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Evalon Cream (estriol) is a prescription estrogen replacement medication used to relieve vaginal and vulvar symptoms caused by declining estrogen levels during menopause.
Evalon Cream contains estriol 1 mg/g, a form of estrogen that helps restore the health, moisture, and elasticity of vaginal tissues affected by estrogen deficiency.
During menopause, the ovaries gradually produce less estrogen. This hormonal change can cause the tissues lining the vagina and surrounding vulvar area to become thinner, drier, and less elastic.
These changes may lead to vaginal dryness, itching, burning, irritation, and discomfort during sexual activity.
Evalon Cream works by delivering estriol directly to the vaginal tissues, where it helps improve the effects of estrogen deficiency and relieve uncomfortable symptoms.
Your healthcare provider may prescribe Evalon Cream to treat vaginal atrophy and other menopause-related changes affecting the lower genital and urinary tract.Â
Vaginal atrophy, also called atrophic vaginitis, occurs when declining estrogen levels cause the vaginal lining to become thinner, drier, and more fragile.
This condition is common after menopause and is now often included under the broader term genitourinary syndrome of menopause (GSM).
GSM describes changes affecting the vagina, vulva, and lower urinary tract that develop because of reduced estrogen activity.
Vaginal atrophy can cause persistent discomfort and may interfere with everyday activities and sexual health.
Evalon Cream helps improve vaginal tissue health by replacing estrogen locally.
The medication may help relieve the following symptoms:
Although Evalon Cream can improve these symptoms, it does not permanently reverse menopause or restore the ovaries’ natural estrogen production.
Symptoms may return after treatment is discontinued.
Evalon Cream may also be prescribed to treat vulvar and vaginal changes associated with estrogen deficiency.
The vulva refers to the external genital structures surrounding the vaginal opening. Like the vagina, these tissues respond to estrogen.
When estrogen levels decline during menopause, the vulvar and vaginal tissues may become thinner, less elastic, and more sensitive.
These changes can contribute to dryness, irritation, discomfort, and pain during sexual activity.
Evalon Cream helps improve tissue health by restoring estrogen activity in the affected area.
Potential benefits include:
Your healthcare provider will determine whether Evalon Cream is appropriate based on your symptoms, medical history, and the severity of estrogen deficiency.
Evalon Cream contains estriol, a naturally occurring estrogen hormone.
Estriol belongs to a class of medications called estrogen replacement therapies.
Estrogen plays an important role in maintaining the structure, thickness, elasticity, and moisture of vaginal tissues.
Before menopause, the ovaries produce estrogen that helps keep the vaginal lining healthy and supports the normal balance of bacteria and acidity in the vagina.
As estrogen levels decline, the vaginal lining may become thinner, less elastic, and more vulnerable to dryness and irritation.
Evalon Cream works by delivering estriol directly to the vaginal tissues, helping replace the local effects of declining estrogen.
Once absorbed into vaginal cells, estriol binds to estrogen receptors and activates processes that support normal tissue growth and maintenance.
Restores Estrogen Activity in Vaginal Tissues
Estriol binds to estrogen receptors found in cells lining the vagina and surrounding tissues.
These receptors help regulate how vaginal cells grow, mature, and maintain their structure.
When estriol activates these receptors, it helps restore some of the normal functions that decline after menopause.
This can improve tissue thickness, moisture, and flexibility.
Because Evalon Cream is administered vaginally, its primary treatment effects occur in the tissues where the medication is applied. However, some estriol can also enter the bloodstream.
Improves Vaginal Moisture and Elasticity
Estrogen helps maintain vaginal tissues that are flexible, well-hydrated, and resistant to irritation.
During menopause, reduced estrogen levels can cause these tissues to become thin and dry.
Estriol helps support the development and maintenance of healthy vaginal epithelial cells, which make up the vaginal lining.
As the vaginal lining improves, tissues may become more elastic and less vulnerable to friction.
This can help relieve vaginal dryness, irritation, and discomfort during sexual activity.
Helps Restore Normal Vaginal pH
Before menopause, estrogen helps maintain a vaginal environment in which beneficial bacteria, particularly Lactobacillus species, can thrive.
These bacteria produce lactic acid, which helps maintain the vagina’s naturally acidic environment.
When estrogen levels decline, the vaginal lining produces less glycogen, a substance that helps support beneficial vaginal bacteria.
