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Actoplus Met contains two active ingredients: pioglitazone and metformin. It is a prescription medication used to help control blood sugar in adults with type 2 diabetes.
Actoplus Met is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.
It may be prescribed when one medication alone is not enough to keep blood sugar within the target range.
Actoplus Met combines two different types of diabetes medication.
Pioglitazone belongs to a group of medications called thiazolidinediones. It helps the body respond better to insulin, which allows glucose to move from the blood into the cells more effectively.
Metformin belongs to a group called biguanides. It lowers the amount of glucose made by the liver and also helps the body use insulin more effectively.
Together, these medicines help lower blood sugar levels and improve overall blood sugar control.
Actoplus Met is used for type 2 diabetes. It is not used to treat type 1 diabetes.
Continue following your recommended diet, exercise, and blood sugar monitoring plan while taking this medication.
Actoplus Met is taken by mouth with meals to help reduce stomach upset.
Your healthcare provider may tell you to take it once, twice, or sometimes three times daily, depending on your dose and current diabetes treatment.
Try to take Actoplus Met at the same time each day.
Your starting dose depends on the diabetes medications you are already taking.
If you are not currently taking pioglitazone or metformin, the usual starting dose is one tablet containing 15 mg of pioglitazone and 850 mg of metformin once daily.
Your healthcare provider may gradually increase your dose based on your blood sugar levels and how well you tolerate the medication.
The maximum recommended total daily dose is:
45 mg of pioglitazone and 2,550 mg of metformin
This equals a maximum of three 15 mg/850 mg tablets per day.
Higher metformin doses may be divided into several doses throughout the day to reduce stomach-related side effects.
If you take gemfibrozil or another strong CYP2C8 inhibitor, your maximum Actoplus Met dose is usually 15 mg/850 mg once daily.
Tell your healthcare provider about all medications and supplements you take before starting Actoplus Met.
Monitor your blood sugar as directed by your healthcare provider.
Keep a record of your readings and share them during your appointments.
Tell your healthcare provider if your blood sugar is repeatedly too high or too low, because your treatment may need to be adjusted.
Blood sugar levels may begin improving earlier, but the full effect of pioglitazone can take several weeks to a few months.
Continue taking Actoplus Met as prescribed, even if you do not notice an immediate change.
If you miss a dose, take your next dose at the regularly scheduled time.
Do not take two doses at the same time or take extra tablets to make up for a missed dose.
Actoplus Met (Pioglitazone/Metformin) is available in the following forms and strength:
Actoplus Met can cause or worsen congestive heart failure because pioglitazone may cause the body to retain fluid.
The risk may be higher if you already have heart disease.
Contact your healthcare provider right away if you develop:
Actoplus Met carries a boxed warning about this risk.
Metformin can rarely cause a serious condition called lactic acidosis.
This happens when too much lactic acid builds up in the blood and can be life-threatening.
Seek emergency medical attention if you develop symptoms such as:
The risk is higher in people with severe kidney problems and certain other medical conditions.
Tell your healthcare provider if you have liver disease or abnormal liver test results.
Your healthcare provider may check your liver function before and during treatment.
Contact your healthcare provider if you develop yellowing of the skin or eyes, dark urine, severe tiredness, or persistent nausea.
Pioglitazone has been associated with a possible increased risk of bladder cancer.
Actoplus Met may not be appropriate if you have active bladder cancer.
Tell your healthcare provider if you have a history of bladder cancer.
Contact your healthcare provider if you notice:
Actoplus Met does not usually cause low blood sugar when used by itself.
However, the risk can increase when it is taken with other diabetes medications, such as insulin or sulfonylureas.
Signs of low blood sugar may include:
Check your blood sugar as directed by your healthcare provider.
Pioglitazone can cause the body to retain fluid.
This may lead to swelling in the legs, ankles, or feet and may worsen heart failure.
Tell your healthcare provider if you develop new or worsening swelling or sudden weight gain.
Pioglitazone may increase the risk of bone fractures, particularly in women.
Talk to your healthcare provider about ways to protect your bone health if you have other risk factors for fractures.
Tell your healthcare provider if you are pregnant or planning to become pregnant.
Your diabetes treatment may need to be changed during pregnancy to maintain good blood sugar control.
Pioglitazone may also cause ovulation in some women who previously did not ovulate regularly, which may increase the chance of becoming pregnant.
Tell your healthcare provider if you are breastfeeding.
Your healthcare provider will decide whether Actoplus Met is appropriate based on your treatment needs and the possible risks to your baby.
Metformin is removed from the body through the kidneys.
Poor kidney function can increase the risk of metformin buildup and lactic acidosis.
Your healthcare provider should check your kidney function before starting Actoplus Met and periodically during treatment.
Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, and supplements you take.
Actoplus Met may interact with:
Some combinations may change your blood sugar levels or increase the risk of side effects.
Contact your healthcare provider if you develop severe swelling, rapid weight gain, shortness of breath, blood in your urine, repeated low blood sugar, or symptoms of liver or kidney problems.
Seek emergency medical care if you develop symptoms of lactic acidosis or severe breathing problems.
Take Actoplus Met exactly as prescribed by your healthcare provider. It is usually taken with meals to help reduce stomach upset. Depending on your dose, you may take it once, twice, or sometimes three times daily. Try to take it at the same time each day.
If you miss a dose, take your next dose at the regular scheduled time. Do not take two doses at once or take extra tablets to make up for the missed dose.
No. Actoplus Met does not cure type 2 diabetes. It helps lower and control blood sugar while you are taking it. Continue following your recommended diet, exercise, and blood sugar monitoring plan.
Actoplus Met does not usually cause low blood sugar when used by itself. However, the risk can increase if it is taken with other diabetes medications such as insulin or sulfonylureas, or if you skip meals. Symptoms of low blood sugar may include sweating, shaking, dizziness, hunger, fast heartbeat, or confusion. Check your blood sugar as directed and speak with your healthcare provider if low readings happen often.
| Generic name: | Pioglitazone/Metformin |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 15/500mg, 15/850mg |
| Quantities Available: | 56, 100, 112 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Actoplus Met (pioglitazone/metformin) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Actoplus Met comes in different strengths, such as pioglitazone 15 mg/metformin 850, taken once or twice daily as prescribed by your doctor. For example, if prescribed to take 15/850 mg twice daily, you would typically order 180 tablets for a 90-day supply (90 days x 2 tablets per day).
Yes, we do sell pioglitazone/metformin on our website. You can enjoy low prices on this medication. To purchase pioglitazone/metformin, you will need a valid prescription from your healthcare provider. We require this to dispense the medication. You can conveniently submit your prescription by mail, fax, or upload it through your online account.
Yes, we ship Actoplus Met (pioglitazone/metformin) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Actoplus Met (Pioglitazone/Metformin). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Actoplus Met (Pioglitazone/Metformin).
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