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Zebeta is a medication used to treat high blood pressure (hypertension) and heart failure. It contains an active ingredient called bisoprolol fumarate. It belongs to a class of medications known as beta-blockers and works by blocking the action of certain natural chemicals in the body such as adrenaline, which can cause an increase in heart rate and blood pressure.

Zebeta can be an effective medication for the treatment of high blood pressure and heart failure, but it should only be taken as directed by a healthcare professional.

Uses and Dosage

Zebeta tablet should be taken orally with or without food, as directed by your doctor, typically once a day. The dosage will be based on your medical condition and response to treatment. Take this medication regularly at the same time each day to get the most benefit from it.

The recommended dosage of Zebeta (bisoprolol fumarate) must be individualized to the needs of the patient. The usual starting dose is 5 mg once a day. In some patients, a starting dose of 2.5 mg once a day may be appropriate. Your doctor may increase your dose up to a maximum of 20 mg once a day, if necessary, but follow your doctor's instructions and do not exceed the prescribed dosage.

When using Zebeta to treat high blood pressure, it may take several weeks to achieve the full benefit of the drug. Even if you start feeling well, continue taking the medication as prescribed. Most individuals with high blood pressure exhibit no symptoms.

If your condition does not improve or worsens, such as if your blood pressure readings remain high or increase, inform your doctor.

Side Effects

Common Side Effects of Zebeta (Bisoprolol):

  • A racing heartbeat and unusual tiredness
  • Dizziness
  • Flushing or feeling unusually warm
  • Headache
  • Nausea (feeling like vomiting)
  • Peripheral edema (swelling of the ankles)

Serious Side Effects of Zebeta (Bisoprolol):

  • Breathing difficulties
  • Chest pain
  • Dark urine
  • Fever
  • Irregular heartbeat
  • Malaise
  • Rash
  • Stomach/abdominal pain
  • Swelling of the hands or feet
  • Yellowing eyes and skin

Form and Strength

Zebeta (Bisoprolol) is available in the following forms and strength:

Zebeta: Tablet

  • 5 mg
  • 10 mg

Bisoprolol: Tablet

  • 2.5 mg
  • 5 mg
  • 10 mg


  • Dizziness: Zebeta may cause dizziness, especially during the first few days of treatment or after dosage increase. Patients should avoid engaging in activities that require alertness until they know how the medication affects them.
  • Fatigue: Zebeta may cause fatigue, which can affect a patient's ability to perform certain tasks.
  • Hypotension: Zebeta may cause a drop in blood pressure, and patients should be monitored for signs of hypotension, which may include lightheadedness, fainting, or chest pain.
  • Heart failure: Zebeta may cause heart failure in some patients, especially those with pre-existing heart conditions.
  • Diabetes: Zebeta may mask certain symptoms of low blood sugar in diabetic patients.
  • Surgery: Patients should inform their healthcare provider that they are taking Zebeta before any surgical procedures, as the medication may affect the patient's response to anesthesia.
  • Respiratory disorders: Zebeta may cause breathing difficulties in patients with existing respiratory disorders.
  • Allergies: Patients with a known allergy to bisoprolol or any ingredients in Zebeta should not take the medication.
  • Kidney or liver disease: Patients with kidney or liver disease should be monitored closely while taking Zebeta, as the medication may affect their condition.
  • Thyroid disorders: Zebeta may affect the way the thyroid gland works, and patients with thyroid disorders should be monitored closely while taking the medication.
  • Pregnancy and breastfeeding: Zebeta should only be taken during pregnancy or breastfeeding if approved by a healthcare provider, as the medication may have harmful effects on the unborn baby or nursing infant.

Frequently Asked Questions (FAQ)

What is the best time to take bisoprolol?

You'll usually take bisoprolol once a day in the morning. Your doctor may advise you to take your very first dose before bedtime as it can make you feel dizzy. If you do not feel dizzy after having your first dose, take bisoprolol in the morning.

Can Zebeta be taken by pregnant or breastfeeding women?

Zebeta should only be taken during pregnancy or breastfeeding if approved by a healthcare provider, as the medication may have harmful effects on the unborn baby or nursing infant.

Is bisoprolol safe for kidneys?

Bisoprolol may be used safely in patients with renal dysfunction. No adjustment of dose is necessary for those with mild to moderate dysfunction, but in severe or end stage renal failure the dose should not exceed 10 mg once daily.

How many hours does bisoprolol last?

Effects of bisoprolol persist for 24 hours following a single dose. Blood pressure returns to baseline within two weeks of tapering a dose of bisoprolol.


Additional information

Generic name:

Bisoprolol, Bisoprolol Fumarate




2.5mg, 5mg, 10mg

Quantities Available:

30, 84, 90, 100


Additional Information Book

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Zebeta (Bisoprolol). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Zebeta (Bisoprolol).