As a result, vaginal pH may rise, and the normal balance of microorganisms may change.
Evalon Cream helps restore estrogen activity in vaginal tissues, supporting healthier epithelial cells and a more normal vaginal environment.
By improving vaginal tissue health and acidity, estriol may help reduce irritation and some urinary or vaginal symptoms associated with estrogen deficiency.
However, Evalon Cream is not an antibiotic or antifungal medication and should not be used alone to treat an active vaginal infection.
Reduces Vaginal Dryness and Painful Intercourse
Vaginal dryness and tissue thinning can increase friction during sexual activity, making intercourse painful or uncomfortable.
Estriol helps restore the thickness, flexibility, and moisture of vaginal tissues.
As the vaginal lining becomes healthier, it may tolerate friction more comfortably.
This can reduce menopause-related vaginal discomfort and improve comfort during sexual activity.
Estrogen receptors are also present in tissues surrounding the urethra and lower urinary tract.
Declining estrogen levels during menopause can contribute to urinary symptoms, including discomfort during urination, urinary urgency, and recurrent urinary tract infections in some women.
By improving estrogen activity in the surrounding tissues, vaginal estriol may help support lower urinary tract health.
However, the benefit varies depending on the specific urinary condition.
Evalon Cream does not replace antibiotics when a bacterial urinary tract infection is present.
If you experience persistent burning during urination, fever, blood in your urine, or significant urinary discomfort, contact your healthcare provider for evaluation.
Evalon Cream begins delivering estriol to vaginal tissues after application, but noticeable symptom improvement may take several weeks.
Some women may notice reduced dryness, itching, or irritation within the first few weeks of treatment.
However, improvements in vaginal tissue thickness, elasticity, and painful intercourse may take longer.
The response depends on the severity of your symptoms, how consistently you use the medication, and your individual response to estrogen treatment.
Your healthcare provider may recommend daily application during the first few weeks, followed by a lower maintenance schedule as symptoms improve.
Do not increase the amount of cream or use it more frequently than prescribed.
If your symptoms do not improve or become worse, contact your healthcare provider.
Evalon Cream is a vaginal estrogen medication and should be used according to your healthcare provider’s instructions.
The manufacturer’s product information describes an initial daily treatment schedule for vaginal atrophy, followed by a gradual reduction to a maintenance schedule, such as twice-weekly use.
A calibrated vaginal applicator is provided to help measure and administer the prescribed amount of cream.
Evalon Cream should not be used during pregnancy or breastfeeding. Tell your healthcare provider if you have unexplained vaginal bleeding, a history of breast cancer or other estrogen-sensitive cancers, blood clots, or significant liver disease.
Although estriol is applied locally, some medication may be absorbed into the bloodstream, so your healthcare provider should review your medical history before treatment.
Evalon Cream helps relieve vaginal dryness, itching, irritation, and painful intercourse caused by estrogen deficiency during menopause. By restoring estrogen activity in vaginal tissues, it can improve moisture, elasticity, and overall tissue comfort.
Evalon Cream is a prescription vaginal estrogen medication used to relieve dryness, irritation, itching, and discomfort caused by declining estrogen levels during menopause.
The medication works by delivering estriol directly to the vaginal tissues, helping restore moisture, improve tissue elasticity, and reduce symptoms associated with vaginal atrophy.
Evalon Cream is intended for intravaginal use only, meaning it is applied inside the vagina using the applicator provided with the medication.
Your healthcare provider will determine the appropriate dosage, application frequency, and treatment duration based on your symptoms, medical history, and response to treatment.
Evalon Cream is often prescribed once daily at bedtime during the initial treatment period. As your symptoms improve, your healthcare provider may recommend reducing the frequency to a maintenance schedule.
Always follow your prescribed instructions and do not apply more medication than recommended.
Follow these steps to administer Evalon Cream safely and correctly:
Using Evalon Cream at bedtime may help the medication remain in contact with the vaginal tissues while you are lying down.
The dosage of Evalon Cream depends on the severity of your vaginal symptoms and how well you respond to estrogen treatment.
For vaginal atrophy associated with menopause, your healthcare provider may recommend applying Evalon Cream once daily during the initial treatment period.
As vaginal dryness, irritation, and discomfort improve, the application frequency may be reduced.
A maintenance schedule may involve using the cream twice weekly, depending on your prescribed treatment plan.
