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Formulation: Capsule
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Dibenzyline (phenoxybenzamine) is a prescription medication used to control high blood pressure and excessive sweating caused by a rare tumor called pheochromocytoma. It helps relax your blood vessels, allowing blood to flow more easily and reducing pressure on your heart.
Pheochromocytoma usually develops in the adrenal glands, which are small glands located above your kidneys. These glands produce hormones that help control your blood pressure, heart rate, and response to stress.
When you have pheochromocytoma, the tumor can release too much of certain hormones, called catecholamines. These hormones can cause sudden or ongoing high blood pressure, a rapid heartbeat, headaches, and excessive sweating.
Your healthcare provider may prescribe Dibenzyline to help manage the following condition:
Dibenzyline does not remove or cure pheochromocytoma. Instead, it helps control symptoms and reduce the risk of complications caused by excessive hormone release.
Your healthcare provider will determine the appropriate dose based on your blood pressure, symptoms, and overall health. Regular monitoring is important because Dibenzyline can sometimes cause your blood pressure to drop too low.
Dibenzyline belongs to a group of medications called alpha-adrenergic blockers, also known as alpha-blockers. These medications help relax blood vessels and lower blood pressure.
Your body naturally produces hormones called adrenaline and noradrenaline. These hormones help control your heart rate, blood pressure, and the body’s response to stressful situations.
Normally, these hormones attach to special areas on your blood vessels called alpha-adrenergic receptors. When these receptors are activated, your blood vessels become narrower, causing your blood pressure to rise.
In people with pheochromocytoma, the tumor releases excessive amounts of these hormones. This can cause blood vessels to tighten too much, leading to dangerously high blood pressure and other symptoms.
Dibenzyline works by blocking alpha-adrenergic receptors, preventing adrenaline and noradrenaline from causing excessive narrowing of your blood vessels.
The medication works in several ways:
Dibenzyline does not stop the tumour from producing hormones. Instead, it reduces how strongly these hormones affect your blood vessels.
Because the medication relaxes your blood vessels, it may cause dizziness, lightheadedness, or fainting, especially when you stand up too quickly. Your healthcare provider may gradually adjust your dose to help reduce these effects.
Important: Dibenzyline should be taken only under the supervision of a healthcare provider experienced in treating pheochromocytoma. Your blood pressure and heart rate may need to be checked regularly to make sure the medication is working safely and effectively.
Dibenzyline is a prescription medication taken by mouth to help control high blood pressure and excessive sweating caused by pheochromocytoma, a rare tumour that usually develops in the adrenal glands.
Dibenzyline comes in capsule form and is usually taken two or three times a day, depending on your prescribed dose and treatment plan. You can take the medication with or without food.
Your healthcare provider will determine the right dose based on your blood pressure, medical condition, and response to treatment.
Take Dibenzyline at the same times each day to help maintain consistent blood pressure control. Always follow the instructions on your prescription label.
Starting Dose
The usual starting dose of Dibenzyline for adults with pheochromocytoma is 10 mg twice daily.
Your healthcare provider may begin with this lower dose to see how your body responds to the medication. Starting with a low dose also helps reduce the risk of dizziness, fainting, and sudden drops in blood pressure.
Dose Adjustments
If your blood pressure remains higher than your target range, your healthcare provider may gradually increase your dose.
Dose adjustments are usually made every few days, depending on your blood pressure readings, symptoms, and how well you tolerate the medication.
Your healthcare provider will monitor you closely during this period to make sure your blood pressure does not drop too low.
Do not increase or decrease your dose without medical advice.
Usual Maintenance Dose
The usual total daily dose of Dibenzyline ranges from 20 mg to 100 mg, divided into two or three doses.
Some people may need a different dose depending on their condition and response to treatment.
Your healthcare provider will aim to find a dose that controls your blood pressure and symptoms without causing excessive dizziness or other side effects.
Follow these simple steps to take Dibenzyline safely and correctly:
Take Your Medication Regularly
Take Dibenzyline at the same times each day to help control your blood pressure and manage your symptoms.
Setting a phone reminder or using a medication schedule may help you remember your doses.
If you have trouble following your prescribed schedule, ask your healthcare provider or pharmacist for advice.
