Before taking Medrol, tell your healthcare provider about your medical history, allergies, and all medications or supplements you are taking. This helps your provider determine whether Medrol is safe for you and whether you need closer monitoring during treatment.
Allergic Reactions
Before using methylprednisolone, tell your healthcare provider if you are allergic to methylprednisolone, prednisone, or any other medications. Medrol may contain inactive ingredients that can cause allergic reactions or other problems in some people.
Ask your pharmacist if you have questions about the ingredients in your medication. Seek medical help right away if you develop symptoms of a serious allergic reaction, such as rash, swelling of the face or throat, severe dizziness, or trouble breathing.
Take Only as Prescribed
Do not increase your dose, take Medrol more often, or use it for longer than prescribed. Taking more than directed will not make your condition improve faster and may increase your risk of side effects.
Do Not Stop Suddenly
Do not stop taking Medrol without talking to your healthcare provider. Stopping suddenly may cause withdrawal symptoms, especially if you have taken it for a long time or at higher doses.
Withdrawal symptoms may include weakness, weight loss, nausea, muscle pain, headache, tiredness, and dizziness. If Medrol needs to be stopped, your healthcare provider may gradually lower your dose to help your body adjust safely.
Bone and Growth Effects
Long-term use of Medrol may weaken bones and increase the risk of bone loss, osteoporosis, and fractures, especially in adults and older adults.
In children and infants, long-term corticosteroid use may slow growth. A healthcare provider may monitor growth and development during treatment if Medrol is used for an extended period.
Stomach Bleeding Risk
Medrol may increase the risk of stomach irritation, ulcers, or stomach bleeding, especially when used with alcohol or certain medications such as NSAIDs.
Limit alcoholic beverages while taking Medrol. Daily alcohol use can further increase the risk of stomach bleeding. Contact your healthcare provider right away if you develop severe stomach pain, black or tarry stools, or vomit that looks like coffee grounds.
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