Your healthcare provider will determine the amount of cream required for each application and the appropriate length of treatment.
Do not continue daily treatment for longer than recommended or increase the amount of cream without medical advice.
Apply Evalon Cream at Bedtime
Evalon Cream is often recommended for use at bedtime.
Applying the medication before going to sleep allows you to remain lying down after administration, which may help reduce leakage and improve convenience.
Choose a consistent bedtime routine to help you remember your prescribed applications.
A small amount of cream may leak from the vagina after use. This is not necessarily a sign that the medication was applied incorrectly.
You may use an unscented panty liner if needed to protect your underwear.
Avoid using tampons to absorb excess cream, as they may remove some of the medication.
Use Only the Prescribed Amount
Evalon Cream contains estriol, an estrogen hormone that acts on vaginal tissues.
Although it is applied locally, some estriol can be absorbed into your bloodstream.
Using more cream than prescribed may increase estrogen exposure and the risk of side effects.
Always measure the dose using the supplied applicator and follow your healthcare provider’s instructions.
Do not apply additional cream if you do not notice immediate improvement.
Insert the Applicator Gently
Vaginal tissues affected by estrogen deficiency may be thinner, drier, and more sensitive.
For this reason, insert the applicator slowly and carefully to avoid discomfort or irritation.
If you experience pain, significant resistance, or bleeding during insertion, stop and contact your healthcare provider.
Never force the applicator into your vagina.
Clean the Applicator After Each Use
Proper applicator hygiene helps prevent contamination.
If the applicator supplied with your Evalon Cream is reusable, separate the plunger and barrel after each application.
Wash both parts with mild soap and warm water, rinse them thoroughly, and allow them to dry completely.
Avoid using boiling water, harsh cleaning agents, or disinfectants unless specifically recommended by the manufacturer.
If the applicator is disposable, discard it after use rather than attempting to clean and reuse it.
Avoid Vaginal Douching and Harsh Products
The vagina has a natural environment that helps maintain tissue health and protect against irritation.
Vaginal douching, scented soaps, and heavily fragranced products may disrupt this environment or worsen vaginal dryness.
While using Evalon Cream, clean the external genital area gently with water and avoid unnecessary internal washing.
If you use vaginal moisturizers, lubricants, or other vaginal medications, ask your healthcare provider how to schedule them alongside Evalon Cream.
If you forget to use Evalon Cream, apply the missed dose as soon as you remember, provided it is within 12 hours of your usual application time.
If more than 12 hours have passed, skip the missed dose and continue with your regular treatment schedule.
Do not use two doses on the same day to make up for a missed application. Using extra cream may increase estrogen exposure without improving your symptoms.
If you frequently miss applications or are unsure when to resume treatment, contact your healthcare provider or pharmacist for advice.Â
Evalon Cream begins delivering estriol to the vaginal tissues after application, but symptom relief may take several weeks.
Some women notice a gradual improvement in vaginal dryness, itching, burning, and irritation during the first few weeks of treatment.
Improvements in vaginal tissue thickness, moisture, and elasticity may take longer to become noticeable.
The time needed to experience relief depends on the severity of your symptoms, how consistently you apply the medication, and your individual response to treatment.
Continue using Evalon Cream as prescribed, even if your symptoms do not improve immediately.
If your symptoms persist or become worse, contact your healthcare provider rather than increasing the amount of cream.
Contact your healthcare provider if you experience persistent vaginal burning, itching, unusual discharge, irritation, or discomfort while using Evalon Cream.
You should also report any unexpected vaginal bleeding or spotting, particularly if you are postmenopausal. Unexplained bleeding should be evaluated to determine whether additional testing or a change in treatment is necessary.
Seek emergency medical attention if you develop sudden chest pain, difficulty breathing, or painful swelling in one leg, as these may be signs of a serious blood clot.
Evalon Cream is intended to relieve vaginal symptoms caused by estrogen deficiency. It should not be used during pregnancy or breastfeeding.
Always use Evalon Cream exactly as prescribed. Applying the correct amount with the supplied applicator, maintaining proper hygiene, and following your recommended treatment schedule can help relieve vaginal dryness and irritation while reducing the risk of unwanted side effects.
Evalon Cream (Estriol) is available in the following forms and strength:
Before using Evalon Cream, tell your healthcare provider about your medical history, existing health conditions, allergies, and any medications you are taking.