Stand Up Slowly
Dibenzyline relaxes your blood vessels, which can sometimes cause your blood pressure to drop too low when you stand up.
This may lead to dizziness, lightheadedness, weakness, or fainting.
To reduce these symptoms, get up slowly when moving from a lying or sitting position to standing. If you feel dizzy, sit or lie down until you feel better.
Contact your healthcare provider if you frequently experience dizziness or feel like you might faint.
Monitor Your Blood Pressure
Your healthcare provider may recommend checking your blood pressure regularly while taking Dibenzyline.
Keeping a record of your readings can help your healthcare provider understand how well the medication is working and whether your dose needs to be adjusted.
Tell your healthcare provider if your blood pressure remains unusually high or drops too low.
Do Not Change Your Dose
Do not take extra capsules or increase your dose if your blood pressure remains high.
Taking too much Dibenzyline can cause a dangerous drop in blood pressure, which may lead to severe dizziness, fainting, or weakness.
If your prescribed dose does not seem to control your symptoms, contact your healthcare provider. They may gradually adjust your treatment.
Do Not Stop Treatment Without Medical Advice
Continue taking Dibenzyline for as long as your healthcare provider recommends.
Although Dibenzyline is not considered addictive, stopping treatment may allow symptoms of pheochromocytoma, including dangerously high blood pressure, to return.
If you need to stop taking the medication, your healthcare provider will explain how and when to discontinue treatment safely.
Attend Regular Medical Appointments
Your healthcare provider may recommend regular appointments to monitor your blood pressure, heart rate, and response to treatment.
If you are preparing for pheochromocytoma surgery, your healthcare team will closely monitor your condition and adjust your medication to help reduce the risk of dangerous blood pressure changes during the procedure.
Contact your healthcare provider if you experience frequent dizziness, unusual weakness, a rapid heartbeat, or blood pressure readings that are consistently outside your recommended range.
Seek emergency medical attention if you develop severe chest pain, difficulty breathing, fainting, or a sudden severe headache accompanied by very high blood pressure.
Always take Dibenzyline exactly as prescribed. Following your treatment schedule, monitoring your blood pressure, and attending regular medical appointments can help manage pheochromocytoma symptoms while reducing the risk of serious complications.
Dibenzyline (Phenoxybenzamine) is available in the following forms and strength:
Before taking Dibenzyline, tell your healthcare provider about any medical conditions, allergies, or medications you are taking. Although Dibenzyline helps control high blood pressure and sweating caused by pheochromocytoma, it can also cause side effects, especially if you have certain health conditions.
Your healthcare provider may recommend regular blood pressure monitoring and medical checkups to make sure the medication is working safely.
Long-term use of Dibenzyline is generally not recommended because of concerns about a possible increased risk of cancer.
Studies in animals have shown that prolonged exposure to phenoxybenzamine can cause certain types of tumours. There have also been reports of cancer in people who received long-term treatment, although these reports do not prove that the medication caused the cancer.
If you need Dibenzyline for an extended period, your healthcare provider will carefully consider the benefits and possible risks.
Do not stop taking the medication without medical advice, as uncontrolled blood pressure caused by pheochromocytoma can be dangerous.Â
Dibenzyline works by blocking alpha-adrenergic receptors, which help control how tightly your blood vessels contract.
When these receptors are blocked, your blood vessels relax and your blood pressure decreases. However, other receptors called beta-adrenergic receptors remain active.
Certain medications, such as epinephrine, can stimulate both types of receptors. When taken with Dibenzyline, they may cause an unexpected and potentially dangerous drop in blood pressure along with a rapid heartbeat.
Tell your healthcare provider that you are taking Dibenzyline before receiving emergency treatment, undergoing surgery, or starting medications that affect your blood pressure or heart rate.Â
Dibenzyline may interact with medications that affect your blood pressure, heart rate, or blood circulation.
For example, taking Dibenzyline with certain blood pressure medications may increase your risk of dizziness, weakness, or dangerously low blood pressure.
Some medications used for heart problems, nasal congestion, or emergency treatment may also interact with Dibenzyline.
Tell your healthcare provider or pharmacist about all the medications you take, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements.
Do not start, stop, or change any medication without checking with your healthcare provider.
