications to ensure continuous treatment without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Nexletol is commonly prescribed in a dosage of 180 mg once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).
Yes, we do sell bempedoic acid on our website. You can enjoy low prices for this medication. However, please note that you will need a valid prescription from your healthcare provider in order to purchase bempedoic acid from us. We require this prescription to dispense the medication safely and legally. You can conveniently provide your prescription by mailing, faxing, or uploading it through your online account on our website.
Yes, we ship Nexletol (bempedoic acid) to both the United States and Puerto Rico.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Nexletol (Bempedoic). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Nexletol (Bempedoic).
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