Evalon Cream is a vaginal estrogen medication used to relieve dryness, itching, irritation, and discomfort caused by declining estrogen levels during menopause.
Although Evalon Cream is applied directly inside the vagina, some estriol may enter your bloodstream. For this reason, certain health conditions may require additional precautions or make estrogen treatment unsuitable.
Tell your healthcare provider if you have a history of breast cancer, blood clots, stroke, heart disease, liver disease, or unexplained vaginal bleeding.
Your healthcare provider will assess your individual risks before recommending treatment and may advise regular medical examinations during use.
Evalon Cream should not be used without specialist evaluation if you have a history of estrogen-dependent cancer, including certain types of breast cancer.
Some cancer cells contain estrogen receptors that allow estrogen to stimulate their growth. Because Evalon Cream contains estriol, it may not be suitable for people with known or suspected hormone-sensitive tumors.
Although vaginal estrogen generally results in less systemic exposure than estrogen tablets or patches, some estriol may still enter your bloodstream.
The risks associated with vaginal estriol are not necessarily the same as those associated with higher-dose systemic hormone replacement therapy. However, caution is important, particularly if you have previously received treatment for breast cancer or another estrogen-sensitive condition.
Tell your healthcare provider if you have a personal history of breast cancer, endometrial cancer, or another hormone-sensitive tumor.
Warning signs that require medical evaluation include:
If you have previously been treated for breast cancer, your healthcare provider may recommend nonhormonal vaginal treatments first.
If these are not effective, low-dose vaginal estrogen may sometimes be considered after a careful discussion involving your healthcare provider and cancer specialist.
Do not start Evalon Cream if you have known or suspected estrogen-dependent cancer without medical advice.
Estrogen therapy may increase the risk of blood clots in certain individuals.
A blood clot that forms in a deep vein, usually in the leg, is called deep vein thrombosis (DVT).
If part of the clot breaks loose and travels to the lungs, it can cause a pulmonary embolism, which is a potentially life-threatening condition.
Low-dose vaginal estrogen generally has less effect on blood-clotting factors than systemic estrogen therapy. However, Evalon Cream may still be unsuitable for individuals with certain clotting disorders or a history of serious blood clots.
Tell your healthcare provider if you have previously experienced DVT, pulmonary embolism, or another blood-clotting problem.
Possible symptoms of a blood clot include:
Seek emergency medical attention immediately if you develop sudden chest pain, difficulty breathing, coughing up blood, or symptoms suggesting a pulmonary embolism.
If you notice unexplained swelling or pain in one leg, seek urgent medical evaluation.
Tell your healthcare provider if you have a history of stroke, heart attack, or other cardiovascular conditions before using Evalon Cream.
Estrogen can affect blood vessels and certain processes involved in blood clotting.
Studies of systemic hormone replacement therapy have identified increased risks of stroke and certain cardiovascular problems in some groups of women.
However, these findings cannot be directly applied to every low-dose vaginal estrogen treatment because the amount of estrogen entering the bloodstream is generally much lower.
Your healthcare provider will consider your medical history and determine whether Evalon Cream is appropriate.
Additional cardiovascular risk factors may include high blood pressure, diabetes, smoking, high cholesterol, and a personal history of cardiovascular disease.
Warning signs of a stroke include sudden weakness or numbness on one side of your body, difficulty speaking, facial drooping, sudden vision changes, or a severe unexplained headache.
Symptoms of a heart attack may include chest pressure, pain spreading to your arm or jaw, shortness of breath, sweating, or nausea.
Seek emergency medical attention immediately if you experience symptoms of a stroke or heart attack.
Evalon Cream should not be used to prevent cardiovascular disease.
If you have liver disease or a history of serious liver problems, tell your healthcare provider before using Evalon Cream.
The liver plays an important role in processing estrogen and removing it from your body.
Although Evalon Cream is administered vaginally, some estriol may enter the bloodstream and eventually be processed by the liver.
If your liver is not functioning normally, estrogen metabolism may be affected.
This may increase hormone exposure or make treatment inappropriate for certain individuals.
Tell your healthcare provider if you have cirrhosis, hepatitis, a history of liver tumors, or abnormal liver function tests.
Possible warning signs of liver problems include:
Your healthcare provider may recommend liver function tests if you have a history of liver disease.
Contact your healthcare provider promptly if you develop symptoms suggesting liver problems.
