Indications
Lopid scientifically known as gemfibrozil, a medication used to help lower triglycerides and raise "good" cholesterol (HDL) in the blood. It is classified as a lipid regulating agent and belongs to a group of drugs known as fibrates.
Lopid works by decreasing the amount of fat produced by the liver and can help in reducing cholesterol and triglycerides (fatty acids) in the blood. Lopid may not be effective in reducing the risk of heart disease in people with normal cholesterol levels. It is typically used in combination with a proper diet to achieve these effects.
Uses and Dosage
Lopid is a tablet that is taken orally twice daily, 30 minutes prior to the morning and evening meals, as per your doctor’s instructions. The appropriate dosage will be determined by your medical condition and response to treatment. If you are taking other drugs, such as bile acid-binding resins (e.g., cholestyramine or colestipol), to lower your cholesterol, you should take gemfibrozil at least 1 hour before or 4-6 hours after taking these medications. This is because bile acid-binding resins can interfere with gemfibrozil's absorption.
To experience the full benefits of this medication, take it regularly at the same time each day. Even if you feel well, continue taking the medication as prescribed, as most people with high cholesterol/triglyceride do not experience symptoms. Remember to adhere to your doctor’s recommended diet and exercise regime, as it may take up to 3 months to see the full effect of the medication.
When administer gemfibrozil (Lopid), it is recommended to take one tablet (600 mg) orally, twice a day, at least 30 minutes prior to breakfast and dinner.
Side Effect
Common Side Effects of Lopid (Gemfibrozil):
- Cold symptoms such as stuffy nose, sneezing, or sore throat
- Diarrhea
- Difficulty having an orgasm
- Dizziness
- Drowsiness
- Headache
- Impotence
- Nausea
- Unusual taste
- Vomiting
Serious Side Effects of Lopid (Gemfibrozil):
- Dark urine
- Persistent nausea or vomiting
- Severe stomach/abdominal pain
- Yellowing eyes or skin
- Joint or muscle pain
- Loss of interest in sex
- Numbness or tingly feeling
- Stomach upset
- Stomach/abdominal pain
Form and Strength
Lopid (Gemfibrozil) is available in the following forms and strengths:
Lopid: Tablet
- 600 mg
Gemfibrozil: Tablet
- 600 mg
Caution
- The drug can cause a significant decrease in certain types of blood fats, including triglycerides and cholesterol, as well as an increase in blood levels of "good" cholesterol (HDL). However, the increase in HDL has not been shown to translate into a decrease in the risk of cardiovascular disease.
- If you miss a dose of Lopid, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. It is important to not take extra doses of Lopid to make up for a missed dose.
- Lopid can interact with other medications, including blood thinners, and may increase the risk of side effects or reduce the effectiveness of the medication. It may also interact with certain vitamins and supplements.
- People with liver, kidney, or gallbladder disease should use Lopid with caution, as the drug can worsen these conditions.
- Lopid can also cause side effects such as upset stomach, diarrhea, and muscle pain.
- Lopid may cause gastrointestinal side effects like stomach upset, abdominal pain, and nausea.
- Lopid may cause muscle pain or weakness, which can be a sign of a serious muscle condition called rhabdomyolysis.
- Lopid may interact with other medications or supplements, discuss any other drugs you are taking with your healthcare provider before starting Lopid.
- Lopid may cause liver or kidney problems in some people, so it should be used with caution in those with underlying liver or kidney disease.
- Lopid may increase your risk for gallstones, tell your healthcare provider if you have a history of gallstone disease before taking Lopid.
- Lopid may not be effective in reducing the risk of heart disease in people with normal cholesterol levels.
Frequently Asked Questions (FAQ)
How should I take Lopid?
Lopid should be taken by mouth with meals and should be taken exactly as prescribed by your healthcare provider.
Can I drink alcohol while taking Lopid?
Do not drink alcohol while taking Lopid because it can increase the risk of liver problems.
Can I take Lopid if I am pregnant or breastfeeding?
Lopid is not recommended for use during pregnancy or breastfeeding because the potential risks to a developing fetus or nursing infant are not known.
How long does it take for Lopid to start working?
Lopid may take several weeks to start working, and it may take several months to see the full benefits of the medication.
Can I stop taking Lopid if I feel better?
Do not stop taking Lopid without first consulting with your healthcare provider, even if you feel better. Your healthcare provider will determine the appropriate duration of treatment with Lopid based on your individual needs.
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