Dibenzyline may cause dizziness, tiredness, nausea, or weakness, especially when you first begin treatment or your dose is increased.
These symptoms may occur because the medication relaxes your blood vessels and lowers your blood pressure.
If you feel dizzy or lightheaded, sit or lie down until you feel better. Avoid standing up too quickly, as this may make your symptoms worse.
Contact your healthcare provider if these side effects become severe, continue for a long time, or interfere with your daily activities.
Tell your healthcare provider if you have asthma or chronic obstructive pulmonary disease (COPD) before taking Dibenzyline.
Although Dibenzyline is not commonly associated with directly narrowing the airways, its effects on certain nerve signals may worsen symptoms associated with respiratory infections.
If you already have breathing problems, your healthcare provider may recommend closer monitoring during treatment.
Contact your healthcare provider if you develop worsening coughing, wheezing, or shortness of breath. Seek immediate medical attention if you have severe difficulty breathing.
If you have kidney disease, tell your healthcare provider before taking Dibenzyline.
The medication lowers blood pressure, which may affect blood flow to your kidneys, especially if your blood pressure drops too low.
People with significant kidney problems may need closer monitoring to make sure their blood pressure remains within a safe range.
Your healthcare provider may recommend checking your kidney function and adjusting your treatment based on your condition.
Contact your healthcare provider if you notice reduced urination, unusual swelling, or persistent dizziness.
Tell your healthcare provider if you have liver disease or a history of liver problems.
Although significant liver damage is not a commonly recognized side effect of Dibenzyline, your healthcare provider should review your medical history before starting treatment.
They may recommend additional monitoring depending on your condition and other medications.
Do not change your dose without medical advice.
Some medications that affect alpha-adrenergic receptors can interfere with the normal process that ends an erection.
Priapism is a prolonged erection that may become painful and is not related to sexual stimulation. It is not a well-established common side effect of Dibenzyline, but you should tell your healthcare provider if you have a history of priapism or sickle cell anemia.
Seek emergency medical attention if you develop an erection lasting four hours or longer. Without prompt treatment, priapism can cause permanent tissue damage.
Dibenzyline affects certain nerve signals involved in blood vessel function. These changes may affect how your body responds to temperature changes.
Some people may feel unusually warm, cold, flushed, or dizzy, particularly in hot environments.
Try to avoid becoming overheated, and be careful when moving between very hot and cold environments.
If you experience persistent dizziness, weakness, or unusual discomfort during temperature changes, contact your healthcare provider.
Dibenzyline can cause postural hypotension, which happens when your blood pressure drops after you stand up from a sitting or lying position.
This can cause dizziness, lightheadedness, blurred vision, weakness, or fainting.
The risk may be higher when you first start taking Dibenzyline, after a dose increase, or if you are dehydrated.
To reduce your risk, stand up slowly and use support if you feel unsteady. Your healthcare provider may recommend checking your blood pressure while sitting and standing.
Contact your healthcare provider if you frequently feel dizzy or experience fainting episodes.
Dibenzyline may cause drowsiness, dizziness, or reduced alertness in some people.
These effects may make it harder to drive, operate machinery, or perform activities that require concentration and coordination.
Avoid these activities until you know how the medication affects you.
If you continue to experience significant drowsiness or dizziness, contact your healthcare provider. Your dose may need to be reviewed.
Tell your healthcare provider if you have heart disease, congestive heart failure, coronary artery disease, or other problems affecting your heart.
Dibenzyline can lower blood pressure and sometimes cause your heart to beat faster. These effects may be concerning if you already have a heart condition.
Your healthcare provider may monitor your blood pressure and heart rate closely during treatment.
Contact your healthcare provider if you experience frequent palpitations, unusual weakness, or worsening swelling.
Seek emergency medical attention if you develop chest pain, fainting, or severe shortness of breath.
If you have a history of depression, bipolar disorder, or another mental health condition, tell your healthcare provider before starting Dibenzyline.
Dibenzyline is not well established as a direct cause of worsening depression or bipolar disorder. However, symptoms such as fatigue, dizziness, and weakness may affect how you feel during treatment.
Your healthcare provider can review your medications and determine whether additional monitoring is needed.