Do not use Evalon Cream if you have unexplained vaginal bleeding until your healthcare provider has determined the cause.
Bleeding after menopause can occur for several reasons, including vaginal tissue thinning, uterine polyps, endometrial changes, or, less commonly, cancer.
Because Evalon Cream contains estrogen, unexpected bleeding should be evaluated before treatment begins.
Some women may experience mild spotting or changes in vaginal discharge during treatment. However, persistent, recurring, or heavy vaginal bleeding should not be ignored.
Contact your healthcare provider if you experience bleeding after menopause, particularly if you have not had a menstrual period for 12 months or longer.
Your healthcare provider may recommend a pelvic examination, ultrasound, or endometrial biopsy when appropriate.
Stop using Evalon Cream and contact your healthcare provider if you develop unexpected or excessive vaginal bleeding. Further evaluation may be needed before treatment can safely continue.
Tell your healthcare provider if you have a blood-clotting disorder or a family history of abnormal blood clots before using Evalon Cream.
Certain inherited conditions, such as protein C deficiency, protein S deficiency, or antithrombin deficiency, can increase the likelihood of developing blood clots.
People with these conditions may already have a higher risk of deep vein thrombosis or pulmonary embolism.
Although Evalon Cream is applied vaginally and generally produces lower systemic estrogen exposure than oral hormone therapy, some estriol can still enter your bloodstream.
According to the manufacturer’s prescribing information, Evalon Cream should not be used in people with known thrombophilic disorders or a history of venous thromboembolism.Â
Your healthcare provider may ask about blood clots affecting your parents, siblings, or other close relatives.
If you have a known clotting disorder, your healthcare provider can recommend a different treatment for vaginal dryness and irritation.
Tell your healthcare provider if you have recently undergone surgery, are planning major surgery, or expect to remain inactive for an extended period.
Major surgery and prolonged immobilization can increase the risk of developing blood clots, particularly in people who already have other risk factors.
For example, remaining in bed for an extended period after surgery may slow blood circulation in the legs, increasing the likelihood of clot formation.
Your healthcare provider will determine whether Evalon Cream should be continued or temporarily interrupted based on your medical history, the type of surgery, and your individual blood-clotting risk.
Do not stop or restart treatment without medical advice.
If you experience sudden leg swelling, calf pain, chest pain, or difficulty breathing after surgery, seek immediate medical attention.
Tell your healthcare provider if you have a history of endometriosis, uterine fibroids, or other conditions affecting your uterus or ovaries.
Endometriosis occurs when tissue similar to the lining of the uterus grows outside the uterus. This tissue can respond to estrogen and may contribute to inflammation, pelvic pain, and other symptoms.
Uterine fibroids are noncancerous growths that develop in or around the uterus. Some fibroids are sensitive to estrogen and may change in size or cause symptoms when hormone levels fluctuate.
Because Evalon Cream contains estriol, your healthcare provider should consider whether estrogen exposure could affect these conditions.
Although vaginal estriol typically produces less systemic estrogen exposure than oral hormone therapy, additional monitoring may be needed if you have a history of endometriosis or fibroids.
Contact your healthcare provider if you develop persistent pelvic pain, unusual abdominal pressure, or unexpected vaginal bleeding during treatment.
If you have a history of endometrial hyperplasia, tell your healthcare provider before using Evalon Cream.
Endometrial hyperplasia occurs when the lining of the uterus becomes unusually thick. It can develop when the endometrium is exposed to estrogen without sufficient progesterone activity.
Certain forms of endometrial hyperplasia can increase the risk of endometrial cancer.
Low-dose vaginal estriol generally produces less stimulation of the uterine lining than systemic estrogen therapy. However, prolonged or excessive estrogen exposure may still require additional precautions.
The manufacturer’s prescribing information advises that the maximum daily application should not be continued for longer than the recommended initial treatment period. Maintenance treatment typically uses a lower application frequency.Â
Your healthcare provider will determine whether Evalon Cream is appropriate based on your uterine health and previous medical history.
Do not use more cream or continue daily treatment longer than prescribed.
Report any unexpected vaginal bleeding or spotting promptly.
Do not use Evalon Cream if you are allergic to estriol or any other ingredient in the formulation.
An allergic reaction may occur when your immune system responds to an ingredient in the medication.
Possible symptoms include increased vaginal itching, burning, redness, swelling, or a new rash around the application area.
