Indications
Tarka is an oral medication indicated to treat high blood pressure and other cardiovascular conditions. It is a combination of two drugs, trandolapril and verapamil, which work together to keep blood pressure in the normal range. Tarka is indicated to lower blood pressure more effectively than if each ingredient were taken separately.
Trandolapril is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking a substance in the body that causes blood vessels to tighten. Verapamil is a calcium channel blocker (CCB). It affects the movement of calcium into the cells of the heart and blood vessels. The combination helps to relax the blood vessels, lowers blood pressure, and increases the supply of blood and oxygen to the heart.
Uses and Dosage
Tarka or the combination of trandolapril and verapamil comes as a tablet to take by mouth. It is usually taken once a day. To take Tarka, swallow the tablet whole with water once a day. Do not chew, divide, or crush the tablets. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand.
Do not take more or less of it or take it more often than prescribed. If you experience any side effects or have any concerns about taking Tarka, talk to your doctor. Do not stop taking trandolapril and verapamil without talking to your doctor.
The recommended dosage of Tarka is typically one tablet once per day with food. The tablets are available as a combination of 2 mg of trandolapril and 180 or 240 mg of verapamil. However, dosage may vary depending on the individual's medical history and blood pressure level.
Side Effect
Common Side Effects of Tarka (Trandolapril/Verapamil):
- Abnormal heart rhythm
- Constipation
- Cough
- Diarrhea
- Dizziness
- Dry cough
- Headaches
Serious Side Effects of Tarka (Trandolapril/Verapamil):
- Difficulty breathing or swallowing
- Dizziness or lightheadedness
- Excessive tiredness
- Fainting
- Fever
- Flushing (feeling of warmth)
- Heartburn
- Hoarseness
- Increase in frequency or severity of chest pain (angina)
- Rash
- Slow heartbeat
- Sore throat
- Swelling of the face, eyes, lips, tongue, arms, or legs
- Upset stomach
- Vivid, unusual dreams
- Yellowing of the skin or eyes
Form and Strength
Tarka (Trandolapril/Verapamil) is available in the following forms and strength:
Tarka: Tablet
- 2/180 mg
- 2/240 mg
Caution
- Do not take trandolapril and verapamil if you are pregnant or breastfeeding. If you become pregnant while taking trandolapril and verapamil, call your doctor immediately.
- When taking Tarka, you may experience drowsiness. Avoid driving a car or operating machinery until you are aware of how the medication affects you.
- Consuming alcohol while taking Tarka can increase the drowsiness caused by the drug. Therefore, do not drink alcohol while taking this medication.
- Trandolapril/verapamil may cause liver damage in rare cases. Let your healthcare provider know right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- The hazards of trandolapril are independent of dose, and fetal toxicity is a warning for trandolapril/verapamil.
- Tarka can cause or worsen heart failure, pulmonary edema (fluids in your lungs), and slow heartbeat. It should be avoided in people with severe heart problems or certain forms of heart failure or other heart conditions.
- Tarka can interact with grapefruit or grapefruit juice, which can increase the risk of side effects. Avoid consuming grapefruit or grapefruit juice while taking Tarka.
Frequently Asked Questions (FAQ)
Is Tarka safe to take during pregnancy?
No, pregnant women and breastfeeding mothers should not take Tarka as it can harm the fetus or infant.
Can Tarka interact with other medications?
Yes, Tarka can interact with other medications, supplements, or herbal remedies, consult with a healthcare provider before taking it.
How long does it take Tarka to work?
Tarka is a long-acting medication so it will kick in after a few hours and continue to work throughout the day. It may take about 1-2 weeks before you see the full benefits of the medication.
Can I stop taking Tarka if my blood pressure has lowered?
No, continue taking Tarka as directed by your doctor even if your blood pressure has lowered. Stopping the medication suddenly can cause your blood pressure to increase again.
What should I do if I miss a dose of Tarka?
If you miss a dose of Tarka, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Resources
- https://www.goodrx.com/trandolapril-verapamil/what-is
- https://www.mayoclinic.org/drugs-supplements/trandolapril-and-verapamil-oral-route/description/drg-20063041
- https://reference.medscape.com/drug/tarka-trandolapril-verapamil-999433
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020591s018lbl.pdf
- https://medlineplus.gov/druginfo/meds/a601128.html
- https://www.drugs.com/pregnancy/trandolapril-verapamil.html
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