Contact your healthcare provider if you notice significant changes in your mood, behaviour, or overall well-being.
Contact your healthcare provider if you experience frequent dizziness, unusual tiredness, nausea, a rapid heartbeat, or blood pressure readings that are consistently outside your recommended range.
Seek emergency medical attention if you develop severe chest pain, difficulty breathing, fainting, or a sudden severe headache accompanied by dangerously high blood pressure.
Always take Dibenzyline exactly as prescribed. Regular blood pressure monitoring, following your treatment schedule, and attending medical appointments can help manage pheochromocytoma symptoms while reducing the risk of serious complications.
Dibenzyline begins working after you take it, but it may take several days to notice its full effects on your blood pressure. The time it takes to work depends on your prescribed dose, medical condition, and how your body responds to treatment. Your healthcare provider may gradually increase your dose over several days or weeks until your blood pressure is well controlled. If you are taking Dibenzyline before surgery to remove a pheochromocytoma, your healthcare provider will monitor your blood pressure and heart rate to make sure the medication is working properly. Continue taking Dibenzyline as prescribed, even if you do not notice immediate improvement. Do not increase your dose without medical advice.
Dibenzyline is primarily used to treat high blood pressure caused by pheochromocytoma, a rare tumour that releases excessive amounts of hormones that raise blood pressure. It is not commonly prescribed for people with regular high blood pressure (hypertension) because other medications are generally safer and more suitable for long-term treatment. Dibenzyline can cause side effects such as dizziness, a rapid heartbeat, and sudden drops in blood pressure, especially when standing up. If you have high blood pressure unrelated to pheochromocytoma, your healthcare provider will usually recommend other medications based on your medical history and treatment needs.
Dibenzyline is usually taken two or three times a day, depending on your prescribed dose and treatment plan. The usual starting dose for adults with pheochromocytoma is 10 mg twice daily. Your healthcare provider may gradually increase your dose based on your blood pressure, symptoms, and response to treatment. Try to take Dibenzyline at the same times each day to help maintain consistent blood pressure control. You can take the capsules with or without food. Follow your prescription label carefully, and do not take more or less medication than recommended. If you frequently experience dizziness, weakness, or low blood pressure, contact your healthcare provider. Your dose may need to be adjusted.
Dibenzyline may be prescribed to children with pheochromocytoma when a specialist determines that the medication is necessary. However, its safety and effectiveness in children have not been fully established. The appropriate dose depends on the child’s age, body weight, medical condition, and response to treatment. Children taking Dibenzyline require careful monitoring because the medication can cause low blood pressure, dizziness, and a rapid heartbeat. Your child’s healthcare provider will determine the appropriate dose and may recommend regular blood pressure and heart rate checks. Do not give Dibenzyline to a child unless it has been specifically prescribed by their healthcare provider.
No, Dibenzyline is not considered addictive or habit-forming. It does not cause drug cravings or the type of physical dependence associated with addictive medications. However, this does not mean you should stop taking it without medical advice. Dibenzyline helps control high blood pressure caused by pheochromocytoma, but it does not treat the underlying tumour. If you stop taking the medication, its blood pressure-lowering effects will gradually wear off. This may allow your blood pressure to rise again because the tumour continues to release hormones that affect your blood vessels. If you need to stop Dibenzyline, your healthcare provider will explain how to discontinue treatment safely and whether another medication is needed. Always speak with your healthcare provider before changing your dose or stopping treatment, even if your blood pressure readings have improved.
| Generic name: | Phenoxybenzamine |
|---|---|
| Formulation: | Capsule |
| Strength(s): | 10mg |
| Quantities Available: | 50, 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Dibenzyline (phenoxybenzamine) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Dibenzyline is commonly prescribed in dosages of 10 mg, taken two to three times daily. For a 90-day supply, the quantity you would order depends on your prescribed dosage.
For example, if you were prescribed 10 mg twice daily, for a 90-day supply you will order 180 capsules (90 days x 2 capsules per day).
Yes, we sell phenoxybenzamine on our website. You can enjoy low prices when you order through us. To purchase phenoxybenzamine, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You can submit your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Dibenzyline (phenoxybenzamine) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Dibenzyline (Phenoxybenzamine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Dibenzyline (Phenoxybenzamine).
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