Mild local irritation can sometimes occur when starting vaginal estrogen treatment. However, persistent or worsening symptoms may indicate sensitivity to the medication.
If you develop severe burning, unusual swelling, or a worsening rash, stop using Evalon Cream and contact your healthcare provider.
Seek emergency medical attention immediately if you experience difficulty breathing or swelling of your face, lips, tongue, or throat.
Evalon Cream is intended to treat vaginal symptoms caused by estrogen deficiency, particularly after menopause. It is not intended for use during pregnancy or breastfeeding.
If you are pregnant, planning to become pregnant, or think you may be pregnant, tell your healthcare provider before starting treatment.
Evalon Cream contains estriol, an estrogen hormone. Although the medication is applied locally, some estriol may enter your bloodstream.
If pregnancy occurs during treatment, discontinue Evalon Cream and contact your healthcare provider for further advice, as recommended in the manufacturer’s prescribing information.Â
If you are breastfeeding, consult your healthcare provider before using Evalon Cream. Estrogen may affect milk production, and the safety of this specific treatment during breastfeeding has not been adequately established.
Your healthcare provider may recommend a nonhormonal vaginal moisturizer or another treatment depending on your symptoms and medical needs.
Regular medical reviews are important if you use Evalon Cream over an extended period.
Your healthcare provider will assess whether your vaginal symptoms are improving and whether the medication remains appropriate.
Tell your healthcare provider about any new medical conditions, unexpected bleeding, breast changes, or symptoms that develop during treatment.
You should also report changes in your medications, particularly if you begin hormone therapy or treatment for another significant medical condition.
Use Evalon Cream at the lowest effective dose and follow the recommended maintenance schedule.
Do not increase your dose or extend the initial daily treatment period without medical supervision.
Contact your healthcare provider if you develop persistent vaginal irritation, unusual discharge, unexpected spotting, pelvic pain, or breast changes while using Evalon Cream.
You should also seek medical advice if your symptoms do not improve or return frequently despite treatment.
Seek emergency medical attention immediately if you experience sudden chest pain, difficulty breathing, coughing up blood, sudden weakness on one side of your body, or symptoms of a serious allergic reaction.
Stop using Evalon Cream and contact your healthcare provider promptly if you develop jaundice, a new migraine-type headache, a significant increase in blood pressure, or pregnancy.
Evalon Cream can help relieve vaginal dryness, irritation, and discomfort caused by estrogen deficiency, but certain medical conditions may make treatment unsuitable. Following the prescribed dosage, reporting unusual symptoms, and attending regular medical reviews can help ensure safer and more effective treatment.
Evalon Cream is a prescription vaginal estrogen medication used to relieve symptoms of vaginal atrophy caused by declining estrogen levels during menopause. Vaginal atrophy occurs when lower estrogen levels cause the vaginal lining to become thinner, drier, and less elastic. These changes can lead to vaginal dryness, itching, burning, irritation, and discomfort during sexual intercourse. Evalon Cream contains estriol, a naturally occurring estrogen hormone that helps restore estrogen activity in vaginal tissues. When applied inside the vagina, estriol helps improve tissue moisture, thickness, and elasticity, making the affected area more comfortable. The medication may also help support the vagina’s natural acidic environment, which can change as estrogen levels decline during menopause. Evalon Cream primarily acts on vaginal tissues, although a small amount of estriol may enter the bloodstream. Evalon Cream does not cure menopause or permanently reverse vaginal atrophy. However, regular use as prescribed can help manage symptoms and improve vaginal comfort. Your healthcare provider will determine the appropriate dosage and treatment duration based on the severity of your symptoms, medical history, and response to treatment.
No, Evalon Cream is not suitable for everyone. Although it can effectively relieve vaginal dryness and irritation caused by estrogen deficiency, certain medical conditions may make treatment unsafe or require additional precautions. Evalon Cream contains estriol, an estrogen hormone that acts mainly on vaginal tissues. However, some estriol can be absorbed into the bloodstream, so your healthcare provider must consider your medical history before recommending treatment. Women with a history of estrogen-sensitive cancers, including certain types of breast cancer and endometrial cancer, may not be suitable candidates for Evalon Cream. The medication may also be inappropriate for women with a history of blood clots, deep vein thrombosis, pulmonary embolism, stroke, serious liver disease, or certain inherited blood-clotting disorders. If you experience unexplained vaginal bleeding, your healthcare provider should investigate the cause before you begin estrogen treatment. You should also tell your healthcare provider if you have a history of endometriosis, uterine fibroids, or other conditions affecting your reproductive organs. Women who are allergic to estriol or any other ingredient in Evalon Cream should not use the medication. Your healthcare provider will assess your individual health risks, menopausal symptoms, and treatment needs to determine whether Evalon Cream is appropriate. Do not begin using Evalon Cream without consulting your healthcare provider. If estrogen therapy is unsuitable, your healthcare provider may recommend nonhormonal vaginal moisturizers, lubricants, or other treatment options.
