Tricor Nanocrystallized (Fenofibrate Nanocrystallized)

Indications

Tricor Nanocrystallized is used to treat high cholesterol and triglyceride levels in the blood. It is often prescribed in combination with lifestyle changes such as diet and exercise, to help reduce the risk of heart attack and stroke.

Tricor Nanocrystallized is a formulation of the medication fenofibrate. Fenofibrate works by reducing the levels of triglycerides and increasing the levels of high-density lipoprotein (HDL) cholesterol in the blood. It achieves this by activating peroxisome proliferator-activated receptor alpha (PPARα), which controls the expression of genes involved in lipid metabolism. This results in increased lipolysis and elimination of triglycerides from the blood.

Use and Dosage

Tricor Nanocrystallized should be taken orally with a glass of water once a day, with or without food. The tablet should not be crushed or chewed, as it can affect the way the medication is absorbed. It should be swallowed whole with water. Avoid consuming grapefruit or grapefruit juice while taking the tablet, as it can increase the risk of side effects.

Take the tablet regularly and at the same time each day. With respect to dosage, do not exceed the prescribed amounts nor use it more frequently or for longer periods of time. Continue taking the medication even if you do not feel ill as high cholesterol/triglycerides do not produce symptoms. Taking more than the recommended dose will not accelerate the reduction of cholesterol/triglycerides levels, but rather, can increase the risk of side effects.

Side Effects

Common Side Effects of Tricor Nanocrystallized (Fenofibrate Nanocrystallized):

• Abdominal pain
• Allergic reactions such as rash or itching
• Constipation
• Diarrhea
• Dizziness
• Headache
• Muscle pain
• Nausea

Serious Side Effects of Tricor Nanocrystallized (Fenofibrate Nanocrystallized):

• Agitation
• Bloating
• Bloody urine
• Chronic indigestion
• Constipation
• Dark urine
• Decreased frequency or amount of urine
• Difficulty in moving
• Fast heartbeat
• General tiredness and weakness
• Increased blood pressure
• Increased thirst
• Indigestion
• Joint pain or swelling
• Light-colored stools
• Loss of appetite
• Lower back or side pain
• Muscle cramps, spasms, stiffness, swelling, or weakness
• Pains in the stomach, side, or abdomen, radiating to the back
• Pale skin
• Swelling of the face, fingers, or lower legs
• Troubled breathing
• Troubled breathing with exertion
• Unusual bleeding or bruising
• Unusual tiredness or weakness
• Upper right abdominal or stomach pain
• Weight gain
• Yellow eyes or skin

Forms and Strength

Tricor Nanocrystallized (Fenofibrate Nanocrystallized) is available in the following forms and strength:

Tobi Podhaler Capsules: Nanocrystallized Tablet

• 48 mg

Cautions

• Do not take fenofibrate if you are allergic to it or have gallbladder disease.
• Fenofibrate can cause liver problems. Inform your doctor if you have liver disease and be sure to have regular liver function tests.
• Fenofibrate can increase the risk of developing pancreatitis. Inform your doctor if you have a history of pancreatitis or if you experience severe abdominal pain.
• Fenofibrate can interact with other medications, including blood thinners, cyclosporine, and certain statin medications. Inform your doctor of all prescription and over-the-counter medications you are taking.
• Fenofibrate can cause muscle damage (rhabdomyolysis) which can sometimes be severe and lead to kidney failure. Inform your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness while taking fenofibrate.
• Fenofibrate can increase the risk of developing blood clots. Inform your doctor if you have a history of blood clots or if you experience symptoms such as chest pain, shortness of breath, or leg swelling.
• Fenofibrate can cause gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal discomfort. Inform your doctor if these symptoms persist or are severe.
• Fenofibrate can cause an increase in blood sugar levels. Inform your doctor if you have diabetes, as you may need to have your blood sugar levels monitored more closely.
• Fenofibrate may affect the thyroid gland and alter thyroid hormone levels. Inform your doctor if you have a history of thyroid problems or if you experience symptoms such as fatigue, weight gain, or cold intolerance.

Frequently Asked Questions (FAQ)

How long does it take for Tricor Nanocrystallized to work?

Tricor Nanocrystallized can start to work within a few weeks, but it may take up to 2 to 3 months to see the full cholesterol-lowering effects.

Can Tricor Nanocrystallized be taken with other cholesterol-lowering medications?

Tricor Nanocrystallized may be taken with other cholesterol-lowering medications but consult with a healthcare provider to ensure proper use and avoid potential interactions.

What should I do if I miss a dose of Tricor Nanocrystallized?

If a dose of Tricor Nanocrystallized is missed, it should be taken as soon as possible. However, if it is close to the time for the next scheduled dose, it may be skipped, and the regular dosing schedule resumed.

How should Tricor Nanocrystallized be stored?

Tricor Nanocrystallized should be stored at room temperature and protected from light and moisture. It should be kept out of the reach of children and pets.

Resources

• https://www.drugs.com/fenofibrate.html
• https://www.webmd.com/drugs/2/drug-144771/fenofibrate-nanocrystallized-oral/details
• https://www.clevelandclinicmeded.com/medicalpubs/pharmacy/septoct2004/tricor.htm
• https://www.goodrx.com/fenofibrate/what-is#tips
• https://my.clevelandclinic.org/health/drugs/20555-fenofibrate-tablets