Evalon Cream is not recommended for use during pregnancy or breastfeeding. The medication contains estriol, an estrogen hormone used to relieve vaginal symptoms associated with declining estrogen levels, particularly after menopause. Because Evalon Cream is intended for estrogen deficiency, it is not a treatment for vaginal symptoms related to pregnancy. Although estriol is applied directly inside the vagina, some medication may enter your bloodstream. There is limited information about the safety of this specific formulation during pregnancy. If you are pregnant, planning to become pregnant, or think you may be pregnant, tell your healthcare provider before using Evalon Cream. If you become pregnant while using Evalon Cream, stop treatment and contact your healthcare provider for advice. Accidental exposure does not necessarily mean harm has occurred, but your healthcare provider should review the situation. If you are breastfeeding, it is important to discuss treatment with your healthcare provider because estrogen medications may affect milk production. The amount of estriol that may pass into breast milk after vaginal application has not been adequately established for this product. Your healthcare provider can recommend another treatment if you experience vaginal dryness or discomfort during breastfeeding. Nonhormonal vaginal moisturizers and lubricants may be appropriate alternatives, depending on your symptoms and medical needs.
Evalon Cream is applied directly inside the vagina using the applicator supplied with the medication. The cream delivers estriol to the vaginal tissues, where it helps relieve dryness, itching, irritation, and discomfort associated with estrogen deficiency. Evalon Cream is often prescribed once daily at bedtime during the initial treatment period. As your symptoms improve, your healthcare provider may recommend reducing the application frequency to a maintenance schedule, such as twice weekly. Before applying Evalon Cream, wash your hands thoroughly with soap and water. Gently clean the external vaginal area with lukewarm water if necessary, and pat it dry. Avoid washing inside the vagina or using harsh soaps and scented products. Remove the cap from the cream tube and attach the supplied vaginal applicator. Gently squeeze the tube until the applicator contains the prescribed amount of medication, using the measurement marking if provided. Carefully remove the applicator from the tube and replace the cap. Lie on your back with your knees bent and slightly apart. Gently insert the applicator into your vagina as far as it comfortably goes, without forcing it. Slowly press the plunger until it reaches its stopping point to release the cream. Then carefully remove the applicator. If your applicator is reusable, separate the plunger from the barrel and wash both parts with mild soap and warm water. Rinse thoroughly and allow them to dry before storing. Follow the manufacturer’s instructions for your specific applicator. Applying Evalon Cream at bedtime may help reduce leakage and allow the medication to remain in contact with vaginal tissues while you are lying down. Use only the amount prescribed by your healthcare provider. Applying extra cream or using it more frequently will not necessarily provide faster relief and may increase estrogen exposure. Some women notice improvements in vaginal dryness and irritation within the first few weeks of treatment, while others may need longer to experience noticeable relief. Always follow your prescribed dosage and application schedule. Contact your healthcare provider if you experience persistent vaginal irritation, unexpected bleeding, unusual discharge, or worsening discomfort during treatment.
| Generic name: | Estriol |
|---|---|
| Formulation: | Cream |
| Strength(s): | 1mg |
| Quantities Available: | 15g, 45g |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Evalon Cream (estriol) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Evalon Cream is available in a strength of 1 mg of estriol per gram of cream. It is typically applied to the vaginal area once daily, with a dose of up to 2 mg per day. For a 90-day supply, if you use 2 mg of estriol per day, you would order up to 180 mg (90 days x 2 mg per day).
No, we do not sell estriol directly on our website. However, you can still enjoy low prices on Evalon Cream, which contains estriol as an active ingredient. To purchase Evalon Cream, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You can submit your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Evalon Cream (estriol) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Evalon Cream (Estriol). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Evalon Cream (Estriol).
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